Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review

Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis

(2019)   BMC Medicine

An alternative dogma on reduced artemisinin susceptibility: A new shadow from east to west

(2019) Thirumalaisamy P. Velavan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Velavan et al.: Polymorphisms ofpfcoroninin natural populations: Implications for functional significance

(2019) Aabha I. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa?

(2019) Francis Foguim Tsombeng et al.   MALARIA JOURNAL

Polymorphisms in the K13 Gene in Plasmodium falciparum from Different Malaria Transmission Areas of Kenya

(2018) Zaydah R. de Laurent et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Impacts of Antimalarial Drugs on Plasmodium falciparum Drug Resistance Markers, Western Kenya, 2003–2015

(2018) Elizabeth Hemming-Schroeder et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Prevalence of molecular markers of artemisinin and lumefantrine resistance among patients with uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2015

(2018) Dragan Ljolje et al.   MALARIA JOURNAL

Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolates

(2018) Jing Wang et al.   MALARIA JOURNAL

High prevalence of Plasmodium falciparum antimalarial drug resistance markers in isolates from asymptomatic patients from the Republic of the Congo between 2010 and 2015

(2018) Dominique Fatima Voumbo-Matoumona et al.   Journal of Global Antimicrobial Resistance

Molecular Surveillance of Plasmodium falciparum Drug Resistance Markers in Clinical Samples from Botswana

(2018) Leabaneng Tawe et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

No polymorphisms in K13-propeller gene associated with artemisinin resistance in Plasmodium falciparum isolated from Brazzaville, Republic of Congo

(2018) Pembe Issamou Mayengue et al.   BMC INFECTIOUS DISEASES

Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania

(2018) Mwaka A. Kakolwa et al.   MALARIA JOURNAL

Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility

(2018) Allison R. Demas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative pathway to reduced artemisinin susceptibility in Plasmodium falciparum

(2018) Ryan C. Henrici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Status of Artemisinin Resistance in Malaria Parasite Plasmodium falciparum from Molecular Analyses of the Kelch13 Gene in Southwestern Nigeria

(2018) Mary Aigbiremo Oboh et al.   Biomed Research International

Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

(2017) Dorothy E. Loy et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Absence of association between polymorphisms in the K13 gene and the presence of Plasmodium falciparum parasites at day 3 after treatment with artemisinin derivatives in Senegal

(2017) Marylin Madamet et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar

(2017) Craig A. Bonnington et al.   MALARIA JOURNAL

Absence of in vivo selection for K13 mutations after artemether–lumefantrine treatment in Uganda

(2017) Betty Balikagala et al.   MALARIA JOURNAL

Reduced ex vivo susceptibility of Plasmodium falciparum after oral artemether–lumefantrine treatment in Mali

(2017) Souleymane Dama et al.   MALARIA JOURNAL

Molecular surveillance of Plasmodium falciparum drug resistance in the Republic of Congo: four and nine years after the introduction of artemisinin-based combination therapy

(2017) Felix Koukouikila-Koussounda et al.   MALARIA JOURNAL

Efficacy of artemether–lumefantrine, artesunate–amodiaquine, and dihydroartemisinin–piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in Angola, 2015

(2017) Mateusz M. Plucinski et al.   MALARIA JOURNAL

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa

(2017) Feng Lu et al.   NEW ENGLAND JOURNAL OF MEDICINE

PRISMA statement and PROSPERO

(2017) Wanderley Marques Bernardo   International Braz J Urol

Antimalarial Drug Resistance: A Threat to Malaria Elimination

(2017) Didier Menard et al.   Cold Spring Harbor Perspectives in Medicine

Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study

(2017) Tobias O. Apinjoh et al.   Infectious Diseases of Poverty

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo

(2017) Dieudonné Makaba Mvumbi et al.   PLoS One

West Africa International Centers of Excellence for Malaria Research: Drug Resistance Patterns to Artemether–Lumefantrine in Senegal, Mali, and The Gambia

(2016) Baba Dieye et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A Unique Plasmodium falciparum K13 Gene Mutation in Northwest Ethiopia

(2016) Abebe Genetu Bayih et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Artemisinin Resistance–Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010–2015

(2016) Costanza Tacoli et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies

(2016) Toshihiro Mita et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy

(2016) Mónica Guerra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prevalence of K13-propeller gene polymorphisms among Plasmodium falciparum parasites isolated from adult symptomatic patients in northern Uganda

(2016) Moses Ocan et al.   BMC INFECTIOUS DISEASES

Insight into k13-propeller gene polymorphism and ex vivo DHA-response profiles from Cameroonian isolates

(2016) Sandie Menard et al.   MALARIA JOURNAL

Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

(2016) Julian Muwanguzi et al.   MALARIA JOURNAL

Therapeutic efficacy trial of artemisinin-based combination therapy for the treatment of uncomplicated malaria and investigation of mutations in k13 propeller domain in Togo, 2012–2013

(2016) Améyo M. Dorkenoo et al.   MALARIA JOURNAL

A Worldwide Map ofPlasmodium falciparumK13-Propeller Polymorphisms

(2016) Didier Ménard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Limited artemisinin resistance-associated polymorphisms in Plasmodium falciparum K13-propeller and PfATPase6 gene isolated from Bioko Island, Equatorial Guinea

(2016) Jian Li et al.   International Journal for Parasitology-Drugs and Drug Resistance

Polymorphisms in the K13-Propeller Gene in Artemisinin-Susceptible Plasmodium falciparum Parasites from Bougoula-Hameau and Bandiagara, Mali

(2015) Amed Ouattara et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

In Vitroand Molecular Surveillance for Antimalarial Drug Resistance in Plasmodium falciparum Parasites in Western Kenya Reveals Sustained Artemisinin Sensitivity and Increased Chloroquine Sensitivity

(2015) Naomi W. Lucchi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of Mutations in the K13 Propeller Gene of Plasmodium falciparum Isolates from Dakar, Senegal, in 2013-2014

(2015) Agathe Boussaroque et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays

(2015) Roland A. Cooper et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014

(2015) Marylin Torrentino-Madamet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites

(2015) Toshihiro Mita et al.   Expert Review of Anti-Infective Therapy

Evaluation of artemether-lumefantrine efficacy in the treatment of uncomplicated malaria and its association with pfmdr1, pfatpase6 and K13-propeller polymorphisms in Luanda, Angola

(2015) Kinanga Kiaco et al.   MALARIA JOURNAL

Prevalence of K13-propeller polymorphisms in Plasmodium falciparum from China-Myanmar border in 2007–2012

(2015) Zenglei Wang et al.   MALARIA JOURNAL

Pooled Sequencing and Rare Variant Association Tests for Identifying the Determinants of Emerging Drug Resistance in Malaria Parasites

(2015) Ian H. Cheeseman et al.   MOLECULAR BIOLOGY AND EVOLUTION

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

(2015) S. Bhatt et al.   NATURE

Genetic architecture of artemisinin-resistant Plasmodium falciparum

(2015) Olivo Miotto et al.   NATURE GENETICS

Malaria medicines: a glass half full?

(2015) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy

(2015) Bo Huang et al.   Parasites & Vectors

Polymorphisms in Plasmodium falciparum K13-Propeller in Angola and Mozambique after the Introduction of the ACTs

(2015) Carlos Escobar et al.   PLoS One

Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Malaria in Children in Zaire and Uíge Provinces, Angola

(2014) Mateusz M. Plucinski et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study

(2014) Steve M. Taylor et al.   JOURNAL OF INFECTIOUS DISEASES

Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012–2013

(2014) Marylin Torrentino-Madamet et al.   MALARIA JOURNAL

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphisms in K13 and Falcipain-2 Associated with Artemisinin Resistance Are Not Prevalent in Plasmodium falciparum Isolated from Ugandan Children

(2014) Melissa D. Conrad et al.   PLoS One

K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

(2014) J. Straimer et al.   SCIENCE

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

(2013) Olivo Miotto et al.   NATURE GENETICS

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

(2012) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

(2011) Jennifer A Flegg et al.   MALARIA JOURNAL

Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism

(2010) B. Witkowski et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses

(2010) Andreas Stang   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Intrahost modeling of artemisinin resistance in Plasmodium falciparum

(2010) S. Saralamba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE