A genome-wide atlas of co-essential modules assigns function to uncharacterized genes
出版年份 2021 全文链接
标题
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes
作者
关键词
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出版物
NATURE GENETICS
Volume 53, Issue 5, Pages 638-649
出版商
Springer Science and Business Media LLC
发表日期
2021-04-16
DOI
10.1038/s41588-021-00840-z
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A reference map of the human binary protein interactome
- (2020) Katja Luck et al. NATURE
- TheTMEM189gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens
- (2020) Ernst R. Werner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cauchy combination test: a powerful test with analytic p-value calculation under arbitrary dependency structures
- (2019) Yaowu Liu et al. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
- The fusion landscape of hepatocellular carcinoma
- (2019) Chengpei Zhu et al. Molecular Oncology
- ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies
- (2019) Yaowu Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- WRN helicase is a synthetic lethal target in microsatellite unstable cancers
- (2019) Edmond M. Chan et al. NATURE
- A longitudinal big data approach for precision health
- (2019) Sophia Miryam Schüssler-Fiorenza Rose et al. NATURE MEDICINE
- CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
- (2019) Christopher J. Shoemaker et al. PLOS BIOLOGY
- Benchmark and integration of resources for the estimation of human transcription factor activities
- (2019) Luz Garcia-Alonso et al. GENOME RESEARCH
- Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia
- (2019) Frédéric M Vaz et al. BRAIN
- A bacterial light response reveals an orphan desaturase for human plasmalogen synthesis
- (2019) Aránzazu Gallego-García et al. SCIENCE
- Mapping the Genetic Landscape of Human Cells
- (2018) Max A. Horlbeck et al. CELL
- EPT1 (selenoprotein I) is critical for the neural development and maintenance of plasmalogen in humans
- (2018) Yasuhiro Horibata et al. JOURNAL OF LIPID RESEARCH
- Toward an integrated map of genetic interactions in cancer cells
- (2018) Benedikt Rauscher et al. Molecular Systems Biology
- Dual gene activation and knockout screen reveals directional dependencies in genetic networks
- (2018) Michael Boettcher et al. NATURE BIOTECHNOLOGY
- A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
- (2018) David K. Breslow et al. NATURE GENETICS
- The Expanding World of N-MYC–Driven Tumors
- (2018) David S. Rickman et al. Cancer Discovery
- Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens
- (2018) Joshua Pan et al. Cell Systems
- Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
- (2018) Eric Shifrut et al. CELL
- High‐resolution mapping of cancer cell networks using co‐functional interactions
- (2018) Evan A Boyle et al. Molecular Systems Biology
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma
- (2018) Kévin Contrepois et al. Scientific Reports
- Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes
- (2017) Kevin Drew et al. Molecular Systems Biology
- Architecture of the human interactome defines protein communities and disease networks
- (2017) Edward L. Huttlin et al. NATURE
- Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
- (2017) Kyuho Han et al. NATURE BIOTECHNOLOGY
- Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
- (2017) Robin M Meyers et al. NATURE GENETICS
- Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
- (2017) John Paul Shen et al. NATURE METHODS
- Genetic interaction mapping in mammalian cells using CRISPR interference
- (2017) Dan Du et al. NATURE METHODS
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast
- (2016) François Collard et al. Nature Chemical Biology
- Expansion of the Gene Ontology knowledgebase and resources
- (2016) NUCLEIC ACIDS RESEARCH
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Multiomic Analysis of the UV-Induced DNA Damage Response
- (2016) Stefan Boeing et al. Cell Reports
- Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
- (2016) Joseph Rosenbluh et al. Cell Systems
- Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents
- (2015) Valentina Piano et al. ACS Chemical Biology
- Diffusion maps for high-dimensional single-cell analysis of differentiation data
- (2015) Laleh Haghverdi et al. BIOINFORMATICS
- The BioPlex Network: A Systematic Exploration of the Human Interactome
- (2015) Edward L. Huttlin et al. CELL
- High-throughput functional genomics using CRISPR–Cas9
- (2015) Ophir Shalem et al. NATURE REVIEWS GENETICS
- Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation
- (2015) Y-W Zhang et al. ONCOGENE
- NFATc2 is an intrinsic regulator of melanoma dedifferentiation
- (2015) V Perotti et al. ONCOGENE
- Gene essentiality and synthetic lethality in haploid human cells
- (2015) V. A. Blomen et al. SCIENCE
- PHLDA2 is a key oncogene-induced negative feedback inhibitor of EGFR/ErbB2 signaling via interference with AKT signaling
- (2015) Xiaoqi Wang et al. Oncotarget
- RNAi screening comes of age: improved techniques and complementary approaches
- (2014) Stephanie E. Mohr et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems
- (2014) Yasunobu Okamura et al. NUCLEIC ACIDS RESEARCH
- A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility
- (2013) Michael C. Bassik et al. CELL
- GENCODE: The reference human genome annotation for The ENCODE Project
- (2012) J. Harrow et al. GENOME RESEARCH
- Detecting overlapping protein complexes in protein-protein interaction networks
- (2012) Tamás Nepusz et al. NATURE METHODS
- Genomic inflation factors under polygenic inheritance
- (2011) Jian Yang et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A Decade of Systems Biology
- (2010) Han-Yu Chuang et al. Annual Review of Cell and Developmental Biology
- snRNA 3′ end formation: the dawn of the Integrator complex
- (2010) Jiandong Chen et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Sox proteins in melanocyte development and melanoma
- (2010) Melissa L. Harris et al. Pigment Cell & Melanoma Research
- The Genetic Landscape of a Cell
- (2010) M. Costanzo et al. SCIENCE
- FATTY ACID DESATURASE4 of Arabidopsis encodes a protein distinct from characterized fatty acid desaturases
- (2009) Jinpeng Gao et al. PLANT JOURNAL
- Feedback regulation of DUSP6 transcription responding to MAPK1 via ETS2 in human cells
- (2008) Toru Furukawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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