Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis
出版年份 2021 全文链接
标题
Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis
作者
关键词
-
出版物
Nature Chemistry
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-04-20
DOI
10.1038/s41557-021-00662-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Automated radial synthesis of organic molecules
- (2020) Sourav Chatterjee et al. NATURE
- Seven-Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification
- (2019) M. Grace Russell et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- An overview of late-stage functionalization in today’s drug discovery
- (2019) Michael Moir et al. Expert Opinion on Drug Discovery
- A robotic platform for flow synthesis of organic compounds informed by AI planning
- (2019) Connor W. Coley et al. SCIENCE
- Traceless Solid-Phase Organic Synthesis
- (2019) Naděžda Cankařová et al. CHEMICAL REVIEWS
- The Molecular Industrial Revolution: Automated Synthesis of Small Molecules
- (2018) Melanie Trobe et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Towards the generalized iterative synthesis of small molecules
- (2018) Jonathan W. Lehmann et al. Nature Reviews Chemistry
- Assessing the possibilities of designing a unified multistep continuous flow synthesis platform
- (2018) Mrityunjay K Sharma et al. Beilstein Journal of Organic Chemistry
- Reconfigurable system for automated optimization of diverse chemical reactions
- (2018) Anne-Catherine Bédard et al. SCIENCE
- Organic synthesis in a modular robotic system driven by a chemical programming language
- (2018) Sebastian Steiner et al. SCIENCE
- A fully automated flow-based approach for accelerated peptide synthesis
- (2017) Alexander J Mijalis et al. Nature Chemical Biology
- Automating drug discovery
- (2017) Gisbert Schneider NATURE REVIEWS DRUG DISCOVERY
- Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions
- (2017) Kevin P. Cole et al. SCIENCE
- The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
- (2016) Tim Cernak et al. CHEMICAL SOCIETY REVIEWS
- The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells
- (2016) Mark C. Bagley et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
- (2016) A. Adamo et al. SCIENCE
- Supported Catalysis in Continuous-Flow Microreactors
- (2015) Rajesh Munirathinam et al. ADVANCED SYNTHESIS & CATALYSIS
- Organic Synthesis: March of the Machines
- (2015) Steven V. Ley et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
- (2015) Bernhard Gutmann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multistep continuous-flow synthesis of (R)- and (S)-rolipram using heterogeneous catalysts
- (2015) Tetsu Tsubogo et al. NATURE
- Synthesis of many different types of organic small molecules using one automated process
- (2015) J. Li et al. SCIENCE
- A Three-Minute Synthesis and Purification of Ibuprofen: Pushing the Limits of Continuous-Flow Processing
- (2014) David R. Snead et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction
- (2014) Eric M. Woerly et al. Nature Chemistry
- Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin
- (2012) François Lévesque et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- On Being Green: Can Flow Chemistry Help?
- (2012) Steven V. Ley CHEMICAL RECORD
- Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis
- (2011) Ryan L. Hartman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A flow-based synthesis of Imatinib: the API of Gleevec
- (2010) Mark D. Hopkin et al. CHEMICAL COMMUNICATIONS
- Continuous flow based catch and release protocol for the synthesis of α-ketoesters
- (2009) Alessandro Palmieri et al. Beilstein Journal of Organic Chemistry
- Advances in Solution- and Solid-Phase Synthesis toward the Generation of Natural Product-like Libraries
- (2009) Jyoti P. Nandy et al. CHEMICAL REVIEWS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now