Article
Psychiatry
Yael Pikkel Igal, Irit Meretyk, Aziz Darawshe, Samer Hayek, Limor Givon, Avi Levy, Idan Sipori, Yonatan Nuriel, Boaz Bloch, Shraga Buniak, Ron Eshel, Eyal Fruchter
Summary: During the COVID-19 pandemic, psychiatric emergency department (ED) visits decreased by 30% along with the overall ED visits, with an increase in the proportion of anxiety disorders, personality disorders, psychosis, and post-traumatic stress disorder referrals. Meanwhile, the proportions of adjustment disorder and consultation regarding observation decreased.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Emergency Medicine
Stephanie Stroever, Chelsea Brett, Katherine Michael, Joann Petrini
Summary: This study found that the proportion of emergency department encounters attributed to mental health conditions increased after the COVID-19 outbreak. Substance abuse, anxiety, and mood disorders were the main types of mental health diagnoses. Emergency departments play a crucial role in identifying and triaging mental health emergencies, especially during disasters and extended crises.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Mattia Bellan, Francesco Gavelli, Eyal Hayden, Filippo Patrucco, Daniele Soddu, Anita R. Pedrinelli, Micol G. Cittone, Eleonora Rizzi, Giuseppe F. Casciaro, Veronica Vassia, Raffaella Landi, Mirta Menegatti, Maria L. Gastaldello, Michela Beltrame, Emanuela Labella, Stelvio Tonello, Gian C. Avanzi, Mario Pirisi, Luigi M. Castello, Pier P. Sainaghi
Summary: The COVID-19 pandemic has drastically reduced the number of ED referrals in Italy, leading to an increased hospital admission rate and a shift towards higher priority codes for admissions. There has been a significant decrease in referrals for both traumatic and non-traumatic conditions, with suspected COVID-19 accounting for a large portion of non-traumatic cases.
Article
Emergency Medicine
Javier Alejandro Lecca Espinoza, Jorge Elias Junior, Carlos Henrique Miranda
Summary: This case report describes a 50-year-old woman who presented to the emergency department with abdominal pain, febrile hepatosplenomegaly, and was ultimately diagnosed with suprahepatic vein thrombosis secondary to COVID-19. Initially, the patient was not placed in a private room due to the atypical presentation, leading to a COVID-19 outbreak in the emergency department.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Review
Health Care Sciences & Services
Ioannis Pantazopoulos, Stamatoula Tsikrika, Stavroula Kolokytha, Emmanouil Manos, Konstantinos Porpodis
Summary: COVID-19 is an emerging global public health concern that has led to the restructuring of emergency care delivery in hospitals. The overwhelming volume of published papers each week has made it challenging for emergency physicians to keep up with the ever-changing information. This review aims to provide emergency physicians with a summary of the current literature on managing COVID-19 patients in the emergency department.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Pediatrics
Laura Cesca, Ester Conversano, Federica Alessandra Vianello, Laura Martelli, Chiara Gualeni, Francesca Bassani, Milena Brugnara, Giulia Rubin, Mattia Parolin, Mauro Anselmi, Mara Marchiori, Gianluca Vergine, Elisabetta Miorin, Enrico Vidal, Cristina Milocco, Cecilia Orsi, Giuseppe Puccio, Licia Peruzzi, Giovanni Montini, Roberto Dall'Amico
Summary: The first wave of the Covid-19 pandemic significantly impacted the management of febrile UTIs in pediatric emergency departments, resulting in a decrease in cases seen in the ED but with higher clinical severity. Children with febrile UTIs during this period were more severely ill, likely due to delayed access caused by fears of potential hospital-acquired Sars-Cov-2 infection. The potential increase in kidney scarring in this population should be taken into consideration.
Article
Emergency Medicine
Arjun K. Venkatesh, Alexander T. Janke, Li Shu-Xia, Craig Rothenberg, Pawan Goyal, Aisha Terry, Michelle Lin
Summary: This study used a national emergency medicine clinical quality registry to describe recent trends in ED visitation during the pandemic, revealing a significant initial decline followed by some recovery, but still below pre-pandemic levels. The proportion of visits for select emergency conditions increased early in the pandemic, yet visits for acute myocardial infarction and cerebrovascular disease remained lower in 2020 compared to 2019. Despite variation in the trajectory of the COVID-19 outbreak, the overall pattern of ED visits was similar across regions and time.
ANNALS OF EMERGENCY MEDICINE
(2021)
Article
Multidisciplinary Sciences
Nicholas M. Mohr, Anusha Krishnadasan, Karisa K. Harland, Patrick Ten Eyck, William R. Mower, Walter A. Schrading, Juan Carlos C. Montoy, L. Clifford McDonald, Preeta K. Kutty, Elisabeth Hesse, Scott Santibanez, David N. Weissman, Patricia Slev, David A. Talan
Summary: The risk of SARS-CoV-2 infection was similar for unvaccinated U.S. emergency department healthcare personnel compared to nonclinical staff and healthcare personnel engaged in direct patient care. Many identified risk factors were related to community exposures.
Article
Pediatrics
Lorenzo Di Sarno, Antonietta Curatola, Giorgio Conti, Marcello Covino, Chiara Bertolaso, Antonio Chiaretti, Antonio Gatto
Summary: This study analyzed the impact of the COVID-19 pandemic and lockdown measures on Pediatric Emergency Department (ED) admission for acute wheezing. The results showed a significant drop in the number of pediatric ED admissions for acute wheezing during the COVID-19 outbreak, possibly due to a reduction in the circulation of common respiratory viruses and reduced exposure to aeroallergens.
PEDIATRIC PULMONOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Pei-Ying Lin, Warren Kaplan, Chia-Hung Lin, Yen-Han Lee
Summary: Taiwan's NHI is a universal healthcare system that has received widespread acclaim, but it has faced challenges in recent years, including excessive hospital visits, a lack of primary care and referral system, and high turnover rate of healthcare workers. This review highlights the major problems and recommendations for policies such as strengthening primary care services, reducing turnover rate, and increasing premiums and copayments. The aim is to provide policymakers and scholars with a clinical perspective on the merits and critical issues of NHI.
PUBLIC HEALTH NURSING
(2023)
Article
Health Care Sciences & Services
Yong-Seok Kim, In-Byung Kim, Seon-Rye Kim, Byung-Jun Cho
Summary: Severe patients visited emergency centers more frequently during the COVID-19 period, leading to a higher rate of admission to the intensive care unit or death. After COVID-19, the total number of emergency department visits decreased, but the length of stay for severely ill patients and the utilization rate of ambulances increased.
Article
Emergency Medicine
Brian J. Yun, Yosef Berlyand, Joshua J. Baugh, Andy Hung-Yi Lee, Stephen Dorner, Susan R. Wilcox, Ali S. Raja
Summary: The study aimed to create a COVID-19 observation protocol for the ED observation unit (EDOU) to facilitate data collection and timely intervention for patients with mild to moderate COVID-19, and to prevent clinical deterioration.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
David Lanham, Jennifer Roe, Alisha Chauhan, Rebecca Evans, Toby Hillman, Sarah Logan, Melissa Heightman
Summary: The study highlighted the importance of safety-netting and appropriate follow-up services for discharged COVID-19 infected patients. Telephone follow-up identified patients needing urgent recall and face-to-face review for persistent symptoms. A COVID-19 follow-up clinic was established to provide multi-professional assessment and diagnostics for these patients.
Article
Pediatrics
Barbara H. Chaiyachati, Joanne N. Wood, Camille Carter, Daniel M. Lindberg, Thomas H. Chun, Lawrence J. Cook, Elizabeth R. Alpern
Summary: This study aimed to determine the change in the rate of emergency department encounters related to child physical abuse during the COVID-19 pandemic in the United States. The results showed that the encounter rates for child physical abuse decreased, with the greatest reductions observed in preschool and school-aged children and lower-severity encounters. Further evaluation is needed to clarify whether these reductions reflect true decreases or decreased recognition of child physical abuse.
Article
Public, Environmental & Occupational Health
Royal K. Law, Amy F. Wolkin, Nimesh Patel, Alen Alic, Keming Yuan, Kamran Ahmed, Nimi Idaikkadar, Tadesse Haileyesus
Summary: This study examines the trends of injury-related emergency department visits in the U.S. before and during the COVID-19 pandemic. The findings show a significant decrease in nonfatal injury-related emergency department visits during April through June 2020 compared to the same period in 2019. Similar decreases were observed for motor vehicle-related injuries and falls-related injuries. However, emergency department visits for self-harm, assault, and poisoning remained relatively stable.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Fausto Rosa, Marcello Covino, Andrea Russo, Sara Salini, Raffaele Forino, Davide Della Polla, Pietro Fransvea, Giuseppe Quero, Claudio Fiorillo, Antonio La Greca, Gabriele Sganga, Antonio Gasbarrini, Francesco Franceschi, Sergio Alfieri
Summary: In a prospective observational cohort study, the frailty status of patients at the emergency department admission was evaluated for predicting in-hospital death risk stratification for those needing urgent cholecystectomy. Frailty and open surgery were found to be independent predictors of major complications. The evaluation of functional status in the emergency department could predict the risk of major complications and the need for open surgical approach in elderly patients undergoing urgent cholecystectomy.
DIGESTIVE AND LIVER DISEASE
(2023)
Article
Medicine, Legal
Francesca Cittadini, Giovanni Aulino, Martina Petrucci, Silvia Valentini, Marcello Covino
Summary: This study aims to analyze the rate, clinical, and demographic features of electric scooter accidents reported to the Emergency Department of a university hospital in Rome. The findings show that fractures are the most common injury in electric scooter accidents, and helmet use is low.
FORENSIC SCIENCE MEDICINE AND PATHOLOGY
(2023)
Article
Medicine, General & Internal
Giuseppe De Matteis, Maria Livia Burzo, Davide Antonio Della Polla, Amato Serra, Andrea Russo, Francesco Landi, Antonio Gasbarrini, Giovanni Gambassi, Francesco Franceschi, Marcello Covino
Summary: Dementia is associated with higher rates of admission and mortality in hospitals. This retrospective study aimed to investigate the impact of dementia on in-hospital mortality and identify the predictors of mortality in these patients. The study compared the clinical outcomes of dementia patients and non-dementia patients at admission to the Emergency Department.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Critical Care Medicine
Marcello Covino, Claudio Sandroni, Davide Della Polla, Giuseppe De Matteis, Andrea Piccioni, Antonio De Vita, Andrea Russo, Sara Salini, Luigi Carbone, Martina Petrucci, Mariano Pennisi, Antonio Gasbarrini, Francesco Franceschi
Summary: The study aimed to compare the ability of different Early Warning Scores (EWS) to predict poor outcomes in adult patients in the emergency department. The results showed that NEWS was the most accurate predictor, followed by NEWS2. Neural network analysis highlighted the need for improvements in sepsis diagnosis and the measurement of respiratory rate.
Article
Infectious Diseases
Andrea Russo, Sara Salini, Giordana Gava, Giuseppe Merra, Andrea Piccioni, Giuseppe De Matteis, Gianluca Tullo, Angela Novelli, Martina Petrucci, Antonio Gasbarrini, Francesco Landi, Francesco Franceschi, Marcello Covino
Summary: This study evaluates the prognostic role of serum PCT in older patients with suspect sepsis or infective diagnosis in the Emergency Department, with a focus on frailty status. The results show that PCT values at ED admission do not predict infective diagnosis or higher odds of in-hospital death. However, in frail older adults, PCT values in ED can be a useful predictor of bloodstream infection.
Review
Biochemistry & Molecular Biology
Sara Cicchinelli, Federico Rosa, Federica Manca, Christian Zanza, Veronica Ojetti, Marcello Covino, Marcello Candelli, Antonio Gasbarrini, Francesco Franceschi, Andrea Piccioni
Summary: Cigarette smoke is a classic risk factor for many diseases, and dysbiosis of the microbiota has been identified as a new risk factor for several illnesses. There is evidence of a cross-interaction between cigarette smoke and dysbiosis, which may explain the pathogenesis of some diseases.
Review
Biochemistry & Molecular Biology
Andrea Piccioni, Federico Rosa, Sergio Mannucci, Federica Manca, Giuseppe Merra, Sabrina Chiloiro, Marcello Candelli, Marcello Covino, Antonio Gasbarrini, Francesco Franceschi
Summary: This article focuses on the relationship between alterations in the gut microbiome and the onset of type 1 diabetes mellitus and LADA, based on the latest evidence. It discusses the crucial role of the gut microbiota in the pathogenesis of these disorders and explores how modulating the gut microbiota through probiotics, prebiotics, and fecal microbiota transplantation can lead to potential therapeutic strategies.
Article
Pediatrics
Antonio Gatto, Eloisa Tiberi, Serena Ferretti, Valerio Santoro, Alessandra Piersanti, Filomena Valentina Paradiso, Lorenzo Nanni, Roberto Iezzi, Alessandro Posa, Simonetta Costa, Giovanni Vento
Summary: Acute kidney injury is a frequent complication in critical newborns, especially in extremely low-birth-weight infants. Peritoneal dialysis is currently the most manageable treatment, but there is a lack of data regarding the timing of irreversible diuresis relative to the start of PD.
Editorial Material
Gastroenterology & Hepatology
Fausto Rosa, Marcello Covino, Carlo Alberto Schena, Giuseppe Quero, Francesco Franceschi, Gabriele Sganga, Sergio Alfieri
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Geriatrics & Gerontology
Massimo Montalto, Antonella Gallo, Maria Chiara Agnitelli, Simona Pellegrino, Alice Lipari, Erika Pero, Marcello Covino, Francesco Landi, Antonio Gasbarrini, Giovanni Cammarota, Gianluca Ianiro
Summary: Fecal microbiota transplantation (FMT) is effective and safe for very old patients with recurrent Clostridioides difficile infection (rCDI). Frailty and high comorbidity do not limit the use of FMT in these patients. Frailty assessment has the potential to better identify patients at higher risk for worse outcomes or repeat treatment with FMT.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Gastroenterology & Hepatology
Giuseppe Marrone, Marcello Covino, Giuseppe Merra, Andrea Piccioni, Annamaria Amodeo, Angela Novelli, Rita Murri, Maurizio Pompili, Antonio Gasbarrini, Francesco Franceschi
Summary: This retrospective study evaluated the clinical course and outcome of COVID-19 patients treated with UDCA and found that UDCA treatment does not have a significant effect on the outcome of COVID-19. Further prospective studies are needed to evaluate its efficacy in preventing infection and severe disease.
LIVER INTERNATIONAL
(2023)
Article
Health Care Sciences & Services
Antonella Gallo, Marcello Covino, Alice Lipari, Simona Pellegrino, Francesca Ibba, Maria Chiara Agnitelli, Matteo Tosato, Francesco Landi, Massimo Montalto
Summary: This retrospective analysis examines the long-term impact of COVID-19 disease and finds that patients infected with COVID-19 require more chronic medication treatment. Disease severity and age are identified as the best predictors for an increase in medication usage, while anti-SARS-CoV-2 vaccination provides significant protection. Multidisciplinary and integrated care pathways should be implemented for older, frail patients and those with severe disease.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Pharmacology & Pharmacy
M. T. Congedo, M. Chiappetta, D. Nachira, F. Lococo, G. Calabrese, D. Tabacco, C. Sassorossi, A. Nocera, M. Covino, L. Petracca-ciavarella, M. L. Vita, V. Porziella, K. Kuzmych, S. Margaritora, E. Meacci
Summary: This study compared two positioning techniques for 12-French (Fr) thoracic drains in terms of efficacy, safety, and patient comfort. The results showed comparable pain and complication rates for both techniques, with efficient drainage of pleural effusion. It is recommended to use a longer tube for patients who require chest drainage for an extended period of time.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Review
Microbiology
Andrea Piccioni, Marcello Covino, Marcello Candelli, Veronica Ojetti, Annunziata Capacci, Antonio Gasbarrini, Francesco Franceschi, Giuseppe Merra
Summary: The human gastrointestinal tract harbors a complex and dynamic population of commensal bacteria that have evolved in symbiosis with the host. Diet plays a fundamental role in influencing the gut microbiota and understanding its beneficial effects on host metabolism. There is potential for probiotics to have a wider range of effects beyond influencing the colonizing microbiota, leading to innovation in the field. Food components can impact the composition of the intestinal microbiota, highlighting the importance of adopting a healthy lifestyle.
MICROBIOLOGY RESEARCH
(2023)
Article
Emergency Medicine
Marcello Candelli, Giulia Pignataro, Marta Sacco Fernandez, Sara Cicchinelli, Antonio Gulli, Enrico Torelli, Maurizio Gabrielli, Andrea Piccioni, Marcello Covino, Veronica Ojetti, Massimo Antonelli, Antonio Gasbarrini, Francesco Franceschi
Summary: This study aims to evaluate clinical and laboratory indicators associated with mortality and determine a prognostic score based on these variables. A score called ANCOC (Age, blood urea Nitrogen, C-reactive protein, Oxygen saturation, Comorbidities) was created to predict the risk of death in COVID-19 patients. The ANCOC score showed high diagnostic accuracy in predicting mortality.
