Article
Nutrition & Dietetics
Ellen Wilms, Ran An, Agnieszka Smolinska, Yala Stevens, Antje R. Weseler, Montserrat Elizalde, Marie-Jose Drittij, Athanasia Ioannou, Frederik J. van Schooten, Hauke Smidt, Ad A. M. Masclee, Erwin G. Zoetendal, Daisy M. A. E. Jonkers
Summary: The study compared the fecal microbiota composition, metabolite production, immune and oxidative stress markers in prefrail elderly and younger adults, and investigated the effects of GOS supplementation in both groups. Results showed differences in microbial composition between the two age groups, with lower bifidobacteria in elderly at baseline. GOS intake increased bifidobacteria in both groups, but did not significantly impact fecal and breath metabolites, immune function, or oxidative stress markers.
CLINICAL NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Michelle Paradowska, Aleksandra Dunislawska, Maria Siwek, Anna Slawinska
Summary: Antimicrobial resistance poses an increasing threat to human and animal health, necessitating research on natural immunomodulators, such as plant extracts and probiotics. In vitro and ex vivo models offer valuable tools for experimental studies, facilitating the development of alternative antimicrobial agents.
Article
Physiology
Georgios A. Christou, Efstathios D. Pagourelias, Asterios P. Deligiannis, Evangelia J. Kouidi
Summary: The main physiological determinants of better marathon performance appear to be low BF% and RV enlargement. Upregulation of both maximum minute ventilation during exercise and haemoglobin mass may have a weaker effect to enhance marathon performance.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Rachel S. Berkowsky, Amanda L. Zaleski, Beth A. Taylor, Ming-Hui Chen, Kim M. Gans, Yin Wu, Paul M. Parducci, Yiming Zhang, Antonio B. Fernandez, Linda S. Pescatello
Summary: Caffeine has beneficial effects on firefighter job performance, but excessive intake may raise blood pressure. This study investigated the influence of caffeine, calcium, sodium, and cardiometabolic biomarkers on the blood pressure response among firefighters after intense physical exertion. The results showed that caffeine intake explained 24% of the adverse blood pressure response, while calcium and sodium intake each explained up to 24% of the blood pressure response.
Article
Physiology
Andrew S. Perrotta, Andrew T. Jeklin, Shannon S. D. Bredin, Erin M. Shellington, Kai L. Kaufman, Amanda de Faye, Rosalin M. Miles, Darren E. R. Warburton
Summary: Ultra endurance running is associated with significant impairments in cognitive performance, which are related to changes in cardiovascular function.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Physiology
Melani R. Kelly, Dawn M. Emerson, Brendon P. Mcdermott, Whitley C. Atkins, Cory L. Butts, R. Mark Laursen, Christopher Troyanos, Andrew Duckett, Jacob Siedlik
Summary: This study aimed to investigate intestinal cell injury and gastrointestinal distress symptoms among marathon runners, as well as potential risk factors. The results showed that gastrointestinal symptoms were most severe post-race, and were significantly correlated with post-race intestinal cell injury and urine specific gravity.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Physiology
Diego Moreno-Perez, Alvaro Lopez-Samanes, Mar Larrosa, Eneko Larumbe-Zabala, Aitor Centeno, Justin Roberts, Fernando Naclerio
Summary: This study compared the effects of ingesting a combined protein-carbohydrate supplement vs. a carbohydrate-only supplement on immune inflammation markers in endurance athletes after a 10-week periodized training program. The results showed that ingesting a protein-carbohydrate combined supplement promoted a more favorable immune status compared to carbohydrate-only ingestion.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Dae Hee Han, Woon-ki Kim, Cheonghoon Lee, SungJun Park, Kiuk Lee, Sung Jae Jang, GwangPyo Ko
Summary: This study investigated the effects of co-administration of L. gasseri KBL697 and IFX on colitis in mice. The results showed that the combined treatment improved inflammation symptoms, modulated inflammatory cytokine production, and affected gut microbiota and metabolic pathways.
SCIENTIFIC REPORTS
(2022)
Review
Nutrition & Dietetics
Shiqi Liu, Hengxu Liu, Li Yang, Kun Wang, Nuo Chen, Tingran Zhang, Jiong Luo
Summary: This study discusses the special needs of chronic stroke patients in rehabilitation exercise and nutrition supplement, evaluates the physiological mechanism of nutrition intervention to promote training adaptation, and compares the effects of various nutrition supplement strategies on stroke rehabilitation.
Article
Medicine, General & Internal
Ya Xu, Sophie Moore, Gaoyun Chen, Patrick Nshe, Tisbeh Faye-Joof, Andrew Prentice, Yun Yun Gong, Michael Routledge
Summary: Chronic aflatoxin exposure in early infancy in sub-Saharan Africa may have a negative impact on immune development, particularly affecting thymus growth and function.
Article
Immunology
Emilie Pollenus, Thao-Thy Pham, Leen Vandermosten, Hendrik Possemiers, Sofie Knoops, Ghislain Opdenakker, Philippe E. van den Steen
Summary: Despite efficient killing of Plasmodium parasites with antimalarial drugs, malaria complications can be lethal. Studying the resolution and healing mechanisms involved in recovery from these complications is crucial for understanding the disease progression and identifying potential treatment strategies.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Endocrinology & Metabolism
Owen Cronin, Susan A. Lanham-New, Bernard M. Corfe, Celia L. Gregson, Andrea L. Darling, Kourosh R. Ahmadi, Philippa S. Gibson, Jon H. Tobias, Kate A. Ward, Maria H. Traka, Megan Rossi, Claire Williams, Nicholas C. Harvey, Cyrus Cooper, Kevin Whelan, Andre G. Uitterlinden, Paul W. O'Toole, Claes Ohlsson, Juliet E. Compston, Stuart H. Ralston
Summary: The relationship between human microbiota and bone health is a emerging field that requires further research. Current progress supports the role of the human gut microbiome in regulating bone metabolism and the pathogenesis of osteoporosis. Further research should focus on the biological interactions between microbiota and bone metabolism.
CALCIFIED TISSUE INTERNATIONAL
(2022)
Review
Medicine, General & Internal
Mark Klingert, Pantelis T. Nikolaidis, Katja Weiss, Mabliny Thuany, Daniela Chlibkova, Beat Knechtle
Summary: This narrative review evaluates the prevalence of exercise-associated hyponatremia (EAH) among marathon runners and identifies associated risk factors. The results show that a complex interaction of different factors can cause EAH, with event-related factors such as high temperatures and person-related factors such as female sex. It is important for marathon runners to be aware of EAH and take appropriate measures for training and competition.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cell Biology
Susanne Kristine Aune, Joanna Cwikiel, Arnljot Flaa, Harald Arnesen, Svein Solheim, Ayodeji Awoyemi, Marius Troseid, Ingebjorg Seljeflot, Ragnhild Helseth
Summary: Elevated levels of gut leakage markers were observed in CAD patients after strenuous exercise, with TLR4 gene expression decreased as a possible feedback to the increase in LPS. The exercise-induced changes in gut leakage were independent of the presence of CAD.
Review
Nutrition & Dietetics
Melina Heimer, Marc Teschler, Boris Schmitz, Frank C. Mooren
Summary: The effects of probiotics on the immune system, URTI, and GI symptoms in athletes, healthy adults, and recreationally active individuals remain inconclusive. Further research is needed to draw definitive conclusions.
FRONTIERS IN NUTRITION
(2022)
Letter
Clinical Neurology
Marcos Monico-Neto, Ronaldo Vagner Thomatieli dos Santos, Hanna Karen Moreira Antunes
JOURNAL OF CLINICAL SLEEP MEDICINE
(2020)
Article
Clinical Neurology
Eduardo da Silva Alves, Ronaldo Vagner Thomatiele dos Santos, Fabio Santos de Lira, Alexandre Aparecido Almeida, Kate Edwards, Mateus Benvenutti, Sergio Tufik, Marco Tulio De Mello
Summary: The study compared the effects of different intensity acute exercise on proinflammatory and anti-inflammatory cytokines between able-bodied and spinal cord injured individuals. Results showed that interleukin - 2 was higher in SCI group, while interleukin - 4 and interleukin - 10 were lower at all collection times. Able-bodied individuals showed an increase in interleukin - 1 receptor antagonist and interleukin - 6 after exercise at certain intensities.
JOURNAL OF SPINAL CORD MEDICINE
(2021)
Article
Chemistry, Medicinal
Tatiane A. L. da Silva, Danielle C. de Medeiros, Rafaela Catherine da Silva Cunha de Medeiros, Radames M. V. Medeiros, Luanda B. F. C. de Souza, Jason A. de Medeiros, Ronaldo V. T. dos Santos, Phelipe W. de Alcantara Varela, Lucia Leite-Lais, Paulo M. S. Dantas
PHYTOTHERAPY RESEARCH
(2020)
Article
Nutrition & Dietetics
Aline Caris, Ronaldo Thomatieli-Santos
Article
Nutrition & Dietetics
Marcus V. L. dos Santos Quaresma, Camila Guazzelli Marques, Ana Carolina Oumatu Magalhaes, Ronaldo Vagner Thomatieli dos Santos
Summary: This study aimed to verify the prevalence of lifestyle factors, eating behavior dimensions, chronotype, and association with dietary practices during home confinement in Sao Paulo, Brazil, amid the COVID-19 pandemic. Results indicated that emotional eating and binge eating were positively correlated, while dietary practices were negatively correlated with binge eating, emotional eating, and body mass index. Various factors such as eating behavior, exercise practice, sleep quality, and social status were found to be predictors of dietary practices during the social confinement period.
Article
Biochemistry & Molecular Biology
Marcus V. L. Dos Santos Quaresma, Raquel Campos, Edgar Tavares-Silva, Camila Guazzelli Marques, Ronaldo Vagner Thomatieli-Santos
Summary: The study showed that caffeine supplementation can decrease fatigue and increase vigor perception post-exercise. Levels of IL-10 were higher in the caffeine group 1 hour after exercise, suggesting a potential association between IL-10 and reduced post-exercise fatigue perception.
Review
Nutrition & Dietetics
Camila Guazzelli Marques, Marcus V. L. dos Santos Quaresma, Fernanda Patti Nakamoto, Ana Carolina Oumatu Magalhaes, Glaice Aparecida Lucin, Ronaldo Vagner Thomatieli-Santos
Summary: Modern lifestyle factors such as physical inactivity, Western diet, and poor sleep quality play a key role in positive energy balance, leading to adipose tissue hypertrophy and dysfunction. The interaction between lifestyle factors and tissue metabolic dysfunction can increase chronic systemic inflammation, resulting in insulin resistance and other metabolic disorders.
FRONTIERS IN NUTRITION
(2021)
Review
Physiology
Andre Luis Araujo Minari, Ronaldo Thomatieli-Santos
Summary: Macrophages play a crucial role in tissue homeostasis and muscle recovery. There are two major subsets of macrophages: proliferative and restorative, which contribute to myogenic cell proliferation and mature muscle myogenesis, respectively.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2022)
Article
Environmental Sciences
Fabio Santos Lira, Telmo Pereira, Luciele Guerra Minuzzi, Caique Figueiredo, Tiago Olean-Oliveira, Ana Paula Coelho Figueira Freire, Manuel Joao Coelho-e-Silva, Armando Caseiro, Ronaldo Vagner Thomatieli-Santos, Vanessa Ribeiro Dos Santos, Luis Alberto Gobbo, Marilia Seelaender, Karsten Krueger, Ricardo Aurino Pinho, Jose Cesar Rosa-Neto, Bruna Spolador de Alencar Silva
Summary: This study aims to address gaps in scientific knowledge on COVID-19 by conducting a prospective observational cohort study focused on immune, inflammatory, and metabolic markers, as well as clinical and mental health. It will explore the effects of physical activity and body composition on individual trajectories. Mechanistic evidence will be provided through in-vitro assays, analyzing the potential long-term benefits on mental and cardiovascular health.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Helton de Sa Souza, Camila Maria de Melo, Ronaldo Delmonte Piovezan, Rafael Eduardo Eustorgio Pinheiro Chagas Miranda, Miguel Araujo Carneiro-Junior, Bruno Moreira Silva, Ronaldo Vagner Thomatieli-Santos, Sergio Tufik, Dalva Poyares, Vania D'Almeida
Summary: A study found that resistance exercise training can improve sleep and inflammation status in sarcopenic patients, possibly by increasing anti-inflammatory markers.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Food Science & Technology
Andressa Roehrig Volpe-Fix, Elias de Franca, Jean Carlos Silvestre, Ronaldo Vagner Thomatieli-Santos
Summary: Food bioactive compounds (FBC) are substances found in fruits, vegetables, and other sources that have physiological effects on individuals who consume them. Some FBCs, such as polyphenols, have antioxidant and anti-inflammatory properties. This review explores the effects of supplementing with various polyphenols on oxidative stress and post-exercise inflammation markers. The findings suggest that cocoa, green tea extract, and curcumin can help alleviate cell damage and inflammation caused by exercise, but conflicting results are found for anthocyanins, quercetins, and resveratrol. The impact of simultaneously supplementing multiple FBCs is also discussed.
Article
Sport Sciences
Luis Branquinho, Pedro Forte, Ronaldo V. Thomatieli-Santos, Elias de Franca, Daniel A. Marinho, Jose E. Teixeira, Ricardo Ferraz
Summary: This study analyzes the potential impact of changing the date and weather conditions of the World Cup on players' performance and finds that despite changes in the schedule, the performance of the players was not significantly affected. Additionally, patterns in the behavior of teams that excelled in the later stages of the competition were identified.