Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment

Inter-individual Variability in Activity of the Major Drug Metabolizing Enzymes in Liver Homogenates of 20 Individuals

(2018) Shalenie P. den Braver-Sewradj et al.   CURRENT DRUG METABOLISM

High-performance liquid chromatography-based assay for glutathione transferase theta 2 activity: Application to characterize interindividual variability in human liver fractions

(2018) Yongjie Zhang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strains

(2018) Yu-Syuan Luo et al.   TOXICOLOGY

Analytical methods impact estimates of trichloroethylene’s glutathione conjugation and risk assessment

(2018) Fagen Zhang et al.   TOXICOLOGY LETTERS

Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse

(2017) Yu-Syuan Luo et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation

(2016) Stefan J. Dekker et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Simulation of interindividual differences in inactivation of reactive para -benzoquinone imine metabolites of diclofenac by glutathione S -transferases in human liver cytosol

(2016) Michiel W. den Braver et al.   TOXICOLOGY LETTERS

Cytochrome P450-Mediated Bioactivation of Mefenamic Acid to Quinoneimine Intermediates and Inactivation by Human Glutathione S-Transferases

(2014) Harini Venkataraman et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard

(2013) Ivan Rusyn et al.   PHARMACOLOGY & THERAPEUTICS

Potential of the NBP Method for the Study of Alkylation Mechanisms: NBP as a DNA-Model

(2012) Rafael Gómez-Bombarelli et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Globin Monoadducts and Cross-Links Provide Evidence for the Presence of S-(1,2-Dichlorovinyl)-l-cysteine Sulfoxide, Chlorothioketene, and 2-Chlorothionoacetyl Chloride in the Circulation in Rats Administered S-(1,2-Dichlorovinyl)-l-cysteine

(2009) Nella Barshteyn et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine

(2009) Sungkyoon Kim et al.   TOXICOLOGY

Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-l-cysteine

(2009) Sungkyoon Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY