Whole-brain activation signatures of weight-lowering drugs

The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas

(2020) Quanxin Wang et al.   CELL

Claustral Neurons Projecting to Frontal Cortex Mediate Contextual Association of Reward

(2020) Anna Terem et al.   CURRENT BIOLOGY

A basal ganglia-like cortical–amygdalar–hypothalamic network mediates feeding behavior

(2020) Marie Barbier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Optimized Mouse Brain Atlas for Automated Mapping and Quantification of Neuronal Activity Using iDISCO+ and Light Sheet Fluorescence Microscopy

(2020) Johanna Perens et al.   NEUROINFORMATICS

The melanocortin pathway and control of appetite-progress and therapeutic implications

(2019) Giulia Baldini et al.   JOURNAL OF ENDOCRINOLOGY

Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation

(2019) Sharma et al.   MOLECULES

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

An up-to-date evaluation of lorcaserin hydrochloride for the treatment of obesity

(2019) Beverly G. Tchang et al.   EXPERT OPINION ON PHARMACOTHERAPY

Monoamines as Drug Targets in Chronic Pain: Focusing on Neuropathic Pain

(2019) Lidia Bravo et al.   Frontiers in Neuroscience

Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons

(2018) Jessica M. Adams et al.   DIABETES

Centrally Acting Agents for Obesity: Past, Present, and Future

(2018) Ann A. Coulter et al.   DRUGS

Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake

(2018) Giuseppe D'Agostino et al.   Cell Metabolism

Activation of the rat hypothalamic supramammillary nucleus by food anticipation, food restriction or ghrelin administration

(2018) Marie V. Le May et al.   JOURNAL OF NEUROENDOCRINOLOGY

Probabilistic TFCE: A generalized combination of cluster size and voxel intensity to increase statistical power

(2018) Tamás Spisák et al.   NEUROIMAGE

Blaming the Brain for Obesity: Integration of Hedonic and Homeostatic Mechanisms

(2017) Hans-Rudolf Berthoud et al.   GASTROENTEROLOGY

Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists

(2017) Guy A Higgins et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Paraventricular Thalamic Control of Food Intake and Reward: Role of Glucagon-Like Peptide-1 Receptor Signaling

(2017) Zhi Yi Ong et al.   NEUROPSYCHOPHARMACOLOGY

Cannabinoid Receptor Signaling in Central Regulation of Feeding Behavior: A Mini-Review

(2017) Marco Koch   Frontiers in Neuroscience

Lorcaserin improves glycemic control via a melanocortin neurocircuit

(2017) Luke K. Burke et al.   Molecular Metabolism

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

(2017) Tinh-Hai Collet et al.   Molecular Metabolism

Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

(2017) Joseph Tam et al.   Molecular Metabolism

Neuronal systems and circuits involved in the control of food intake and adaptive thermogenesis

(2016) Alexandre Caron et al.   Annals of the New York Academy of Sciences

Mapping of Brain Activity by Automated Volume Analysis of Immediate Early Genes

(2016) Nicolas Renier et al.   CELL

Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events

(2016) Rohan Khera et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Elucidation of the anatomy of a satiety network: Focus on connectivity of the parabrachial nucleus in the adult rat

(2016) Györgyi Zséli et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Homeostasis Meets Motivation in the Battle to Control Food Intake

(2016) Carrie R. Ferrario et al.   JOURNAL OF NEUROSCIENCE

Central nervous system regulation of eating: Insights from human brain imaging

(2016) Olivia M. Farr et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Lateral hypothalamic circuits for feeding and reward

(2016) Garret D Stuber et al.   NATURE NEUROSCIENCE

Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward

(2016) Rahul Pandit et al.   NEUROPSYCHOPHARMACOLOGY

Genetically and functionally defined NTS to PBN brain circuits mediating anorexia

(2016) Carolyn W. Roman et al.   Nature Communications

A review of dopamine agonist therapy in type 2 diabetes and effects on cardio-metabolic parameters

(2016) E.M. Lamos et al.   Primary Care Diabetes

Neural Control of Energy Balance: Translating Circuits to Therapies

(2015) Laurent Gautron et al.   CELL

Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice

(2015) C. Clemmensen et al.   EMBO Molecular Medicine

Neural Responses to Macronutrients: Hedonic and Homeostatic Mechanisms

(2015) Alastair J. Tulloch et al.   GASTROENTEROLOGY

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

(2015) Jesper Lau et al.   JOURNAL OF MEDICINAL CHEMISTRY

Limbic circuitry of the midline thalamus

(2015) Robert P. Vertes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

(2014) Anna Secher et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal GLP1R mediates liraglutide’s anorectic but not glucose-lowering effect

(2014) Stephanie Sisley et al.   JOURNAL OF CLINICAL INVESTIGATION

Melanocortin 4 Receptors Reciprocally Regulate Sympathetic and Parasympathetic Preganglionic Neurons

(2013) Jong-Woo Sohn et al.   CELL

5-HT2C Receptor Agonist Anorectic Efficacy Potentiated by 5-HT1B Receptor Agonist Coapplication: An Effect Mediated via Increased Proportion of Pro-Opiomelanocortin Neurons Activated

(2013) B. Doslikova et al.   JOURNAL OF NEUROSCIENCE

Thalamic Contribution to Cortical Processing of Taste and Expectation

(2013) C. L. Samuelsen et al.   JOURNAL OF NEUROSCIENCE

Genetic identification of a neural circuit that suppresses appetite

(2013) Matthew E. Carter et al.   NATURE

Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques

(2012) P. Kievit et al.   DIABETES

Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons

(2012) Marcelo O. Dietrich et al.   NATURE REVIEWS DRUG DISCOVERY

Food reward, hyperphagia, and obesity

(2011) Hans-Rudolf Berthoud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Central Endocannabinoid Signaling Regulates Hepatic Glucose Production and Systemic Lipolysis

(2011) J. D. O'Hare et al.   DIABETES

The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide

(2011) Scott E. Kanoski et al.   NEUROPHARMACOLOGY

Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice

(2010) Neil E. Rowland et al.   PEPTIDES

Hypothalamic nutrient sensing in the control of energy homeostasis

(2009) Clémence Blouet et al.   BEHAVIOURAL BRAIN RESEARCH

Duloxetine in the treatment of generalized anxiety disorder

(2009) Susan G Kornstein et al.   Expert Review of Neurotherapeutics

elastix: A Toolbox for Intensity-Based Medical Image Registration

(2009) S. Klein et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Gastrointestinal hormone actions in the central regulation of energy metabolism: potential sensory roles for the circumventricular organs

(2009) T D Hoyda et al.   INTERNATIONAL JOURNAL OF OBESITY

Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice

(2009) K. Ganesh Kumar et al.   PEPTIDES

Role of central melanocortin pathways in energy homeostasis

(2009) Alastair S. Garfield et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Bromocriptine Administration Reduces Hyperphagia and Adiposity and Differentially Affects Dopamine D2 Receptor and Transporter Binding in Leptin-Receptor-Deficient Zucker Rats and Rats with Diet-Induced Obesity

(2008) Lisa M. Davis et al.   NEUROENDOCRINOLOGY

Effects of a Novel Y5 Antagonist in Obese Mice: Combination With Food Restriction or Sibutramine

(2008) Satoshi Mashiko et al.   Obesity

Feeding Induced by Cannabinoids Is Mediated Independently of the Melanocortin System

(2008) Puspha Sinnayah et al.   PLoS One

The vagus nerve, food intake and obesity

(2008) Hans-Rudolf Berthoud   REGULATORY PEPTIDES