标题
QSER1 protects DNA methylation valleys from de novo methylation
作者
关键词
-
出版物
SCIENCE
Volume 372, Issue 6538, Pages eabd0875
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-04-10
DOI
10.1126/science.abd0875
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation
- (2019) Qing V. Li et al. NATURE GENETICS
- A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice
- (2019) Gintarė Sendžikaitė et al. Nature Communications
- The diverse roles of DNA methylation in mammalian development and disease
- (2019) Maxim V. C. Greenberg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA Methylation: Shared and Divergent Features across Eukaryotes
- (2019) Robert J. Schmitz et al. TRENDS IN GENETICS
- EGR1 recruits TET1 to shape the brain methylome during development and upon neuronal activity
- (2019) Zhixiong Sun et al. Nature Communications
- Impact of epigenetics in aging and age related neurodegenerative diseases
- (2018) Omkaram Gangisetty Frontiers in Bioscience-Landmark
- De novo apparent loss-of-function mutations in PRR12 in three patients with intellectual disability and iris abnormalities
- (2018) Magalie S. Leduc et al. HUMAN GENETICS
- Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome
- (2018) Shiro Tara et al. BLOOD
- Identification of Novel Candidate Markers of Type 2 Diabetes and Obesity in Russia by Exome Sequencing with a Limited Sample Size
- (2018) Yury Barbitoff et al. Genes
- Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions
- (2018) Patricia Heyn et al. NATURE GENETICS
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells
- (2017) Nipun Verma et al. NATURE GENETICS
- Dynamic epigenomic landscapes during early lineage specification in mouse embryos
- (2017) Yu Zhang et al. NATURE GENETICS
- TET-mediated active DNA demethylation: mechanism, function and beyond
- (2017) Xiaoji Wu et al. NATURE REVIEWS GENETICS
- Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes
- (2016) Zengrong Zhu et al. Cell Stem Cell
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations
- (2016) Dali Han et al. MOLECULAR CELL
- TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling
- (2016) Hai-Qiang Dai et al. NATURE
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Epigenetics and Human Disease
- (2016) Huda Y. Zoghbi et al. Cold Spring Harbor Perspectives in Biology
- Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer
- (2016) Stephan H. Bernhart et al. Scientific Reports
- ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
- (2015) Guangchuang Yu et al. BIOINFORMATICS
- Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution
- (2015) Yonatan Stelzer et al. CELL
- Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation
- (2015) Laura Wiehle et al. MOLECULAR AND CELLULAR BIOLOGY
- Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
- (2015) Jing Liao et al. NATURE GENETICS
- FBXL10 protects Polycomb-bound genes from hypermethylation
- (2015) Mathieu Boulard et al. NATURE GENETICS
- A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations
- (2015) Carlos Córdova-Fletes et al. NEUROGENETICS
- Epigenomic evolution in diffuse large B-cell lymphomas
- (2015) Heng Pan et al. Nature Communications
- PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells
- (2015) Partha Pratim Das et al. Cell Reports
- An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells
- (2014) Federico González et al. Cell Stem Cell
- Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells
- (2014) Meelad M. Dawlaty et al. DEVELOPMENTAL CELL
- Role of Tet proteins in enhancer activity and telomere elongation
- (2014) Falong Lu et al. GENES & DEVELOPMENT
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
- (2013) Wei Xie et al. CELL
- A double take on bivalent promoters
- (2013) P. Voigt et al. GENES & DEVELOPMENT
- Modification of Enhancer Chromatin: What, How, and Why?
- (2013) Eliezer Calo et al. MOLECULAR CELL
- NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
- (2013) Yael Costa et al. NATURE
- Large conserved domains of low DNA methylation maintained by Dnmt3a
- (2013) Mira Jeong et al. NATURE GENETICS
- DNA methylation: roles in mammalian development
- (2013) Zachary D. Smith et al. NATURE REVIEWS GENETICS
- Coordinate Regulation of DNA Methylation and H3K27me3 in Mouse Embryonic Stem Cells
- (2013) James A. Hagarman et al. PLoS One
- Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
- (2013) Hannah K Long et al. eLife
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Architecture of the human regulatory network derived from ENCODE data
- (2012) Mark B. Gerstein et al. NATURE
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
- (2011) Felix Krueger et al. BIOINFORMATICS
- Fast and accurate long-read alignment with Burrows–Wheeler transform
- (2010) Heng Li et al. BIOINFORMATICS
- Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
- (2010) V. K. Rakyan et al. GENOME RESEARCH
- Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
- (2010) Chun-Xiao Song et al. NATURE BIOTECHNOLOGY
- Charting histone modifications and the functional organization of mammalian genomes
- (2010) Vicky W. Zhou et al. NATURE REVIEWS GENETICS
- Genomewide association study for onset age in Parkinson disease
- (2009) Jeanne C Latourelle et al. BMC Medical Genetics
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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