Palladium-Catalyzed Enantioselective 7-exo-Trig Carbopalladation/Carbonylation: Cascade Reactions To Achieve Atropisomeric Dibenzo[b,d]azepin-6-ones

Palladium‐Catalyzed Enantioselective Heck Carbonylation with a Monodentate Phosphoramidite Ligand: Asymmetric Synthesis of (+)‐Physostigmine, (+)‐Physovenine, and (+)‐Folicanthine

(2020) Ming Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Constructing chiral bicyclo[3.2.1]octanes via palladium-catalyzed asymmetric tandem Heck/carbonylation desymmetrization of cyclopentenes

(2020) Zhenbo Yuan et al.   Nature Communications

Discovery of novel, potent, and orally bioavailable pyrido[2,3-d][1]benzazepin-6-one antagonists for parathyroid hormone receptor 1

(2020) Yoshikazu Arai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Asymmetric Reductive Amination/Ring-Closing Cascade: Direct Synthesis of Enantioenriched Biaryl-Bridged NH Lactams

(2020) Yao Zhang et al.   ORGANIC LETTERS

Synthesis of Aminated Phenanthridinones via Palladium/Norbornene Catalysis

(2020) Xavier Abel-Snape et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Site-Selective C–H Bond Activation/Annulation Cascade toward Dibenzoazepinone Skeletons

(2020) Deepan Chowdhury et al.   ORGANIC LETTERS

Enantioselective Synthesis of 2-Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cylization Sequences: Method Development and Applications

(2019) Huaanzi Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Bridged Biaryl Atropisomers via Sequential Cu- and Pd-Catalyzed Asymmetric Ring Opening and Cyclization

(2019) Xiaoping Xue et al.   ORGANIC LETTERS

Asymmetric Hydrogenation of Dibenzo[c,e]azepine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts

(2019) Shanshan Zhang et al.   ORGANIC LETTERS

A 16-step synthesis of the isoryanodane diterpene (+)-perseanol

(2019) Arthur Han et al.   NATURE

Synthesis of Seven-Membered Azepino[3,2,1-hi]indoles via Rhodium-Catalyzed Regioselective C–H Activation/1,8-Diazabicyclo[5.4.0]undec-7-ene-Catalyzed Intramolecular Amidation of 7-Phenylindoles in One Pot

(2019) Yumeng Yuan et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions

(2018) Yuanyuan Ping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Axially Chiral Dibenzazepinones via a Pd(0)-Catalyzed Atropo-enantioselective C-H Arylation

(2018) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N,N-Chiral Ligands Enabling Palladium-catalyzed Enantioselective Intramolecular Heck-Matsuda Carbonylation Reactions by Sequential Migratory and CO Insertions

(2018) Carlos Roque Duarte Correia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Tautomerization of Metastable Enamines

(2017) Jingjing Liu et al.   ORGANIC LETTERS

Accessing Axially Chiral Biaryls via Organocatalytic Enantioselective Dynamic-Kinetic Resolution-Semipinacol Rearrangement

(2017) Yi Liu et al.   ACS Catalysis

Total Synthesis of (−)-Spinosyn A via Carbonylative Macrolactonization

(2016) Yu Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cascade C–H Functionalization/Amidation Reaction for Synthesis of Azepinone Derivatives

(2016) Peng Bai et al.   ORGANIC LETTERS

Pd-catalyzed Heck cyclization and in situ hydrocarboxylation or hydromethenylation via a hydrogen borrowing strategy

(2015) Xianglei Liu et al.   Organic Chemistry Frontiers

Enantioselective CH Arylation Strategy for Functionalized Dibenzazepinones with Quaternary Stereocenters

(2013) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bimetallic (Cu/Pd) catalytic cascade reactions to 3,3-disubstituted oxindole analogues

(2013) Gemma Packer et al.   RSC Advances

Domino Carbopalladation-Carbonylation: Investigation of Substrate Scope

(2012) Brinton Seashore-Ludlow et al.   ADVANCED SYNTHESIS & CATALYSIS

The asymmetric Heck and related reactions

(2011) Dennis Mc Cartney et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Dibenzazepinones by Palladium-Catalyzed Intramolecular Arylation ofo-(2′-Bromophenyl)anilide Enolates

(2010) Xiaohong Pan et al.   JOURNAL OF ORGANIC CHEMISTRY

Atropisomeric Properties of 7-, 8-, and 9-Membered-Ring Dibenzolactams: Conformation, Thermal Stability, and Chemical Reactivity

(2010) Hidetsugu Tabata et al.   JOURNAL OF ORGANIC CHEMISTRY

Domino Carbopalladation−Carbonylation: Generating Quaternary Stereocenters while Controlling β-Hydride Elimination

(2010) Brinton Seashore-Ludlow et al.   ORGANIC LETTERS

Atropisomeric Properties of the Dibenzo[b,d]azepin-6-one Nucleus

(2008) Hidetsugu Tabata et al.   ORGANIC LETTERS

Exploratory studies toward a total synthesis of the marine ascidian metabolite perophoramidine

(2008) Michael A. Evans et al.   TETRAHEDRON