Pharmacological Inhibition and Genetic Knockdown of BCL9 Modulate the Cellular Landscape of Cancer-Associated Fibroblasts in the Tumor-Immune Microenvironment of Colorectal Cancer

Tumor Microenvironment

(2020) Borros Arneth   Medicina-Lithuania

Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapy

(2020) Yuefei Zhu et al.   Acta Pharmaceutica Sinica B

Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells

(2019) M. Feng et al.   Science Advances

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

(2018) Michael Bartoschek et al.   Nature Communications

Determinants of metastatic competency in colorectal cancer

(2017) Daniele V. F. Tauriello et al.   Molecular Oncology

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

(2017) Anna Labernadie et al.   NATURE CELL BIOLOGY

Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression

(2017) N Kramer et al.   ONCOGENE

Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen

(2016) Heather M. Brechbuhl et al.   CLINICAL CANCER RESEARCH

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer

(2015) Toshiaki Watanabe et al.   International Journal of Clinical Oncology

Stromal contribution to the colorectal cancer transcriptome

(2015) Claudio Isella et al.   NATURE GENETICS

Cancer-Associated Fibroblasts Connect Metastasis-Promoting Communication in Colorectal Cancer

(2015) Joke Tommelein et al.   Frontiers in Oncology

IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor–stroma interaction

(2014) C Rupp et al.   ONCOGENE

Role of IGF-1 Receptor in Radiation Response

(2014) Almudena Valenciano et al.   Translational Oncology

Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature

(2013) M. Herrera et al.   CLINICAL CANCER RESEARCH

Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer

(2013) S. Torres et al.   CLINICAL CANCER RESEARCH

Protumorigenic effects of Snail-expression fibroblasts on colon cancer cells

(2013) Alberto Herrera et al.   INTERNATIONAL JOURNAL OF CANCER

TIMP-1 Promotes Accumulation of Cancer Associated Fibroblasts and Cancer Progression

(2013) Yixuan Gong et al.   PLoS One

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer

(2012) C. Pena et al.   CANCER RESEARCH

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

(2012) Astrid De Boeck et al.   GUT

Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

(2012) L J A C Hawinkels et al.   ONCOGENE

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

(2012) Astrid De Boeck et al.   PROTEOMICS

Targeted Disruption of the BCL9/ -Catenin Complex Inhibits Oncogenic Wnt Signaling

(2012) K. Takada et al.   Science Translational Medicine

A Large Prospective Study of Meat Consumption and Colorectal Cancer Risk: An Investigation of Potential Mechanisms Underlying this Association

(2010) A. J. Cross et al.   CANCER RESEARCH

Podoplanin Expression Identified in Stromal Fibroblasts as a Favorable Prognostic Marker in Patients with Colorectal Carcinoma

(2009) Takahiro Yamanashi et al.   ONCOLOGY

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL