Co-released norepinephrine and galanin act on different timescales to promote stress-induced anxiety-like behavior

Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors

(2020) Rachel P. Tillage et al.   Brain Structure & Function

Central norepinephrine transmission is required for stress-induced repetitive behavior in two rodent models of obsessive-compulsive disorder

(2020) Daniel Lustberg et al.   PSYCHOPHARMACOLOGY

Chronic Environmental or Genetic Elevation of Galanin in Noradrenergic Neurons Confers Stress Resilience in Mice

(2020) Rachel P. Tillage et al.   JOURNAL OF NEUROSCIENCE

Noradrenergic circuits in the forebrain control affective responses to novelty

(2020) Daniel Lustberg et al.   PSYCHOPHARMACOLOGY

Chemogenetic silencing of the Locus Coeruleus-Basolateral Amygdala pathway abolishes pain-induced anxiety and enhanced aversive learning in rats

(2019) Meritxell Llorca-Torralba et al.   BIOLOGICAL PSYCHIATRY

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning

(2019) Matthew B. Pomrenze et al.   Cell Reports

Locus Coeruleus Norepinephrine Drives Stress-Induced Increases in Basolateral Amygdala Firing and Impairs Extinction Learning

(2019) Thomas F. Giustino et al.   JOURNAL OF NEUROSCIENCE

Persistent Stress-Induced Neuroplastic Changes in the Locus Coeruleus/Norepinephrine System

(2018) Olga Borodovitsyna et al.   NEURAL PLASTICITY

What Acute Stress Protocols Can Tell Us About PTSD and Stress-Related Neuropsychiatric Disorders

(2018) Laura Musazzi et al.   Frontiers in Pharmacology

Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness

(2018) Tomas Hökfelt et al.   Frontiers in Neural Circuits

β-Adrenoceptor Blockade in the Basolateral Amygdala, But Not the Medial Prefrontal Cortex, Rescues the Immediate Extinction Deficit

(2017) Thomas F Giustino et al.   NEUROPSYCHOPHARMACOLOGY

Ascending mechanisms of stress integration: Implications for brainstem regulation of neuroendocrine and behavioral stress responses

(2017) Brent Myers et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

(2017) Jordan G McCall et al.   eLife

Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin

(2016) David Weinshenker et al.   BRAIN RESEARCH

CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety

(2015) Jordan G. McCall et al.   NEURON

Galanin mediates features of neural and behavioral stress resilience afforded by exercise

(2015) N.R. Sciolino et al.   NEUROPHARMACOLOGY

Positive allosteric modulators to peptide GPCRs: a promising class of drugs

(2013) Tamas Bartfai et al.   ACTA PHARMACOLOGICA SINICA

Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe

(2013) E. Le Maitre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise offers anxiolytic potential: A role for stress and brain noradrenergic-galaninergic mechanisms

(2012) Natale R. Sciolino et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic Inhibition of Dopamine β-Hydroxylase Facilitates Behavioral Responses to Cocaine in Mice

(2012) Meriem Gaval-Cruz et al.   PLoS One

Galanin Receptors and Ligands

(2012) Kristin E. B. Webling et al.   Frontiers in Endocrinology

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Norepinephrine Signaling Through β-Adrenergic Receptors is Critical for Expression of Cocaine-Induced Anxiety

(2008) Jesse R. Schank et al.   BIOLOGICAL PSYCHIATRY

Convergent regulation of locus coeruleus activity as an adaptive response to stress

(2008) Rita J. Valentino et al.   EUROPEAN JOURNAL OF PHARMACOLOGY