Single-cell deconstruction of stem-cell-driven schistosome development

Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate

(2021) Pengyang Li et al.   Nature Communications

Concomitant Immunity and Worm Senescence May Drive Schistosomiasis Epidemiological Patterns: An Eco-Evolutionary Perspective

(2020) Julia C. Buck et al.   Frontiers in Immunology

Schistosome migration in the definitive host

(2020) Catherine S. Nation et al.   PLoS Neglected Tropical Diseases

The esophageal gland mediates host immune evasion by the human parasiteSchistosoma mansoni

(2020) Jayhun Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni

(2020) Carmen Lidia Diaz Soria et al.   Nature Communications

Systematically improved in vitro culture conditions reveal new insights into the reproductive biology of the human parasite Schistosoma mansoni

(2019) Jipeng Wang et al.   PLOS BIOLOGY

Self-assembling manifolds in single-cell RNA sequencing data

(2019) Alexander J Tarashansky et al.   eLife

Prospectively Isolated Tetraspanin + Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration

(2018) An Zeng et al.   CELL

Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq

(2018) Shristi Pandey et al.   CURRENT BIOLOGY

Cell type transcriptome atlas for the planarianSchmidtea mediterranea

(2018) Christopher T. Fincher et al.   SCIENCE

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

(2018) Mireya Plass et al.   SCIENCE

Nanomedicine Approaches Against Parasitic Worm Infections

(2018) Pengyang Li et al.   Advanced Healthcare Materials

Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni

(2018) Bo Wang et al.   eLife

Flatworm-specific transcriptional regulators promote the specification of tegumental progenitors in Schistosoma mansoni

(2018) George R Wendt et al.   eLife

The Cellular and Molecular Basis for Planarian Regeneration

(2018) Peter W. Reddien   CELL

Causes and evolutionary consequences of primordial germ-cell specification mode in metazoans

(2017) Carrie A. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

(2017) John D. Chan et al.   Nature Communications

Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

(2017) Robert Bergquist et al.   Infectious Diseases of Poverty

Schistosomiasis as a disease of stem cells

(2016) George R Wendt et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

NF-YB Regulates Spermatogonial Stem Cell Self-Renewal and Proliferation in the Planarian Schmidtea mediterranea

(2016) Harini Iyer et al.   PLoS Genetics

The evolutionary origin of bilaterian smooth and striated myocytes

(2016) Thibaut Brunet et al.   eLife

Two FGFRL-Wnt circuits organize the planarian anteroposterior axis

(2016) M Lucila Scimone et al.   eLife

Stem cell progeny contribute to the schistosome host-parasite interface

(2016) James J Collins et al.   eLife

Evolution: A Turn Up for the Worms

(2015) D.T.J. Littlewood et al.   CURRENT BIOLOGY

Reduced transmission of human schistosomiasis after restoration of a native river prawn that preys on the snail intermediate host

(2015) Susanne H. Sokolow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ancestral gene repertoire of animal stem cells

(2015) Alexandre Alié et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Schistosome Esophagus Is a ‘Hotspot’ for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing

(2015) R. Alan Wilson et al.   PLoS Neglected Tropical Diseases

Nuclear genomic signals of the ‘microturbellarian’ roots of platyhelminth evolutionary innovation

(2015) Christopher E Laumer et al.   eLife

Halting harmful helminths

(2014) K. F. Hoffmann et al.   SCIENCE

Adult somatic stem cells in the human parasite Schistosoma mansoni

(2013) James J. Collins III et al.   NATURE

The genomes of four tapeworm species reveal adaptations to parasitism

(2013) Isheng J. Tsai et al.   NATURE

Muscle Cells Provide Instructions for Planarian Regeneration

(2013) Jessica N. Witchley et al.   Cell Reports

Closing the circle of germline and stem cells: the Primordial Stem Cell hypothesis

(2013) Jordi Solana   EvoDevo

The Schistosome Oesophageal Gland: Initiator of Blood Processing

(2013) Xiao-Hong Li et al.   PLoS Neglected Tropical Diseases

It's No Fluke: The Planarian as a Model for Understanding Schistosomes

(2013) James J. Collins et al.   PLoS Pathogens

Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

(2013) Bo Wang et al.   eLife

Praziquantel treatment of school children from single and mixed infection foci of intestinal and urogenital schistosomiasis along the Senegal River Basin: monitoring treatment success and re-infection patterns

(2012) Bonnie L. Webster et al.   ACTA TROPICA

Whole-genome sequence of Schistosoma haematobium

(2012) Neil D Young et al.   NATURE GENETICS

Macroparasite Life Histories

(2011) Mark Viney et al.   CURRENT BIOLOGY

Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni

(2011) Kathrin K. Geyer et al.   Nature Communications

An Atlas for Schistosoma mansoni Organs and Life-Cycle Stages Using Cell Type-Specific Markers and Confocal Microscopy

(2011) James J. Collins et al.   PLoS Neglected Tropical Diseases

A conserved germline multipotency program

(2010) C. E. Juliano et al.   DEVELOPMENT

The embryonic development of Schistosoma mansoni eggs: proposal for a new staging system

(2009) Arnon D. Jurberg et al.   DEVELOPMENT GENES AND EVOLUTION

The Schistosoma japonicum genome reveals features of host–parasite interplay

(2009)   NATURE

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs

(2009) M. J. DOENHOFF et al.   PARASITOLOGY

The saga of schistosome migration and attrition

(2009) R. A. WILSON   PARASITOLOGY

Schistosomiasis in Africa: An Emerging Tragedy in Our New Global Health Decade

(2009) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases