Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket

Continuous flow conditions for high temperature formation of a benzodioxan pharmaceutical intermediate: Rapid scaleup for early phase material delivery

(2020) Pengbin Li et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Multiple ways to kill bacteria via inhibiting novel cell wall or membrane targets

(2020) George A Naclerio et al.   Future Medicinal Chemistry

Bacteriophage SP01 Gene Product 56 (gp56) Inhibits Bacillus subtilis Cell Division by Interacting with FtsL and Disrupting Pbp2B and FtsW Recruitment

(2020) Amit Bhambhani et al.   JOURNAL OF BACTERIOLOGY

FtsZ inhibitors as a new genera of antibacterial agents

(2019) Swayansiddha Tripathy et al.   BIOORGANIC CHEMISTRY

Benzodioxane‐Benzamides as Antibacterial Agents: Computational and SAR Studies to Evaluate the Influence of the 7‐Substitution in FtsZ Interaction

(2019) Valentina Straniero et al.   ChemMedChem

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology

(2018) Sahreena Lakhundi et al.   CLINICAL MICROBIOLOGY REVIEWS

An essential Staphylococcus aureus cell division protein directly regulates FtsZ dynamics

(2018) Prahathees J Eswara et al.   eLife

3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division

(2016) Valentina Straniero et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzodioxane–benzamides as new bacterial cell division inhibitors

(2015) Giuseppe Chiodini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Staphylococcus aureus genomics and the impact of horizontal gene transfer

(2013) Jodi A. Lindsay   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Staphylococcus aureus determinants for nasal colonization

(2012) Christopher Weidenmaier et al.   TRENDS IN MICROBIOLOGY

Multiple effects of benzamide antibiotics on FtsZ function

(2011) David W. Adams et al.   MOLECULAR MICROBIOLOGY

Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties

(2010) David J. Haydon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reclassification ofStaphylococcus aureusNasal Carriage Types

(2009) Alex van Belkum et al.   JOURNAL OF INFECTIOUS DISEASES

An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

(2008) D. J. Haydon et al.   SCIENCE