Naofucong Ameliorates High Glucose Induced Hippocampal Neuron Injury Through Suppressing P2X7/NLRP1/Caspase-1 Pathway

Best practice in research – Overcoming common challenges in phytopharmacological research

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NLRP1 and NTN1, Deregulated Blood Differentially Methylated Regions in Mild Cognitive Impairment Patients

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Sarsasapogenin suppresses Aβ overproduction induced by high glucose in HT-22 cells

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Effect of Chinese herbal compound Naofucong (脑复聪) on the inflammatory process induced by high glucose in BV-2 cells

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Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels

(2016) Go Kasuya et al.   Cell Reports

NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

(2015) Chen-Chen Tan et al.   Journal of Neuroinflammation

Magnitude of Cognitive Dysfunction in Adults with Type 2 Diabetes: A Meta-analysis of Six Cognitive Domains and the Most Frequently Reported Neuropsychological Tests Within Domains

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P2X7 receptor: an emerging target in central nervous system diseases

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Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

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Prevalence and Control of Diabetes in Chinese Adults

(2013) Yu Xu   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

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Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

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Metabolic Syndrome, Insulin Resistance, and Roles of Inflammation – Mechanisms and Therapeutic Targets

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NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells

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HT22 hippocampal neuronal cell line possesses functional cholinergic properties

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