Systematic Approach to DNA Aptamer Design Using Amino Acid–Nucleic Acid Hybrids (ANHs) Targeting Thrombin

EXPANDING THE RECOGNITION INTERFACE OF THE THROMBIN BINDING APTAMER HD1 THROUGH MODIFICATION OF RESIDUES T3 AND T12

(2021) Igor Smirnov et al.   Molecular Therapy-Nucleic Acids

Improving Thermodynamic Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Incorporation of 8-trifluoromethyl-2′-deoxyguanosine

(2020) Hong-Liang Bao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic applications of AS1411 aptamer, an update review

(2019) Rezvan Yazdian-Robati et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

G-Quadruplex-Forming Aptamers—Characteristics, Applications, and Perspectives

(2019) Carolina Roxo et al.   MOLECULES

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

(2018) Rafal Dolot et al.   NUCLEIC ACIDS RESEARCH

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

(2018) Weronika Kotkowiak et al.   Molecular Therapy-Nucleic Acids

A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats

(2018) Boshi Fu et al.   CHEMICAL COMMUNICATIONS

Identification of a new serine protease from polychaeta, Marphysa sanguinea, for its thrombolytic and anticoagulant activity

(2017) Seung Ju Yeon et al.   KOREAN JOURNAL OF CHEMICAL ENGINEERING

Mapping the affinity landscape of Thrombin-binding aptamers on 2′F-ANA/DNA chimeric G-Quadruplex microarrays

(2017) Jory Lietard et al.   NUCLEIC ACIDS RESEARCH

Electrochemical Aptasensor of Cardiac Troponin I for the Early Diagnosis of Acute Myocardial Infarction

(2015) Hunho Jo et al.   ANALYTICAL CHEMISTRY

Highly Stable Duplex Formation by Artificial Nucleic Acids Acyclic Threoninol Nucleic Acid (aTNA) and Serinol Nucleic Acid (SNA) with Acyclic Scaffolds

(2013) Keiji Murayama et al.   CHEMISTRY-A EUROPEAN JOURNAL

A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma

(2013) Jonathan E. Rosenberg et al.   INVESTIGATIONAL NEW DRUGS

Aptamer carbon nanodot sandwich used for fluorescent detection of protein

(2012) Bailu Xu et al.   ANALYST

Ultrasensitive and Selective Electrochemical Diagnosis of Breast Cancer Based on a Hydrazine–Au Nanoparticle–Aptamer Bioconjugate

(2012) Ye Zhu et al.   ANALYTICAL CHEMISTRY

Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications

(2012) Anna Avino et al.   CURRENT PHARMACEUTICAL DESIGN

G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application

(2012) W. O. Tucker et al.   CURRENT PHARMACEUTICAL DESIGN

Loop residues of thrombin-binding DNA aptamer impact G-quadruplex stability and thrombin binding

(2011) Satoru Nagatoishi et al.   BIOCHIMIE

Improving the Stability of Aptamers by Chemical Modification

(2011) R. E. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Aptamer conjugated magnetic nanoparticles as nanosurgeons

(2010) Baiju G Nair et al.   NANOTECHNOLOGY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

The Chemical Biology of Aptamers

(2009) Günter Mayer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS

In vivo selection of tumor-targeting RNA motifs

(2009) Jing Mi et al.   Nature Chemical Biology

4-Thio-deoxyuridylate-modified thrombin aptamer and its inhibitory effect on fibrin clot formation, platelet aggregation and thrombus growth on subendothelial matrix

(2008) S. MENDELBOUM RAVIV et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS