CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function

Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

(2020) Keisuke Yanagida et al.   DEVELOPMENTAL CELL

Illuminating G-Protein-Coupling Selectivity of GPCRs

(2019) Asuka Inoue et al.   CELL

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation

(2018) Elisabetta Argenzio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The balance between Gαi-Cdc42/Rac and Gα12/13-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate

(2017) Nathalie R. Reinhard et al.   MOLECULAR BIOLOGY OF THE CELL

Identification and Characterization of a Bacterial Homolog of Chloride Intracellular Channel (CLIC) Protein

(2017) Shubha Gururaja Rao et al.   Scientific Reports

Emerging biological roles of Cl−intracellular channel proteins

(2016) Elisabetta Argenzio et al.   JOURNAL OF CELL SCIENCE

The chloride intracellular channel 5A stimulates podocyte Rac1, protecting against hypertension-induced glomerular injury

(2016) Mahtab Tavasoli et al.   KIDNEY INTERNATIONAL

S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness

(2015) A. Chavez et al.   JOURNAL OF CELL SCIENCE

A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways

(2015) Sandra Lecat et al.   MOLECULAR & CELLULAR PROTEOMICS

Involvement of Local Lamellipodia in Endothelial Barrier Function

(2015) Jerome W. Breslin et al.   PLoS One

Members of the Chloride Intracellular Ion Channel Protein Family Demonstrate Glutaredoxin-Like Enzymatic Activity

(2015) Heba Al Khamici et al.   PLoS One

Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery

(2014) John C Edwards et al.   BMC Nephrology

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Point Mutations in the Transmembrane Region of the Clic1 Ion Channel Selectively Modify Its Biophysical Properties

(2013) Stefania Averaimo et al.   PLoS One

Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors

(2011) Victoria A. Blaho et al.   CHEMICAL REVIEWS

The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

(2010) Dene R. Littler et al.   FEBS LETTERS

Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene

(2010) Min Ru Qiu et al.   GENESIS

Chloride Intracellular Channel Protein-4 Functions in Angiogenesis by Supporting Acidification of Vacuoles Along the Intracellular Tubulogenic Pathway

(2009) Barbara Ulmasov et al.   AMERICAN JOURNAL OF PATHOLOGY

Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro

(2009) Jennifer J. Tung et al.   ANGIOGENESIS

Chloride Intracellular Channel-4 Is a Determinant of Native Collateral Formation in Skeletal Muscle and Brain

(2009) Dan Chalothorn et al.   CIRCULATION RESEARCH

S100A4 and Bone Morphogenetic Protein-2 Codependently Induce Vascular Smooth Muscle Cell Migration via Phospho–Extracellular Signal-Regulated Kinase and Chloride Intracellular Channel 4

(2009) Edda Spiekerkoetter et al.   CIRCULATION RESEARCH

Spatiotemporal Regulation of Chloride Intracellular Channel Protein CLIC4 by RhoA

(2009) Bas Ponsioen et al.   MOLECULAR BIOLOGY OF THE CELL

Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices

(2009) Kayla J Bayless et al.   Nature Protocols

CLIC4 interacts with histamine H3 receptor and enhances the receptor cell surface expression

(2008) Kay Maeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS