期刊
EUROPEAN JOURNAL OF NEUROLOGY
卷 23, 期 4, 页码 744-750出版社
WILEY
DOI: 10.1111/ene.12932
关键词
Beck Depression Inventory II; Chicago Multiscale Depression Inventory; depression; multiple sclerosis
资金
- Biogen Idec
- Merck Serono
- Fondazione Italiana Sclerosi Multipla
- Genzyme
- Novartis
- Teva
Background and purposeDepression is the most common psychiatric disorder in multiple sclerosis (MS). Self-report depression scales are frequently used as screening, diagnostic and grading instruments. This study investigated the psychometric properties of the Beck Depression Inventory second edition (BDI-II) for assessing depressive disorders in a sample of Italian MS patients. MethodsThe sample included 141 consecutive non-demented MS patients who completed the BDI-II and the Chicago Multiscale Depression Inventory (CMDI). MS patients also completed a clinical interview, a neurological/neuropsychological examination and a Fatigue Severity Score (FSS) questionnaire in order to assess divergent validity. ResultsThe BDI-II showed good internal consistency (Cronbach's alpha 0.89) and good convergent and divergent validity. With respect to CMDI serving as the gold standard', the receiver operating characteristic curve revealed that BDI-II is an adequate diagnostic measure and that the optimum total cut-off score was 18.5. Such score identified clinically relevant depressive symptoms in 25.5% of our MS sample. ConclusionsThe BDI-II is a simple, reliable and valid tool for detecting and grading depressive symptoms in Italian MS patients.
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