Article
Biology
Fu Zeng, Adam Zaidel, Aihua Chen, Christopher R. Fetsch
Summary: The adult brain shows remarkable plasticity by recalibrating its perceptual estimates based on information from multiple sensory sources. In this study, single-neuron activity was recorded in monkeys' brains, revealing that early multisensory cortices participate in unsupervised recalibration, while the VIP area reflects a global shift in vestibular space.
Article
Neurosciences
Adam Zaidel, Jean Laurens, Gregory C. DeAngelis, Dora E. Angelaki
Summary: This study found that adult rhesus macaques show little neural plasticity in the lower-level multisensory cortical area MSTd, but exhibit neural plasticity in the higher-level multisensory area VIP. The systematic shifts in VIP tuning curves were observed, reflecting the decision-related component of the population response. The results demonstrate neuronal calibration in single sessions, laying the foundation for understanding multisensory neural plasticity in maintaining accuracy for sensorimotor tasks.
JOURNAL OF NEUROSCIENCE
(2021)
Review
Clinical Neurology
Bingyu Liu, Jiayu Shan, Yong Gu
Summary: The vestibular system plays a crucial role in various cognitive functions, and recent studies have shed light on its neural mechanisms. However, the complex spatiotemporal dynamics of vestibular signals pose challenges in integrating them with other modalities.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
David L. Barack, Michael L. Platt
Summary: Animals engage in routine behavior to navigate their environments efficiently, which may be influenced by environmental factors such as reward location. The study found that neurons in the posterior cingulate cortex tracked environmental information but not rewards, and as the environment became more familiar, animals tended to deviate from routine behaviors.
JOURNAL OF NEUROSCIENCE
(2021)
Review
Clinical Neurology
Megan J. Kobel, Andrew R. Wagner, Daniel M. Merfeld, Jameson K. Mattingly
Summary: Vestibular perceptual thresholds have shown promise in detecting characteristic changes in vestibular pathologies and sub-clinical declines in vestibular function. Further research is needed to explore the potential applications and limitations in the diagnosis of vestibular disorders.
FRONTIERS IN NEUROLOGY
(2021)
Review
Biology
Steven J. Jerjian, Devin R. Harsch, Christopher R. Fetsch
Summary: In order to navigate and guide adaptive behaviour in a dynamic environment, animals need to accurately estimate their own motion relative to the external world. This process involves the integration of visual, vestibular and kinesthetic inputs. Recent research has shown that time and certainty are crucial for self-motion perception and decision-making in navigation. By extending current models, researchers have been able to study confidence in heading discrimination and explore the connection between self-motion perception and navigation. Overall, this study offers promise for a deeper understanding of spatial perception and decision-making in behaving animals.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Article
Clinical Neurology
Elena Calzolari, Mariya Chepisheva, Rebecca M. Smith, Mohammad Mahmud, Peter J. Hellyer, Vassilios Tahtis, Qadeer Arshad, Amy Jolly, Mark Wilson, Heiko Rust, David J. Sharp, Barry M. Seemungal
Summary: Vestibular dysfunction is common in patients with TBI and requires a multi-level assessment due to the varied areas of damage. Patients with vestibular agnosia experience more severe imbalance, potentially linked to direct and indirect effects of white matter tract damage in the brain.
Article
Neurosciences
Milou J. L. Van Helvert, Luc P. J. Selen, Robert J. Van Beers, W. Pieter Medendorp
Summary: This study found that training humans to control a self-motion platform leads to the construction of an accurate internal model that maps steering movements to vestibular signals. It demonstrates that vestibular feedback allows for both online control and rapid adaptation to gain changes.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Review
Behavioral Sciences
Atsushi Noritake, Taihei Ninomiya, Masaki Isoda
Summary: Primates are group-living creatures that face challenges of complex social demands. While cortical mechanisms have been a major focus, there is evidence that subcortical regions also play a role in processing information from other agents. Signals related to self and others are integrated into a social utility signal, facilitating optimal decision-making in accordance with social demands.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Multidisciplinary Sciences
Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond, Lisa M. Giocomo
Summary: Neural circuits in the medial temporal lobe construct a map-like representation of space that supports navigation by integrating multiple sensory cues and cues related to the individual's movement through the environment. The medial entorhinal cortex (MEC) encodes three-dimensional head movement, eye position, and velocity, alongside other self-motion signals in individual neurons, such as body position, running speed, and azimuthal head direction.
NATURE COMMUNICATIONS
(2021)
Article
Clinical Neurology
Lisa van Stiphout, Florence Lucieer, Maksim Pleshkov, Vincent Van Rompaey, Josine Widdershoven, Nils Guinand, Angelica Perez Fornos, Herman Kingma, Raymond van de Berg
Summary: The study found that perceptual self-motion thresholds are significantly higher in patients with bilateral vestibulopathy compared to control subjects, and are generally associated with lower vestibular test results.
JOURNAL OF NEUROLOGY
(2022)
Article
Behavioral Sciences
Claudio Galletti, Michela Gamberini, Patrizia Fattori
Summary: In the macaque, the posterior parietal area V6A is involved in the control of reach-to-grasp actions, including the transport and grasping phases. It acts as a state estimator to maintain consistency between ongoing and desired movements, and can encode the target of an action. Additionally, it may use attention to guide goal-directed hand movements and has a specific priority map for reaching arm movement.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Neurosciences
Omid A. Zobeiri, Benjamin Ostrander, Jessica Roat, Yuri Agrawal, Kathleen E. Cullen
Summary: Research indicates that damage to the vestibular system significantly alters the statistical characteristics of head movements, particularly evident in tasks that require rapid feedback.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Computer Science, Information Systems
Dan Wu, Youwei Zeng, Ruiyang Gao, Shenjie Li, Yang Li, Rahul C. Shah, Hong Lu, Daqing Zhang
Summary: WiTraj is a device-free indoor motion tracking system that utilizes commodity WiFi devices. It improves tracking robustness by enhancing signal parameter estimation, leveraging multiple receivers, and differentiating walking from in-place activities.
IEEE TRANSACTIONS ON MOBILE COMPUTING
(2023)
Review
Neurosciences
Luxin Zhou, Yong Gu
Summary: Accurate self-motion perception is crucial for survival, and it involves multiple sensory cues such as optic flow and inertial motion. Recent studies challenge previous conventional thoughts about the cortical mechanisms underlying visuo-vestibular integration and propose that different temporal component signals may mediate different functions in multisensory self-motion perception.
NEUROSCIENCE BULLETIN
(2023)
Article
Biology
Lihua Yang, Yong Gu
Article
Neurosciences
Junxiang Luo, Keyan He, Ian Max Andolina, Xiaohong Li, Jiapeng Yin, Zheyuan Chen, Yong Gu, Wei Wang
JOURNAL OF NEUROSCIENCE
(2019)
Article
Biology
Wen-Hao Zhang, He Wang, Aihua Chen, Yong Gu, Tai Sing Lee, K. Y. Michael Wong, Si Wu
Article
Cell Biology
Qihao Zheng, Luxin Zhou, Yong Gu
Summary: The study investigates the integration of optic flow and vestibular cues in precise heading perception, finding that adjusting visual stimuli to lead vestibular cues can improve heading performance. This alignment is associated with nonlinear gain modulation effects, facilitating cue integration in certain brain areas.
Article
Multidisciplinary Sciences
Wenhao Li, Jianyu Lu, Zikang Zhu, Yong Gu
Summary: The extrastriate visual cortex plays a role in encoding optic flow, but its direct link to perception has not been established. In this study, the authors used electrical microstimulation to reveal that roll signals in MSTd contribute to rotation perception. These findings provide important evidence for understanding the neural mechanisms underlying perception of rotation.
NATURE COMMUNICATIONS
(2022)
Review
Biology
Zhao Zeng, Ce Zhang, Yong Gu
Summary: Multi-sensory decision making (MSDM) is crucial for making accurate decisions in complex environments. Recent research in computational theory, psychophysical behavior, and neurophysiology has made significant progress in understanding MSDM. By studying a visuo-vestibular heading model system, researchers have uncovered the complex temporal dynamics of vestibular signals in various brain regions, challenging the brain's ability to integrate cues across time and sensory modalities. Moreover, new evidence from higher-level decision-related areas has revised our understanding of how signals from different sensory modalities are processed and accumulated to form a unified perceptual decision.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)