Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model

Maraviroc attenuates the pathogenesis of experimental autoimmune encephalitis

(2020) Sajad Karampoor et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Study of the adoptive immunotherapy on rheumatoid arthritis with Thymus-derived invariant natural killer T cells

(2019) Dongzhi Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The protective effects of the GPR39 agonist TC-G 1008 against TNF-α-induced inflammation in human fibroblast-like synoviocytes (FLSs)

(2019) Weixia Jing et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Retinoic Acid Receptor-Related Receptor Alpha Ameliorates Autoimmune Arthritis via Inhibiting of Th17 Cells and Osteoclastogenesis

(2019) Jin-Sil Park et al.   Frontiers in Immunology

CXCR3 antagonist AMG487 suppresses rheumatoid arthritis pathogenesis and progression by shifting the Th17/Treg cell balance

(2019) Saleh A. Bakheet et al.   CELLULAR SIGNALLING

Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials

(2017) Yaxiong Deng et al.   HUMAN IMMUNOLOGY

RANTES/CCL5 Induces Collagen Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

(2017) Solomon A. Agere et al.   Frontiers in Immunology

Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice

(2017) Mirza Muhammad Fahd Qadir et al.   INFLAMMOPHARMACOLOGY

IL-9, a local growth factor for synovial T cells in inflammatory arthritis

(2016) Smriti Kundu-Raychaudhuri et al.   CYTOKINE

CCR5 blockade combined with cyclosporine A attenuates liver GVHD by impairing T cells function

(2016) Bo Tang et al.   INFLAMMATION RESEARCH

The tyrosine kinase inhibitor tyrphostin AG126 reduces activation of inflammatory cells and increases Foxp3 + regulatory T cells during pathogenesis of rheumatoid arthritis

(2016) Sheikh Fayaz Ahmad et al.   MOLECULAR IMMUNOLOGY

Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis

(2016) Andrea Mencarelli et al.   Scientific Reports

Anti-Citrullinated Protein Antibodies Induce Macrophage Subset Disequilibrium in RA Patients

(2015) Wei Zhu et al.   INFLAMMATION

IRF4 Is a Critical Gene in Retinoic Acid–Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency–Derived B Cells

(2015) Randi L. Indrevær et al.   JOURNAL OF IMMUNOLOGY

Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis

(2015) F. Ciccia et al.   RHEUMATOLOGY

Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice

(2015) Yuya Kondo et al.   ARTHRITIS RESEARCH & THERAPY

Maraviroc: a review of its use in HIV infection and beyond

(2015) Georgette Kanmogne et al.   Drug Design Development and Therapy

Differential Effects of IL-17A and TNF-α on Osteoblastic Differentiation of Isolated Synoviocytes and on Bone Explants from Arthritis Patients

(2015) Bilal Osta et al.   Frontiers in Immunology

Tumour Necrosis Factor α Antagonists in the Treatment of Rheumatoid Arthritis: An Immunological Perspective

(2014) Pier-Luigi Meroni et al.   BIODRUGS

Involvement of histamine 4 receptor in the pathogenesis and progression of rheumatoid arthritis

(2014) Adel R. A. Abd-Allah et al.   INTERNATIONAL IMMUNOLOGY

Efficacy of the CCR5 Antagonist Maraviroc in Reducing Early, Ritonavir-Induced Atherogenesis and Advanced Plaque Progression in Mice

(2013) Sabrina Cipriani et al.   CIRCULATION

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

(2013) Q. Tan et al.   SCIENCE

Interleukin-21 Receptor Deficiency Increases the Initial Toll-like Receptor 2 Response but Protects Against Joint Pathology by Reducing Th1 and Th17 Cells During Streptococcal Cell Wall Arthritis

(2013) Renoud J. Marijnissen et al.   Arthritis & Rheumatology

Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis

(2012) SY Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

In vitro effects of the CCR5 inhibitor maraviroc on human T cell function

(2012) H. Arberas et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

(2012) Ran Reshef et al.   NEW ENGLAND JOURNAL OF MEDICINE

Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial

(2012) Dona L Fleishaker et al.   ARTHRITIS RESEARCH & THERAPY

Serum Interleukin 9 Levels Are Increased in Patients with Systemic Sclerosis: Association with Lower Frequency and Severity of Pulmonary Fibrosis

(2011) KOICHI YANABA et al.   JOURNAL OF RHEUMATOLOGY

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

(2010) Partha S. Biswas et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

(2010) A. J. Hueber et al.   JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis

(2009) Jan Piet van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

IL-9 as a mediator of Th17-driven inflammatory disease

(2009) Elizabeth C. Nowak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

(2009) A. Jager et al.   JOURNAL OF IMMUNOLOGY

The role of interleukin-17 in the pathogenesis of rheumatoid arthritis

(2009) Sarah L. Gaffen   Current Rheumatology Reports

Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production

(2008) Cherry Kam Chun Lo et al.   ARTHRITIS AND RHEUMATISM

Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients

(2008) Takuji Iwamoto et al.   FEBS Journal