Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis

Yansuanmalingua inhibits replication of type 2 porcine reproductive and respiratory syndrome virus via activating the caspase-8 apoptosis pathway

(2020) Yaozhong Ding et al.   JOURNAL OF BASIC MICROBIOLOGY

In vitro screening antiviral activity of Thai medicinal plants against porcine reproductive and respiratory syndrome virus

(2020) Chaiwat Arjin et al.   BMC Veterinary Research

A recombination between two Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV‐1) vaccine strains has caused severe outbreaks in Danish pigs

(2020) Lise Kirstine Kvisgaard et al.   Transboundary and Emerging Diseases

Evolutionary and recombination analysis of porcine reproductive and respiratory syndrome isolates in China

(2020) Zhendong Zhang et al.   VIRUS GENES

Genetic Diversity of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) From 1996 to 2017 in China

(2020) Yifeng Jiang et al.   Frontiers in Microbiology

Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov

(2020) Haiping Zhang et al.   Interdisciplinary Sciences-Computational Life Sciences

Novel lineage 1 recombinants of porcine reproductive and respiratory syndrome virus isolated from vaccinated herds: genome sequences and cytokine production profiles

(2020) Jonghyun Park et al.   ARCHIVES OF VIROLOGY

Porcine reproductive and respiratory syndrome virus: phylogenetic analysis of circulating strains in the Republic of Ireland from 2016 to 2017

(2020) Rose M. Fitzgerald et al.   ARCHIVES OF VIROLOGY

Discovering small-molecule therapeutics against SARS-CoV-2

(2020) Vaibhav Tiwari et al.   DRUG DISCOVERY TODAY

High genetic diversity of Chinese porcine reproductive and respiratory syndrome viruses from 2016 to 2019

(2020) Nanhua Chen et al.   RESEARCH IN VETERINARY SCIENCE

Porcine reproductive and respiratory syndrome virus dissemination across pig production systems in the United States

(2020) Manuel Jara et al.   Transboundary and Emerging Diseases

Small molecules block the interaction between porcine reproductive and respiratory syndrome virus and CD163 receptor and the infection of pig cells

(2020) Chang Huang et al.   Virology Journal

Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells

(2020) Chao Yang et al.   VIRUS RESEARCH

The emergence of a novel recombinant porcine reproductive and respiratory syndrome virus with an amino acid insertion in GP5 protein

(2020) Zhongbao Song et al.   MICROBIAL PATHOGENESIS

Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro

(2020) Xiao Liu et al.   VETERINARY MICROBIOLOGY

Overexpression of RACK1 enhanced the replication of porcine reproductive and respiratory syndrome virus in Marc-145 cells and promoted the NF-κB activation via upregulating the expression and phosphorylation of TRAF2

(2019) Xiao Liu et al.   GENE

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications

(2019) Christian Bailly   PHYTOMEDICINE

Development of Small-Molecule Inhibitors Against Zika Virus Infection

(2019) Lili Wang et al.   Frontiers in Microbiology

In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification

(2018) Lingyun Zhu et al.   BMC Veterinary Research

RACK1 is indispensable for porcine reproductive and respiratory syndrome virus replication and NF-κB activation in Marc-145 cells

(2018) Junlong Bi et al.   Scientific Reports

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

(2018) Rachel H. Clare et al.   Nature Communications

Reduction of infection by inhibiting mTOR pathway is associated with reversed repression of type I interferon by porcine reproductive and respiratory syndrome virus

(2017) Qinfang Liu et al.   JOURNAL OF GENERAL VIROLOGY

Alterations in the host transcriptome in vitro following Rift Valley fever virus infection

(2017) Chelsea Pinkham et al.   Scientific Reports

Inhibitory effects of LiCl on replication of type II porcine reproductive and respiratory syndrome virus in vitro

(2015) Jin Cui et al.   ANTIVIRAL THERAPY

Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation

(2014) Zhanzhong Zhao et al.   BIOCHEMICAL PHARMACOLOGY

Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome virus (PRRSV) replication

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Identification of porcine reproductive and respiratory syndrome virus inhibitors through an oriented screening on natural products

(2013) Wen-gui Li et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Integrins modulate the infection efficiency of West Nile virus into cells

(2013) K. Schmidt et al.   JOURNAL OF GENERAL VIROLOGY

In Vitro Screening for Compounds Derived from Traditional Chinese Medicines with Antiviral Activities Against Porcine Reproductive and Respiratory Syndrome Virus

(2013) Jia Cheng   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus

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