Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy

Longitudinal serum autoantibody repertoire profiling identifies surgery-associated biomarkers in lung adenocarcinoma

(2020) Yang Li et al.   EBioMedicine

Generating high quality libraries for DIA MS with empirically corrected peptide predictions

(2020) Brian C. Searle et al.   Nature Communications

Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis

(2020) Michael L. Merchant et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients.

(2020) Sanjeev Sethi et al.   KIDNEY INTERNATIONAL

Identification of Novel Native Autoantigens in Rheumatoid Arthritis

(2020) Thomas B. G. Poulsen et al.   Biomedicines

NELL1 is a target antigen in malignancy-associated membranous nephropathy

(2020) Tiffany Caza et al.   KIDNEY INTERNATIONAL

Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells

(2019) Yasuhiro Yoshimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exostosin 1/Exostosin 2–Associated Membranous Nephropathy

(2019) Sanjeev Sethi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning

(2019) Siegfried Gessulat et al.   NATURE METHODS

Neural epidermal growth factor-like 1 protein (NELL-1) associated membranous nephropathy

(2019) Sanjeev Sethi et al.   KIDNEY INTERNATIONAL

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes

(2018) Markus M. Rinschen et al.   Cell Reports

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

(2018) Rajasree Menon et al.   DEVELOPMENT

Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry

(2018) Brian C. Searle et al.   Nature Communications

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

(2018) Lorna J. Hale et al.   Nature Communications

Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy

(2017) Arash Zandian et al.   JOURNAL OF PROTEOME RESEARCH

LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease

(2017) Christopher P. Larsen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

PLA2R and THSD7A: Disparate Paths to the Same Disease?

(2017) Laurence H. Beck   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

High-Temperature Requirement A1 (Htra1) - A Novel Regulator of Canonical Wnt Signaling

(2017) Oriane Globus et al.   Scientific Reports

PLA2R binds to the annexin A2-S100A10 complex in human podocytes

(2017) Maryline Fresquet et al.   Scientific Reports

Autoantibody targets in vaccine-associated narcolepsy

(2016) Anna Häggmark-Månberg et al.   AUTOIMMUNITY

Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling

(2016) Ronald Sjöberg et al.   New Biotechnology

Determination of B-Cell Epitopes in Patients with Celiac Disease: Peptide Microarrays

(2016) Rok Seon Choung et al.   PLoS One

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy

(2015) Takamasa Iwakura et al.   PLoS One

Glomerular Cell Cross-Talk Influences Composition and Assembly of Extracellular Matrix

(2014) A. Byron et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy

(2014) Nicola M. Tomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease

(2014) Hakryul Jo et al.   PLoS One

A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

(2014) M. Delville et al.   Science Translational Medicine

Mass spectrometry based proteomics in the diagnosis of kidney disease

(2013) Sanjeev Sethi et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

(2013) Marco Prunotto et al.   Journal of Proteomics

Structural and Functional Analysis of HtrA1 and Its Subdomains

(2012) Charles Eigenbrot et al.   STRUCTURE

Computational analysis of high-density peptide microarray data with application from systemic sclerosis to multiple sclerosis

(2011) Michael Hecker et al.   AUTOIMMUNITY REVIEWS

High Temperature Requirement Factor A1 (HTRA1) Gene Regulates Angiogenesis through Transforming Growth Factor-β Family Member Growth Differentiation Factor 6

(2011) Li Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of HTRA1 Leads to Ultrastructural Changes in the Elastic Layer of Bruch's Membrane via Cleavage of Extracellular Matrix Components

(2011) Sarah Vierkotten et al.   PLoS One

Expression and Functional Significance of HtrA1 Loss in Endometrial Cancer

(2010) S. A. Mullany et al.   CLINICAL CANCER RESEARCH

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

(2010) Benjamin Hoy et al.   EMBO REPORTS

The incidence of primary glomerulonephritis worldwide: a systematic review of the literature

(2010) A. McGrogan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Identification of Cross-Reactive Epitopes on the Conserved 47-Kilodalton Antigen of Orientia tsutsugamushi and Human Serine Protease

(2009) H.-W. Chen et al.   INFECTION AND IMMUNITY

Serine Protease HtrA1 Associates with Microtubules and Inhibits Cell Migration

(2009) J. Chien et al.   MOLECULAR AND CELLULAR BIOLOGY

M-Type Phospholipase A2Receptor as Target Antigen in Idiopathic Membranous Nephropathy

(2009) Laurence H. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

A human glomerular SAGE transcriptome database

(2009) Jenny Nyström et al.   BMC Nephrology

Alleles in the HtrA Serine Peptidase 1 Gene Alter the Risk of Neovascular Age-Related Macular Degeneration

(2008) Margaret M. DeAngelis et al.   OPHTHALMOLOGY