Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

Diatom fucan polysaccharide precipitates carbon during algal blooms

(2021) Silvia Vidal-Melgosa et al.   Nature Communications

Scaling diffraction data in the DIALS software package: algorithms and new approaches for multi-crystal scaling

(2020) James Beilsten-Edmands et al.   Acta Crystallographica Section D-Structural Biology

RTX Adhesins are Key Bacterial Surface Megaproteins in the Formation of Biofilms

(2019) Shuaiqi Guo et al.   TRENDS IN MICROBIOLOGY

Structure and functional analysis of a bacterial adhesin sugar-binding domain

(2019) Tyler D. R. Vance et al.   PLoS One

Editorial: Lectins and Their Ligands in Shaping Immune Responses

(2019) Bernd Lepenies et al.   Frontiers in Immunology

Conserved structural features anchor biofilm-associated RTX-adhesins to the outer membrane of bacteria

(2018) Shuaiqi Guo et al.   FEBS Journal

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

(2018) Vasilios Kalas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemistry-Driven Glycoscience

(2018) Laura L. Kiessling   BIOORGANIC & MEDICINAL CHEMISTRY

The neoglycolipid (NGL) technology-based microarrays and future prospects

(2018) Zhen Li et al.   FEBS LETTERS

Structural elucidation of fucoidan from Cladosiphon okamuranus (Okinawa mozuku)

(2018) Seng Joe Lim et al.   FOOD CHEMISTRY

Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets

(2018) Maximilian M. Sauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn’s disease

(2017) Laurel K. Mydock-McGrane et al.   Expert Opinion on Drug Discovery

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

(2017) Caitlin N. Spaulding et al.   NATURE

Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice

(2017) Shuaiqi Guo et al.   Science Advances

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins

(2016) Francesco S. Ielasi et al.   mBio

A New Versatile Microarray-based Method for High Throughput Screening of Carbohydrate-active Enzymes

(2015) Silvia Vidal-Melgosa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms

(2015) Bruno Gügi et al.   Marine Drugs

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Monoclonal Antibodies Directed to Fucoidan Preparations from Brown Algae

(2015) Thomas A. Torode et al.   PLoS One

Convergent and divergent mechanisms of sugar recognition across kingdoms

(2014) Maureen E Taylor et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The role of carbohydrate recognition during human sperm-egg binding

(2013) G. F. Clark   HUMAN REPRODUCTION

A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131

(2013) Makrina Totsika et al.   JOURNAL OF INFECTIOUS DISEASES

Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation

(2013) Marcel Tutor Ale et al.   RSC Advances

Targeting the bacteria–host interface

(2013) Anne Marie Krachler et al.   Virulence

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Re-Evaluation of a Bacterial Antifreeze Protein as an Adhesin with Ice-Binding Activity

(2012) Shuaiqi Guo et al.   PLoS One

Structural basis for promiscuity and specificity during Candida glabrata invasion of host epithelia

(2012) M. Maestre-Reyna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycan Microarrays for Decoding the Glycome

(2011) Cory D. Rillahan et al.   Annual Review of Biochemistry

Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors

(2011) C. K. Cusumano et al.   Science Translational Medicine

Evolutionary Forces Shaping the Golgi Glycosylation Machinery: Why Cell Surface Glycans Are Universal to Living Cells

(2011) A. Varki   Cold Spring Harbor Perspectives in Biology

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 β-glucosidase fromKluyveromyces marxianus

(2010) Erina Yoshida et al.   BIOCHEMICAL JOURNAL

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of flocculin-mediated social behavior in yeast

(2010) M. Veelders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antifreeze Protein in Antarctic Marine Diatom, Chaetoceros neogracile

(2009) In Gyu Gwak et al.   MARINE BIOTECHNOLOGY

How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation

(2008) H GILBERT et al.   CURRENT OPINION IN PLANT BIOLOGY

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY

Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex

(2008) Adinda Wellens et al.   PLoS One