Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity

SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4

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Dissection of intercellular communication using the transcriptome-based framework ICELLNET

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Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

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Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

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Immunology of COVID-19: current state of the science

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Risk-adapted Treatment Strategy For COVID-19 Patients

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SARS-CoV-2: a storm is raging

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Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

(2020) Yonggang Zhou et al.   National Science Review

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

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Tocilizumab for treatment of mechanically ventilated patients with COVID-19

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Cytokine Storms: Understanding COVID-19

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Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients

(2020) Linnan Zhu et al.   IMMUNITY

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

(2020) Robert Lorenz Chua et al.   NATURE BIOTECHNOLOGY

Single-cell landscape of immunological responses in patients with COVID-19

(2020) Ji-Yuan Zhang et al.   NATURE IMMUNOLOGY

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

SARS‐CoV‐2 infection in a neutropenic pediatric patient with leukemia: Addressing the need for universal guidelines for treatment of SARS‐CoV‐2‐positive, immunocompromised patients

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Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

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Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells

(2020) Megan L. Stanifer et al.   Cell Reports

Endothelial cells orchestrate COVID-19 coagulopathy

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Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19

(2020) Jeong Seok Lee et al.   Science Immunology

The laboratory tests and host immunity of COVID-19 patients with different severity of illness

(2020) Feng Wang et al.   JCI Insight

Molecular Architecture of the SARS-CoV-2 Virus

(2020) Hangping Yao et al.   CELL

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

A dynamic COVID-19 immune signature includes associations with poor prognosis

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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

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SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

(2020) David Olagnier et al.   Nature Communications

The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing

(2020) Gang Xu et al.   Cell Discovery

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

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Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison

(2020) Ioanna-Evdokia Galani et al.   NATURE IMMUNOLOGY

Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19

(2020) Marthe Jøntvedt Jørgensen et al.   Scientific Reports

Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients

(2020) Changfu Yao et al.   Cell Reports

A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patients

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The single-cell transcriptional landscape of mammalian organogenesis

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A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication

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Fast, sensitive and accurate integration of single-cell data with Harmony

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Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion

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Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

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Human dendritic cell subsets: an update

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Dendritic cells as cancer therapeutics

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Association between mRNA expression of CD74 and IL10 and risk of ICU-acquired infections: a multicenter cohort study

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Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

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Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

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Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells

(2017) Javier Rodríguez-Ubreva et al.   Cell Reports

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells

(2017) James R. Bowen et al.   PLoS Pathogens

Sepsis-induced immune dysfunction: can immune therapies reduce mortality?

(2016) Matthew J. Delano et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation

(2016) Jun Xu et al.   JOURNAL OF IMMUNOLOGY

Functional characterization of somatic mutations in cancer using network-based inference of protein activity

(2016) Mariano J Alvarez et al.   NATURE GENETICS

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

The role of dendritic cells in immunity against primary herpes simplex virus infections

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DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

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Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

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Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

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DHX9 Pairs with IPS-1 To Sense Double-Stranded RNA in Myeloid Dendritic Cells

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DC subsets in positive and negative regulation of immunity

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