Advanced Biotechnologies: Collections of Plant Cell Cultures As a Basis for Development and Production of Medicinal Preparations

The review examines the principles in formation of cell culture and tissue collections of higher plants in vitro as a variant of genetic collections, the modern state and perspective of using collections in studies of the peculiarities and patterns of synthesis of biologically active substances of higher plants, the important role of collections in biotechnological production of substances for medicinal preparations, and methods for maintaining the stability of cell cultures during long-term cultivation. Particular attention is paid to the retrospective and current state of the All-Russia Collection of Cell Cultures of Higher Plants, the founder of which was Russian Academy of Sciences Corresponding Member R.G. Butenko.

Automated summary

This review focuses on the principles of formation of cell culture and tissue collections of higher plants, and their modern state and perspective in studying the synthesis of biologically active substances. It also highlights the important role of collections in biotechnological production of medicinal preparations and methods for maintaining stability in cell cultures.