Article
Dermatology
Wendy Smith Begolka, Raj Chovatiya, Isabelle J. Thibau, Jonathan Silverberg
Summary: The study investigated the out-of-pocket healthcare expenses associated with AD management among National Eczema Association members globally. It found that the expenses mainly included healthcare providers, nonprescription healthcare products, and complementary approaches, with the median annual AD OOP expense being $600.
Article
Urology & Nephrology
Daniel D. Joyce, Vidit Sharma, David H. Jiang, Holly K. Van Houten, Lindsey R. Sangaralingham, Bijan J. Borah, Eugene D. Kwon, David F. Penson, Stacie B. Dusetzina, Jon C. Tilburt, Stephen A. Boorjian
Summary: This study evaluated the patient-level factors associated with out-of-pocket costs for advanced prostate cancer treatment options. The findings showed that patients receiving novel hormonal therapy had significantly higher treatment-related out-of-pocket costs. Older age, Black race, lower comorbidity scores, and lower household income were associated with higher treatment-related out-of-pocket costs.
JOURNAL OF UROLOGY
(2022)
Article
Oncology
Jose A. Carreno Duenas, P. Natalia Sanchez, Carlos E. Bonilla
Summary: This study aimed to compare overall survival, progression-free survival, and treatment response between patients who participated in cancer clinical trials and those who refused to participate. The results showed that participants had higher rates of stable disease and complete response, and longer progression-free survival. Therefore, participation in clinical trials could improve treatment outcomes and reduce disease progression.
Article
Medicine, General & Internal
Mayanka Ambade, Rakesh Sarwal, Nachiket Mor, Rockli Kim, S. Subramanian
Summary: High out-of-pocket expenditure on health in India may hinder universal health coverage. This study analyzed the relative contribution of different components of health expenditure, revealing that nonmedical costs were significant and expenses on doctor consultations and diagnostic tests increased with socioeconomic status. Annual healthcare expenditure as a proportion of income was lower for inpatient services compared to outpatient services.
Review
Oncology
Nicolas Iragorri, Claire de Oliveira, Natalie Fitzgerald, Beverley Essue
Summary: The study found that cancer patients and their caregivers in the U.S. spent between USD 180 and USD 2600 per month, while in Canada it was USD 15-400, Western Europe USD 4-609, and Australia USD 58-438. Patients with breast or colorectal cancer spent around USD 200 per month, while pediatric cancer patients spent USD 800. Medical consultations and in-hospital care costs were estimated between USD 40-71 in high-income countries. In low- and middle-income countries and high-income countries, cancer patients and caregivers spent 42% and 16% of their annual income on out-of-pocket expenses, respectively.
Article
Multidisciplinary Sciences
Habib Hasan Farooqui, Anup Karan, Manu Raj Mathur, Suhaib Hussain, Sakthivel Selvaraj
Summary: This research examines out of pocket expenditure for the treatment of childhood infections in Indian households. The most common childhood infection is fever with rash, while viral hepatitis and tuberculosis have the highest treatment expenditure. The study also finds that the poorest households bear a disproportionately higher burden of out of pocket expenditure.
Article
Multidisciplinary Sciences
Nguyen Xuan Thanh, Robert Tanguay, Kiran J. Pohar Manhas, Ania X. Kania-Richmond, Sherri Kashuba, Tracey S. Geyer, John S. Pereira, Tracy S. Wasylak
Summary: This study estimated the economic burden of chronic pain in Alberta, Canada, and found that it imposes substantial healthcare and productivity costs. Interventions to improve chronic pain prevention and management are urgently needed.
Article
Oncology
Joanna Dodkins, Wilma M. Hopman, John Connor Wells, Yolande Lievens, R. A. Malik, C. S. Pramesh, Bishal Gyawali, Nazik Hammad, Deborah Mukherji, Richard Sullivan, Jeannette Parkes, Christopher M. Booth, Ajay Aggarwal
Summary: This study analyzes the landscape of radiation therapy randomized controlled trials (RCTs) and compares them with systemic therapy trials. The results indicate a need for greater investment in radiation therapy RCTs and highlight disparities in conducting RCTs globally. There is an urgent need for capacity building and sustainable funding sources in low-and-middle-income countries.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Article
Surgery
Feibi Zheng, Yongmei Huang, Jason Wright, Jennifer H. Kuo
Summary: This study aimed to determine out-of-pocket costs in commercially insured US patients undergoing thyroid surgery. The results showed that despite having commercial insurance, patients still face substantial out-of-pocket costs, with higher costs for malignant conditions.
Article
Multidisciplinary Sciences
Abdur Razzaque Sarker, S. M. Zulfiqar Ali, Maruf Ahmed, S. M. Zahedul Islam Chowdhury, Nausad Ali
Summary: This study investigates the self-reported illnesses and out-of-pocket healthcare expenditures among urban citizens in Dhaka, Bangladesh, and identifies the influence of socioeconomic, demographic, and behavioral factors on the expenditures.
Article
Oncology
Astrid J. Rodriguez-Acevedo, Raymond J. Chan, Catherine M. Olsen, Nirmala Pandeya, David C. Whiteman, Louisa G. Gordon
Summary: Out-of-pocket expenses for cancer patients have significantly increased over time, especially for women with breast cancer and those without private health insurance. These cost increases resulted from both higher prices and higher volumes of health services, with variations by cancer type.
Article
Obstetrics & Gynecology
Ashley R. Brant, Pelin Batur, Susana Arrigain, Rocio Lopez, Ruth M. Farrell
Summary: Between 2013 and 2016, 38% of women who had contraceptive prescriptions reported paying out-of-pocket, with an average annual expenditure of $216.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Kamil F. Faridi, Elias J. Dayoub, Joseph S. Ross, Sanket S. Dhruva, Tariq Ahmad, Nihar R. Desai
Summary: This study investigated the Medicare coverage and out-of-pocket costs of quadruple therapy for patients with heart failure. The findings showed that Medicare drug plans restrict coverage of quadruple therapy through cost sharing, making it unaffordable for many patients unless medication prices and cost sharing are reduced.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Kamil F. Faridi, Elias J. Dayoub, Joseph S. Ross, Sanket S. Dhruva, Tariq Ahmad, Nihar R. Desai
Summary: This study examines the Medicare coverage and out-of-pocket costs of quadruple therapy and regimens excluding ARNI or SGLT2i. The findings suggest that Medicare drug plans restrict the coverage of quadruple therapy through cost sharing, leading to substantially higher out-of-pocket costs compared to generic regimens.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Multidisciplinary Sciences
Kidu Gidey, Meles Tekie Gidey, Berhane Yohannes Hailu, Zigbey Brhane Gebreamlak, Yirga Legesse Niriayo
Summary: This study aims to assess the clinical and economic burden of Healthcare-associated infections (HAIs) in hospitalized patients in Ethiopia. The results show that HAIs have a significant impact on in-hospital mortality, length of hospital stays, and medical costs. The implementation of infection control strategies is necessary to prevent HAIs and save healthcare expenditure.
Article
Oncology
Justin T. Moyers, Roberto Carmagnani Pestana, Jason Roszik, David S. Hong, Aung Naing, Siqing Fu, Sarina Piha-Paul, Timothy A. Yap, Daniel Karp, Jordi Rodon, Andy Livingston, Maria Alejandra Zarzour, Vinod Ravi, Shreyaskumar Patel, Robert S. Benjamin, Joseph Ludwig, Cynthia Herzog, Ravin Ratan, Neeta Somaiah, Anthony Conley, Richard Gorlick, Funda Meric-Bernstam, Vivek Subbiah
Summary: In this study, the outcomes of patients with ultrarare sarcomas in Phase 1 trials were assessed. The results showed that the median overall survival of ultrarare sarcomas was similar to common sarcomas, but the objective response rate to treatment was higher. Genomic selection played a significant role in identifying molecular subsets likely to benefit from targeted therapy in Phase 1 trials.
CLINICAL CANCER RESEARCH
(2023)
Editorial Material
Oncology
Cathy J. Bradley, Ya-Chen Tina Shih, K. Robin Yabroff
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Meng Li, Kaiping Liao, Alice J. Chen, Tina Cascone, Yu Shen, Qian Lu, Ya-Chen Tina Shih
Summary: Nationwide, there is evidence to suggest that metastatic lung cancer patients residing in counties with a higher percentage of racialized population experience slower initiation of immune checkpoint inhibitor (ICI) therapy despite having a higher density of medical oncologists in their neighborhood.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Kathrin Milbury, Meagan Whisenant, Shiao-Pei Weathers, Smitha Malliaha, Stella Snyder, Natalie Jackson, Jing Li, Yisheng Li, Roseanglea F. Silva, Ya-Chen Tina Shih, Lorenzo Cohen
Summary: This study compared the effectiveness of dyadic yoga and individual caregiver yoga as supportive care strategies for family caregivers. The results showed that individual caregiver yoga had a greater subjective benefit for caregivers and led to improved mental quality of life and reduced financial burden. This study highlights the importance of individualized support for vulnerable caregiver populations.
Article
Oncology
Sarina A. Piha-Paul, Chieh Tseng, Hai T. Tran, Meng Gao, Daniel D. Karp, Vivek Subbiah, Apostolia Maria Tsimberidou, Jitesh D. Kawedia, Siqing Fu, Shubham Pant, Timothy A. Yap, Van K. Morris, Bryan K. Kee, Mariela Blum Murphy, JoAnn Lim, Funda Meric-Bernstam
Summary: The study aimed to evaluate the feasibility and safety of neratinib and trametinib combination therapy in patients with specific mutations/amplifications. The results showed that this combination therapy was toxic and had limited clinical efficacy, possibly due to suboptimal drug dosing caused by drug-drug interactions.
CANCER CHEMOTHERAPY AND PHARMACOLOGY
(2023)
Article
Oncology
Jason J. Luke, Sarina A. Piha-Paul, Theresa Medina, Claire F. Verschraegen, Mary Varterasian, Aoife M. Brennan, Richard J. Riese, Anna Sokolovska, James Strauss, David L. Hava, Filip Janku
CLINICAL CANCER RESEARCH
(2023)
Article
Oncology
Vishal R. Patel, Thomas B. Cwalina, Arjun Gupta, Nico Nortje, Samyukta Mullangi, Ravi B. Parikh, Ya-Chen Tina Shih, S. M. Qasim Hussaini
Summary: In this cross-sectional study, oncologist participation and performance in the 2019 MIPS were examined. Oncologist participation rate was found to be low (86%), compared to the overall participation rate (97%). It was also observed that oncologists using alternative payment models (APMs) as their filing source had higher MIPS scores, indicating the importance of organizational resources for participants.
Article
Oncology
Vishal R. Patel, Thomas B. Cwalina, Nico Nortje, Samyukta Mullangi, Ravi B. Parikh, Ya-Chen Tina Shih, Arjun Gupta, S. M. Qasim Hussaini
Summary: The Merit-Based Incentive Payment System (MIPS) is the only federally mandated value-based payment model for oncologists. The inclusion of cost measures in MIPS may disproportionately affect oncologists, who have higher costs of care compared to other specialties. This study examines the implications of incorporating cost measures on physician reimbursements and highlights the need for specialty-specific recalibration to ensure fairness and preserve healthcare quality.
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
I-Wen Pan, Tina W. F. Yen, Isabelle Bedrosian, Ya-Chen Tina Shih
Summary: This study examines the trends and associated factors of preoperative breast MRI use among early-stage breast cancer patients. The results show that the use of preoperative breast MRI has steadily increased. In addition to clinical factors, age, race/ethnicity, and geographic location are associated with the use of preoperative MRI.
JCO ONCOLOGY PRACTICE
(2023)
Article
Health Care Sciences & Services
Thanh Cong Bui, Charles E. Hoogland, Chhorvann Chhea, Heng Sopheab, Vichea Ouk, Sovannarith Samreth, Bunleng Hor, Jennife Vidrine, Michael S. Businelle, Ya Chen Tina Shih, Steven K. Sutton, Sarah R. Jones, Bethany Shorey Fennell, Cherell Cottrell-Daniels, Summer G. Frank-Pearce, Chamnab Ngor, Shweta Kulkarni, Damon J. Vidrine
Summary: This paper describes the design, methods, and data analysis plans for a randomized controlled trial assessing the efficacy of a theory-based mobile health smoking cessation intervention in Cambodian people with HIV. By comparing the efficacy of a mobile health-based automated messaging intervention versus standard care, this study has the potential to transform HIV care in Cambodia and prevent tobacco-related diseases.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Oncology
Andrew M. D. Wolf, Kevin C. Oeffinger, Tina Ya-Chen Shih, Louise C. Walter, Timothy R. Church, Elizabeth T. H. Fontham, Elena B. Elkin, Ruth D. Etzioni, Carmen E. Guerra, Rebecca B. Perkins, Karli K. Kondo, Tyler B. Kratzer, Deana Manassaram-Baptiste, William L. Dahut, Robert A. Smith
Summary: Lung cancer is the leading cause of cancer-related deaths and years of life lost in the US. Early detection through screening has been shown to reduce mortality. The American Cancer Society has updated its guidelines for lung cancer screening, recommending annual low-dose CT screening for individuals aged 50-80 who currently smoke or formerly smoked and have a significant smoking history.
CA-A CANCER JOURNAL FOR CLINICIANS
(2023)
Article
Oncology
Tina W. F. Yen, I-Wen Pan, Ya-Chen Tina Shih
Summary: During the COVID-19 pandemic, telehealth use among patients diagnosed with cancer increased, particularly in states with more lenient policies. This study emphasizes the importance of considering telehealth policies that can benefit vulnerable patient populations.
JNCI CANCER SPECTRUM
(2023)
Article
Mathematical & Computational Biology
Shikun Wang, Yu Shen, Ya-Chen Tina Shih, Ying Xu, Liang Li
Summary: Estimating the cost of cancer care is crucial for policymakers. This study proposes a semiparametric approach to estimate the longitudinal cost trajectories of cancer patients by considering survival and longitudinal medical cost data. The proposed method balances model flexibility, statistical efficiency, and computational tractability. The method was used to estimate the cost trajectories of renal cell cancer patients using a linked database.
Review
Biotechnology & Applied Microbiology
Apostolia M. Tsimberidou, Mehmet A. Baysal, Abhijit Chakraborty, Borje S. Andersson
Summary: This study developed a personalized autologous T-cell therapy program for advanced cancer patients. The treatment showed promising results with a high rate of disease stabilization and prolonged disease control in some patients. The feasibility and tolerability of IMA101 were demonstrated, highlighting the potential of multi-targeted adoptive cell therapy for further investigation.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2023)
Article
Multidisciplinary Sciences
Elena Fountzilas, Henry Hiep Vo, Peter Mueller, Razelle Kurzrock, Apostolia-Maria Tsimberidou
Summary: A literature search was conducted in PubMed to identify phase I/II clinical trials with FDA-approved immunotherapy drugs from 2018 to 2020, and relevant data were compiled for analysis.