Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

(2019) Gal Mazor et al.   Cell Death & Disease

PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways

(2019) Fang Wei et al.   CANCER LETTERS

Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway

(2019) Mingjing Shen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

(2019) Qiang Cai et al.   Molecular Cancer

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

(2019) Xinyi Tu et al.   MOLECULAR CELL

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

(2019) Graham MacLeod et al.   Cell Reports

Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2

(2019) Guo-zhong Yi et al.   BRAIN

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

(2019) Li-Chuan Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN

(2019) Bin Wang et al.   CELLULAR ONCOLOGY

LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells

(2019) Xinke Wang et al.   Cancer Cell International

Antitumor Activity of a Binary EGFR/DNA Targeting Strategy Overcomes Resistance of Glioblastoma Stem cells to Temozolomide

(2019) Zeinab Sharifi et al.   CLINICAL CANCER RESEARCH

Metformin suppresses cancer cell growth in endometrial carcinoma by inhibiting PD-L1

(2019) Jing Xue et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling

(2019) Na Wang et al.   EBioMedicine

rhEPO inhibited cell apoptosis to alleviate acute kidney injury in sepsis by AMPK/SIRT1 activated autophagy

(2019) Kan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of autophagy inhibits cadmium-triggered apoptosis in human placental trophoblasts and mouse placenta

(2019) Hua-Long Zhu et al.   ENVIRONMENTAL POLLUTION

Variability of predictive markers (hormone receptors, Her2, Ki67) and intrinsic subtypes of breast cancer in four consecutive years 2015–2018

(2019) Lidija Stevanovic et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway

(2019) Xiao Yu et al.   LIFE SCIENCES

SNAP reverses temozolomide resistance in human glioblastoma multiforme cells through down-regulation of MGMT

(2019) Chia-Kuang Tsai et al.   FASEB JOURNAL

The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling

(2019) Ruo Qiao Chen et al.   Frontiers in Oncology

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

(2018) Konrad Gabrusiewicz et al.   OncoImmunology

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

(2018) Franz L. Ricklefs et al.   Science Advances

Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

(2018) Mariachiara Buccarelli et al.   Cell Death & Disease

Chemoresistance caused by the microenvironment of glioblastoma and the corresponding solutions

(2018) Xin Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

(2018) Tor‐Christian Johannessen et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-7-5p suppresses stemness and enhances temozolomide sensitivity of drug-resistant glioblastoma cells by targeting Yin Yang 1

(2018) Bo Jia et al.   EXPERIMENTAL CELL RESEARCH

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization

(2017) Delphine Garnier et al.   NEURO-ONCOLOGY

MutL homolog 1 contributes to temozolomide-induced autophagy via ataxia-telangiectasia mutated in glioma

(2015) YUHUI ZOU et al.   Molecular Medicine Reports

Temozolomide induces autophagy via ATM-AMPK-ULK1 pathways in glioma

(2014) YUHUI ZOU et al.   Molecular Medicine Reports

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

(2013) Jessian L Munoz et al.   Molecular Therapy-Nucleic Acids

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY