Internal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor

Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers

(2016) Svenja Lippok et al.   BIOPHYSICAL JOURNAL

Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions

(2015) Camilo Aponte-Santamaría et al.   BIOPHYSICAL JOURNAL

Shear-enhanced adsorption of a homopolymeric globule mediated by surface catch bonds

(2015) Matthias Radtke et al.   EUROPEAN PHYSICAL JOURNAL E

Shear-induced dynamics of polymeric globules at adsorbing homogeneous and inhomogeneous surfaces

(2014) Matthias Radtke et al.   EUROPEAN PHYSICAL JOURNAL E

Toward Novel Polymer-Based Materials Inspired in Blood Clotting

(2014) Alfredo Alexander-Katz   MACROMOLECULES

The various states of von Willebrand factor and their function in physiology and pathophysiology

(2014) Volker Huck et al.   THROMBOSIS AND HAEMOSTASIS

Exponential Size Distribution of von Willebrand Factor

(2013) Svenja Lippok et al.   BIOPHYSICAL JOURNAL

Von Willlebrand Adhesion to Surfaces at High Shear Rates Is Controlled by Long-Lived Bonds

(2013) Charles E. Sing et al.   BIOPHYSICAL JOURNAL

Mechanisms by which von Willebrand Disease Mutations Destabilize the A2 Domain

(2013) Amy J. Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and dynamics of blood-clotting-inspired polymer-colloid composites

(2013) Hsieh Chen et al.   Soft Matter

Blood-clotting-inspired reversible polymer–colloid composite assembly in flow

(2013) Hsieh Chen et al.   Nature Communications

A pH-regulated dimeric bouquet in the structure of von Willebrand factor

(2011) Yan-Feng Zhou et al.   EMBO JOURNAL

Conformational dynamics and internal friction in homopolymer globules: equilibrium vs. non-equilibrium simulations

(2011) T. R. Einert et al.   EUROPEAN PHYSICAL JOURNAL E

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

(2011) R. SCHNEPPENHEIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biology and physics of von Willebrand factor concatamers

(2011) T. A. SPRINGER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Calcium modulates force sensing by the von Willebrand factor A2 domain

(2011) Arjen J. Jakobi et al.   Nature Communications

Unfolding the A2 Domain of Von Willebrand Factor with the Optical Trap

(2010) Junyi Ying et al.   BIOPHYSICAL JOURNAL

Elongational Flow Induces the Unfolding of von Willebrand Factor at Physiological Flow Rates

(2010) Charles E. Sing et al.   BIOPHYSICAL JOURNAL

Pathophysiology of thrombotic thrombocytopenic purpura

(2010) Han-Mou Tsai   INTERNATIONAL JOURNAL OF HEMATOLOGY

Factor VIII and Platelets Synergistically Accelerate Cleavage of von Willebrand Factor by ADAMTS13 under Fluid Shear Stress

(2010) Christopher G. Skipwith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis

(2009) C. BALDAUF et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura

(2008) J. E. Sadler   BLOOD

Dynamics and Instabilities of Collapsed Polymers in Shear Flow

(2008) A. Alexander-Katz et al.   MACROMOLECULES

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

(2008) W. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA