Restoration of NK Cell Cytotoxic Function With Elotuzumab and Daratumumab Promotes Elimination of Circulating Plasma Cells in Patients With SLE

The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections

(2020) Eri Katsuyama et al.   Cell Reports

Glucocorticoids and the cytokines IL-12, IL-15 and IL-18 present in the tumor microenvironment induce PD-1 expression on human Natural Killer cells

(2020) Linda Quatrini et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Changes of frequency and expression level of CD161 in CD8 + T cells and natural killer T cells in peripheral blood of patients with systemic lupus erythematosus

(2020) Yumi Park et al.   MICROBIOLOGY AND IMMUNOLOGY

Autoimmunity and organ damage in systemic lupus erythematosus

(2020) George C. Tsokos   NATURE IMMUNOLOGY

Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus

(2020) Lennard Ostendorf et al.   NEW ENGLAND JOURNAL OF MEDICINE

CyTOFmerge: Integrating mass cytometry data across multiple panels

(2019) Tamim Abdelaal et al.   BIOINFORMATICS

New therapies for systemic lupus erythematosus — past imperfect, future tense

(2019) Grainne Murphy et al.   Nature Reviews Rheumatology

Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness

(2019) Filip Segerberg et al.   Frontiers in Immunology

Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype

(2018) Abel Suárez-Fueyo et al.   JOURNAL OF IMMUNOLOGY

Elotuzumab: A Review in Relapsed and/or Refractory Multiple Myeloma

(2018) Yvette N. Lamb   DRUGS

SLAMF1 engagement inhibits T cell-B cell interaction and diminishes IL-6 production and plasmablast differentiation in systemic lupus erythematosus

(2018) Maria P. Karampetsou et al.   Arthritis & Rheumatology

Signaling lymphocyte activation molecule family in systemic lupus erythematosus

(2018) Denis Comte et al.   CLINICAL IMMUNOLOGY

2B4 (CD244, SLAMF4) and CS1 (CD319, SLAMF7) in systemic lupus erythematosus and cancer

(2018) Joseph D. Malaer et al.   CLINICAL IMMUNOLOGY

SLAM family receptors in natural killer cells – Mediators of adhesion, activation and inhibition via cis and trans interactions

(2018) Maren Claus et al.   CLINICAL IMMUNOLOGY

Signaling Lymphocytic Activation Molecule Family Member 7 Engagement Restores Defective Effector CD8+ T Cell Function in Systemic Lupus Erythematosus

(2017) Denis Comte et al.   Arthritis & Rheumatology

Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus

(2017) Maria P. Karampetsou et al.   PLoS One

The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education

(2016) Shasha Chen et al.   IMMUNITY

Engagement of SLAMF3 enhances CD4+T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus

(2016) Denis Comte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity

(2015) Vaishali R. Moulton et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent findings on the role of natural killer cells in the pathogenesis of systemic lupus erythematosus

(2015) R. Spada et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Analysis of expression and function of the co-stimulatory receptor SLAMF1 in immune cells from patients with systemic lupus erythematosus (SLE)

(2015) L Liñán-Rico et al.   LUPUS

Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma

(2015) Sagar Lonial et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus

(2015) Katalin Kis-Toth et al.   Arthritis & Rheumatology

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) – cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland

(2015) C Ribi et al.   SWISS MEDICAL WEEKLY

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

The role of Tumor Necrosis Factor-alpha (TNF-α) in the pathogenesis of systemic lupus erythematosus

(2011) Mariana Postal et al.   CYTOKINE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE