标题
An atlas of mitochondrial DNA genotype–phenotype associations in the UK Biobank
作者
关键词
-
出版物
NATURE GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-05-18
DOI
10.1038/s41588-021-00868-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genetics of 35 blood and urine biomarkers in the UK Biobank
- (2021) Nasa Sinnott-Armstrong et al. NATURE GENETICS
- Mitochondrial TCA cycle metabolites control physiology and disease
- (2020) Inmaculada Martínez-Reyes et al. Nature Communications
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
- (2020) Praveen Surendran et al. NATURE GENETICS
- Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases
- (2019) Tatjana Holzer et al. JOURNAL OF CELL BIOLOGY
- Germline selection shapes human mitochondrial DNA diversity
- (2019) Wei Wei et al. SCIENCE
- Role of Mitochondria in the Mechanism(s) of Action of Metformin
- (2019) Guillaume Vial et al. Frontiers in Endocrinology
- Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm
- (2019) Miquel Navas-Madroñal et al. CLINICAL SCIENCE
- Mitocellular communication: Shaping health and disease
- (2019) Adrienne Mottis et al. SCIENCE
- Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy
- (2019) Ana Latorre-Pellicer et al. Cell Metabolism
- mtDNA Haplogroup N9a Increases the Risk of Type 2 Diabetes by Altering Mitochondrial Function and Intracellular Mitochondrial Signals
- (2018) Hezhi Fang et al. DIABETES
- Mitochondrial Toxicity
- (2018) Joel N Meyer et al. TOXICOLOGICAL SCIENCES
- Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry
- (2018) Loic Yengo et al. HUMAN MOLECULAR GENETICS
- Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits
- (2018) Aldi T. Kraja et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Height as a clinical biomarker of disease burden in adult mitochondrial disease
- (2018) Rachel L Boal et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- HmtVar: a new resource for human mitochondrial variations and pathogenicity data
- (2018) Roberto Preste et al. NUCLEIC ACIDS RESEARCH
- Oldies but Goldies mtDNA Population Variants and Neurodegenerative Diseases
- (2018) Patrick F. Chinnery et al. Frontiers in Neuroscience
- Inherited eye-related disorders due to mitochondrial dysfunction
- (2017) Patrick Yu-Wai-Man et al. HUMAN MOLECULAR GENETICS
- The hallmarks of mitochondrial dysfunction in chronic kidney disease
- (2017) Daniel L. Galvan et al. KIDNEY INTERNATIONAL
- Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila
- (2017) Tiina S. Salminen et al. MITOCHONDRION
- Mitochondrial energetics in the kidney
- (2017) Pallavi Bhargava et al. Nature Reviews Nephrology
- Mutations in mitochondrial DNA causing tubulointerstitial kidney disease
- (2017) Thomas M. Connor et al. PLoS Genetics
- Association Between Mitochondrial DNA Haplogroup Variation and Autism Spectrum Disorders
- (2017) Dimitra Chalkia et al. JAMA Psychiatry
- Mitochondrial DNA haplogroups influence the risk of incident knee osteoarthritis in OAI and CHECK cohorts. A meta-analysis and functional study
- (2016) Mercedes Fernández-Moreno et al. ANNALS OF THE RHEUMATIC DISEASES
- RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data: Table 1.
- (2016) Xiaowei Zhan et al. BIOINFORMATICS
- FINEMAP: efficient variable selection using summary data from genome-wide association studies
- (2016) Christian Benner et al. BIOINFORMATICS
- The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
- (2016) William J. Astle et al. CELL
- Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing
- (2016) Ana Latorre-Pellicer et al. NATURE
- HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing
- (2016) Hansi Weissensteiner et al. NUCLEIC ACIDS RESEARCH
- Mitochondrial DNA mutations in neurodegeneration
- (2015) Michael J. Keogh et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The fine-scale genetic structure of the British population
- (2015) Stephen Leslie et al. NATURE
- The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease
- (2015) James B. Stewart et al. NATURE REVIEWS GENETICS
- Mitochondrial DNA sequence variation in multiple sclerosis
- (2015) Gregory J. Tranah et al. NEUROLOGY
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
- (2015) Louise V Wain et al. Lancet Respiratory Medicine
- MToolBox: a highly automated pipeline for heteroplasmy annotation and prioritization analysis of human mitochondrial variants in high-throughput sequencing
- (2014) Claudia Calabrese et al. BIOINFORMATICS
- RAREMETAL: fast and powerful meta-analysis for rare variants
- (2014) S. Feng et al. BIOINFORMATICS
- Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming
- (2014) M. Picard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recent Mitochondrial DNA Mutations Increase the Risk of Developing Common Late-Onset Human Diseases
- (2014) Gavin Hudson et al. PLoS Genetics
- Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies
- (2014) Sabrina L Mitchell et al. BioData Mining
- Recommended Joint and Meta-Analysis Strategies for Case-Control Association Testing of Single Low-Count Variants
- (2013) Clement Ma et al. GENETIC EPIDEMIOLOGY
- Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease
- (2013) G. Hudson et al. NEUROLOGY
- ClinVar: public archive of relationships among sequence variation and human phenotype
- (2013) Melissa J. Landrum et al. NUCLEIC ACIDS RESEARCH
- Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease
- (2013) D. C. Wallace et al. Cold Spring Harbor Perspectives in Biology
- Oxidative phosphorylation differences between mitochondrial DNA haplogroups modify the risk of Leber's hereditary optic neuropathy
- (2012) Aurora Gómez-Durán et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- SIRT3 gene expression: A link between inherited mitochondrial DNA variants and oxidative stress
- (2012) Patrizia D'Aquila et al. GENE
- Mitochondrial antibiograms in personalized medicine
- (2012) D. Pacheu-Grau et al. HUMAN MOLECULAR GENETICS
- Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster
- (2012) C.C. Correa et al. MITOCHONDRION
- Decreased Reactive Oxygen Species Production in Cells with Mitochondrial Haplogroups Associated with Longevity
- (2012) Ai Chen et al. PLoS One
- Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans
- (2012) F. Ji et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Global DNA methylation levels are modulated by mitochondrial DNA variants
- (2012) Dina Bellizzi et al. Epigenomics
- Mitochondrial DNA Backgrounds Might Modulate Diabetes Complications Rather than T2DM as a Whole
- (2011) Alessandro Achilli et al. PLoS One
- Quality control and quality assurance in genotypic data for genome-wide association studies
- (2010) Cathy C. Laurie et al. GENETIC EPIDEMIOLOGY
- Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups
- (2010) Aurora Gómez-Durán et al. HUMAN MOLECULAR GENETICS
- A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
- (2010) Sander Michel Houten et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication
- (2009) Sarit Suissa et al. PLoS Genetics
- Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
- (2008) Hannah R. Elliott et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
- (2008) Mannis van Oven et al. HUMAN MUTATION
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