Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo

Humanization of Immunodeficient Animals for the Modeling of Transplantation, Graft Versus Host Disease and Regenerative Medicine

(2020) George Adigbli et al.   TRANSPLANTATION

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

(2020) Peng Hua et al.   BLOOD

Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source

(2020) Nicholas J. Hess et al.   Frontiers in Immunology

Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking

(2019) Jingzhu Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Transiently Activated Human Regulatory T Cells Upregulate BCL-XL Expression and Acquire a Functional Advantage in vivo

(2019) Fadi Issa et al.   Frontiers in Immunology

Challenges and Opportunities for Consistent Classification of Human B Cell and Plasma Cell Populations

(2019) Ignacio Sanz et al.   Frontiers in Immunology

A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells

(2018) Keisuke Sumide et al.   Nature Communications

Factors Influencing the Umbilical Cord Blood Stem Cell Industry: An Evolving Treatment Landscape

(2018) Carla Dessels et al.   Stem Cells Translational Medicine

The number of CD34+CD133+ hematopoietic stem cells residing in umbilical cord blood (UCB) units is not correlated with the numbers of total nucleated cells and CD34+ cells: a possible new indicator for quality evaluation of UCB units

(2018) Yoshikazu Matsuoka et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Improved multilineage human hematopoietic reconstitution and function in NSGS mice

(2018) Mark Wunderlich et al.   PLoS One

Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice

(2017) Paul H. Miller et al.   EXPERIMENTAL HEMATOLOGY

Complement Depletion Improves Human Red Blood Cell Reconstitution in Immunodeficient Mice

(2017) Bing Chen et al.   Stem Cell Reports

Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4

(2016) Chao-Hui Chang et al.   STEM CELLS

A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion

(2016) Marina Tarunina et al.   STEM CELLS AND DEVELOPMENT

Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice

(2016) Susann Rahmig et al.   Stem Cell Reports

Humanized hemato-lymphoid system mice

(2015) A. P. A. Theocharides et al.   HAEMATOLOGICA

Receptor editing and genetic variability in human autoreactive B cells

(2015) Julie Lang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Humanized hemato-lymphoid system mice

(2015) A. P. A. Theocharides et al.   HAEMATOLOGICA

Nonirradiated NOD,B6.SCID Il2rγ−/− KitW41/W41 (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells

(2015) Brian E. McIntosh et al.   Stem Cell Reports

Kit Regulates HSC Engraftment across the Human-Mouse Species Barrier

(2014) Kadriye Nehir Cosgun et al.   Cell Stem Cell

Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

(2013) Anthony Rongvaux et al.   Annual Review of Immunology

CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells

(2013) M Takahashi et al.   LEUKEMIA

Homing of Regulatory T Cells to Human Skin Is Important for the Prevention of Alloimmune-Mediated Pathology in an In Vivo Cellular Therapy Model

(2013) Fadi Issa et al.   PLoS One

An intrinsic BM hematopoietic niche occupancy defect of HSC in scid mice facilitates exogenous HSC engraftment

(2011) Y. Qing et al.   BLOOD

Macrophages prevent human red blood cell reconstitution in immunodeficient mice

(2011) Z. Hu et al.   BLOOD

Human immune system mice: current potential and limitations for translational research on human antibody responses

(2011) Raja Vuyyuru et al.   IMMUNOLOGIC RESEARCH

Humanized mouse models to study human diseases

(2011) Michael A Brehm et al.   Current Opinion in Endocrinology Diabetes and Obesity

The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood

(2011) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

Comparison of human cord blood engraftment between immunocompromised mouse strains

(2010) S. P. McDermott et al.   BLOOD

Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation

(2010) Michael A. Brehm et al.   CLINICAL IMMUNOLOGY

In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

(2010) Satish N Nadig et al.   NATURE MEDICINE

The Density of CD10 Corresponds to Commitment and Progression in the Human B Lymphoid Lineage

(2010) Michiko Ichii et al.   PLoS One

Ex Vivo–Expanded Human Regulatory T Cells Prevent the Rejection of Skin Allografts in a Humanized Mouse Model

(2010) Fadi Issa et al.   TRANSPLANTATION

The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice)

(2009) Yohei Watanabe et al.   INTERNATIONAL IMMUNOLOGY

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

Human BLyS Facilitates Engraftment of Human PBL Derived B Cells in Immunodeficient Mice

(2008) Madelyn R. Schmidt et al.   PLoS One