MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling

Involvement of CXCL12/CXCR4 in the motility of human first-trimester endometrial epithelial cells through an autocrine mechanism by activating PI3K/AKT signaling

(2020) Jiayi Zheng et al.   BMC Pregnancy and Childbirth

Milk Fat Globule‐EGF Factor 8 improves Hepatic Steatosis and Inflammation

(2020) Lei Zhang et al.   HEPATOLOGY

HMGB1-Mediated Neuroinflammatory Responses in Brain Injuries: Potential Mechanisms and Therapeutic Opportunities

(2020) Yam Nath Paudel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aneurysmal Subarachnoid Hemorrhage: the Last Decade

(2020) Sean N. Neifert et al.   Translational Stroke Research

The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage

(2019) Toshio Fumoto et al.   Translational Stroke Research

Healthcare Economics of Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage in the United States

(2019) Syed M. Adil et al.   Translational Stroke Research

The blood–brain barrier as an endocrine tissue

(2019) William A. Banks   Nature Reviews Endocrinology

Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage

(2019) Svetlana Lublinsky et al.   EBioMedicine

Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats

(2019) Jikai Wang et al.   Journal of Stroke & Cerebrovascular Diseases

Polymorphisms of MFGE8 are associated with susceptibility and clinical manifestations through gene expression modulation in Koreans with systemic lupus erythematosus

(2019) Wook-Young Baek et al.   Scientific Reports

Naringin enhances endothelial progenitor cell (EPC) proliferation and tube formation capacity through the CXCL12/CXCR4/PI3K/Akt signaling pathway

(2018) Zhihu Zhao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Endothelial Cell Dysfunction and Injury in Subarachnoid Hemorrhage

(2018) T. Peeyush Kumar et al.   MOLECULAR NEUROBIOLOGY

Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury

(2018) Yong-Yue Gao et al.   Cell Death & Disease

Neurogenesis changes and the fate of progenitor cells after subarachnoid hemorrhage in rats

(2018) Yuchun Zuo et al.   EXPERIMENTAL NEUROLOGY

CXCL12/CXCR4 promotes proliferation, migration, and invasion of adamantinomatous craniopharyngiomas via PI3K/AKT signal pathway

(2018) Xiaohong Yin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Time Trends in Outcomes After Aneurysmal Subarachnoid Hemorrhage Over the Past 30 Years

(2018) Biagia La Pira et al.   MAYO CLINIC PROCEEDINGS

Neuroanatomy- and Pathology-Based Functional Examinations of Experimental Stroke in Rats: Development and Validation of a New Behavioral Scoring System

(2018) Shin-Joe Yeh et al.   Frontiers in Behavioral Neuroscience

The Contractile Apparatus Is Essential for the Integrity of the Blood-Brain Barrier After Experimental Subarachnoid Hemorrhage

(2018) Clara Luh et al.   Translational Stroke Research

Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice

(2018) Yuchun Zuo et al.   Frontiers in Molecular Neuroscience

CXCL12 has therapeutic value in facial nerve injury and promotes Schwann cells autophagy and migration via PI3K-AKT-mTOR signal pathway

(2018) Dekun Gao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Danshensu accelerates angiogenesis after myocardial infarction in rats and promotes the functions of endothelial progenitor cells through SDF-1α/CXCR4 axis

(2017) Ying Yin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt PathwayNovelty and Significance

(2017) Ke-Qiong Deng et al.   HYPERTENSION

Vitamin D attenuates cerebral artery remodeling through VDR/AMPK/eNOS dimer phosphorylation pathway after subarachnoid hemorrhage in rats

(2017) Budbazar Enkhjargal et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mesenchymal stem cells-derived MFG-E8 accelerates diabetic cutaneous wound healing

(2017) Akihiko Uchiyama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

MFG-E8-derived peptide attenuates adhesion and migration of immune cells to endothelial cells

(2017) Yohei Hirano et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Spontaneous subarachnoid haemorrhage

(2017) R Loch Macdonald et al.   LANCET

Cigarette smoke attenuates phagocytic ability of macrophages through down-regulating Milk fat globule-EGF factor 8 (MFG-E8) expressions

(2017) Yueqin Wang et al.   Scientific Reports

Progesterone modulates endothelial progenitor cell (EPC) viability through the CXCL12/CXCR4/PI3K/Akt signalling pathway

(2016) Peng Yu et al.   CELL PROLIFERATION

Myeloid-Epithelial-Reproductive Receptor Tyrosine Kinase and Milk Fat Globule Epidermal Growth Factor 8 Coordinately Improve Remodeling After Myocardial Infarction via Local Delivery of Vascular Endothelial Growth FactorCLINICAL PERSPECTIVE

(2016) Kiave-Yune Howangyin et al.   CIRCULATION

Mesenchymal stem cells and endothelial progenitor cells accelerate intra-aneurysmal tissue organization after treatment with SDF-1α-coated coils

(2016) Yuyuan Gao et al.   NEUROLOGICAL RESEARCH

MFGE8/Integrin β3 pathway alleviates apoptosis and inflammation in early brain injury after subarachnoid hemorrhage in rats

(2015) Fei Liu et al.   EXPERIMENTAL NEUROLOGY

Prenatal genesis of layer II doublecortin expressing neurons in neonatal and young adult guinea pig cerebral cortex

(2015) Yan Yang et al.   Frontiers in Neuroanatomy

Integrin αvβ5 in endothelial cells of rat splenic sinus: an immunohistochemical and ultrastructural study

(2014) Kiyoko Uehara et al.   CELL AND TISSUE RESEARCH

SDF-1/CXCR4 Axis in Tie2-Lineage Cells Including Endothelial Progenitor Cells Contributes to Bone Fracture Healing

(2014) Yohei Kawakami et al.   JOURNAL OF BONE AND MINERAL RESEARCH

CXCL12/Stromal-Cell-Derived Factor-1 Effectively Replaces Endothelial Progenitor Cells to Induce Vascularized Ectopic Bone

(2014) Rhandy M. Eman et al.   STEM CELLS AND DEVELOPMENT

Recombinant Milk Fat Globule–EGF Factor-8 Reduces Oxidative Stress via Integrin β3/Nuclear Factor Erythroid 2–Related Factor 2/Heme Oxygenase Pathway in Subarachnoid Hemorrhage Rats

(2014) Fei Liu et al.   STROKE

MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation

(2012) M. Fricker et al.   JOURNAL OF NEUROSCIENCE

MFG-E8 Released by Apoptotic Endothelial Cells Triggers Anti-Inflammatory Macrophage Reprogramming

(2012) Marie-Joëlle Brissette et al.   PLoS One

Review: milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation

(2011) Monowar Aziz et al.   APOPTOSIS

Abrogation of Cbl–PI3K Interaction Increases Bone Formation and Osteoblast Proliferation

(2011) Tracy Brennan et al.   CALCIFIED TISSUE INTERNATIONAL

Microthrombosis after experimental subarachnoid hemorrhage: Time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan

(2011) Jared M. Pisapia et al.   EXPERIMENTAL NEUROLOGY

Uncoupling of Endothelial Nitric Oxide Synthase after Experimental Subarachnoid Hemorrhage

(2010) Mohammed Sabri et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

SED1/MFG-E8: A Bi-Motif protein that orchestrates diverse cellular interactions

(2009) Adam Raymond et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS