Insight into the human pathodegradome of the V8 protease from Staphylococcus aureus

Identification of unexplored substrates of the serine protease, thrombin, using N-terminomics strategy

(2019) Sonali R. Bhagwat et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Systematic Evaluation of the Use of Human Plasma and Serum for Mass-Spectrometry-Based Shotgun Proteomics

(2018) Jiayi Lan et al.   JOURNAL OF PROTEOME RESEARCH

Staphylococcus aureus- induced complement activation promotes tissue factor-mediated coagulation

(2018) E. W. Skjeflo et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

N-Terminomics TAILS Identifies Host Cell Substrates of Poliovirus and Coxsackievirus B3 3C Proteinases That Modulate Virus Infection

(2018) Julienne M. Jagdeo et al.   JOURNAL OF VIROLOGY

Structure of the C1r–C1s interaction of the C1 complex of complement activation

(2018) Jamal O. M. Almitairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus

(2018) Natalia Stach et al.   STRUCTURE

The Unique Cofactor Region of Zika Virus NS2B–NS3 Protease Facilitates Cleavage of Key Host Proteins

(2018) Maureen E. Hill et al.   ACS Chemical Biology

Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome

(2018) Stephanie D. Byrum et al.   JOURNAL OF PROTEOME RESEARCH

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii

(2018) Michael J. Coffey et al.   mBio

Staphylococcal serine protease–like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus

(2017) Sebastian Stentzel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sharpening Host Defenses during Infection: Proteases Cut to the Chase

(2017) Natalie C. Marshall et al.   MOLECULAR & CELLULAR PROTEOMICS

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database

(2017) Neil D Rawlings et al.   NUCLEIC ACIDS RESEARCH

N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes

(2017) Francis Impens et al.   Nature Microbiology

N-terminomics identifies widespread endoproteolysis and novel methionine excision in a genome-reduced bacterial pathogen

(2017) Iain J. Berry et al.   Scientific Reports

SrrAB Modulates Staphylococcus aureus Cell Death through Regulation ofcidABCTranscription

(2016) Ian H. Windham et al.   JOURNAL OF BACTERIOLOGY

A plasma proteolysis pathway comprising blood coagulation proteases

(2016) Lu Yang et al.   Oncotarget

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

(2016) Anna Prudova et al.   Cell Reports

Protein Termini and Their Modifications Revealed by Positional Proteomics

(2015) Giada Marino et al.   ACS Chemical Biology

IBS: an illustrator for the presentation and visualization of biological sequences: Fig. 1.

(2015) Wenzhong Liu et al.   BIOINFORMATICS

High abundant protein removal from rodent blood for biomarker discovery

(2014) Dominik R. Haudenschild et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation

(2014) Katarzyna Pustelny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annotating N Termini for the Human Proteome Project: N Termini and Nα-Acetylation Status Differentiate Stable Cleaved Protein Species from Degradation Remnants in the Human Erythrocyte Proteome

(2014) Philipp F. Lange et al.   JOURNAL OF PROTEOME RESEARCH

In VivoAssessment of Protease Dynamics in Cutaneous Wound Healing by Degradomics Analysis of Porcine Wound Exudates

(2014) Fabio Sabino et al.   MOLECULAR & CELLULAR PROTEOMICS

Impact of individual extracellular proteases onStaphylococcus aureusbiofilm formation in diverse clinical isolates and their isogenicsarAmutants

(2014) Allister J. Loughran et al.   MicrobiologyOpen

Staphylococcal Proteases Aid in Evasion of the Human Complement System

(2013) Monika Jusko et al.   Journal of Innate Immunity

Biochemical and Structural Characterization of SplD Protease from Staphylococcus aureus

(2013) Michal Zdzalik et al.   PLoS One

Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation

(2013) U. auf dem Keller et al.   Science Signaling

A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Nonessential Staphylococcus aureus Genes

(2013) P. D. Fey et al.   mBio

Staphylococcus aureusStaphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis

(2012) Alexander J Laarman et al.   EMBO JOURNAL

Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections

(2012) Molly McAdow et al.   Journal of Innate Immunity

Extracellular proteases are key mediators ofStaphylococcus aureusvirulence via the global modulation of virulence-determinant stability

(2012) Stacey L. Kolar et al.   MicrobiologyOpen

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence

(2011) Tomasz Kantyka et al.   BIOLOGICAL CHEMISTRY

The Sbi Protein Is a Multifunctional Immune Evasion Factor of Staphylococcus aureus

(2011) Emma Jane Smith et al.   INFECTION AND IMMUNITY

Staphylococcus aureus Metalloprotease Aureolysin Cleaves Complement C3 To Mediate Immune Evasion

(2011) A. J. Laarman et al.   JOURNAL OF IMMUNOLOGY

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates

(2011) Oded Kleifeld et al.   Nature Protocols

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Factor H and Factor H-Related Protein 1 Bind to Human Neutrophils via Complement Receptor 3, Mediate Attachment to Candida albicans, and Enhance Neutrophil Antimicrobial Activity

(2009) J. Losse et al.   JOURNAL OF IMMUNOLOGY

Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its cognate Staphostatin, SspC

(2009) Nicholas Nickerson et al.   MOLECULAR MICROBIOLOGY

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

The human fibrinolytic system is a target for the staphylococcal metalloprotease aureolysin

(2008) Nathalie Beaufort et al.   BIOCHEMICAL JOURNAL

Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit

(2008) Daniel J. Slade et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N-terminal fungalysin-thermolysin-propeptide domain

(2008) Nicholas N. Nickerson et al.   MOLECULAR MICROBIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens