The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling

Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update

(2016) Y H Lee et al.   LUPUS

Dendritic Cells in Systemic Lupus Erythematosus: From Pathogenic Players to Therapeutic Tools

(2016) Jared Klarquist et al.   MEDIATORS OF INFLAMMATION

Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells

(2016) Xiaofeng Liao et al.   Journal of Immunology Research

From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation

(2015) T. Moroy et al.   BLOOD

Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases

(2015) Jessica A. Hamerman et al.   IMMUNOLOGICAL REVIEWS

Age-associated B cells: key mediators of both protective and autoreactive humoral responses

(2015) Martin S. Naradikian et al.   IMMUNOLOGICAL REVIEWS

Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus

(2015) Kongyang Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

(2015) Kira Rubtsova et al.   JOURNAL OF IMMUNOLOGY

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

(2015) Umeharu Ohto et al.   NATURE

Defects in Germinal Center Selection in SLE

(2015) Megan Woods et al.   Frontiers in Immunology

TLR Agonists Promote Marginal Zone B Cell Activation and Facilitate T-Dependent IgM Responses

(2014) A. V. Rubtsov et al.   JOURNAL OF IMMUNOLOGY

B Cell–Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers

(2014) Chetna Soni et al.   JOURNAL OF IMMUNOLOGY

Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus

(2014) C. Enevold et al.   MOLECULAR BIOLOGY REPORTS

TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice

(2014) B. Desnues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment

(2014) Teja Celhar et al.   Frontiers in Pharmacology

Human B-1 cells take the stage

(2013) Thomas L. Rothstein et al.   Annals of the New York Academy of Sciences

Gr-1highCD11b+ Cells Suppress B Cell Differentiation and Lupus-like Disease in Lupus-Prone Male Mice

(2013) Abhishek Trigunaite et al.   ARTHRITIS AND RHEUMATISM

Role of neutrophils in systemic autoimmune diseases

(2013) Mariana J Kaplan   ARTHRITIS RESEARCH & THERAPY

Snail/Gfi-1 (SNAG) family zinc finger proteins in transcription regulation, chromatin dynamics, cell signaling, development, and disease

(2012) Cindy Chiang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

(2012) Diana Ordoñez-Rueda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

(2011) Y. Hao et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

(2011) Ryutaro Fukui et al.   IMMUNITY

Toll-Like Receptor Agonists Synergize with CD40L to Induce Either Proliferation or Plasma Cell Differentiation of Mouse B Cells

(2011) Emmanuelle Boeglin et al.   PLoS One

Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation

(2011) Tarik Möröy et al.   SEMINARS IN IMMUNOLOGY

TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study

(2011) Aya Kawasaki et al.   ARTHRITIS RESEARCH & THERAPY

Gfi1–cells and circuits: unraveling transcriptional networks of development and disease

(2010) James D Phelan et al.   CURRENT OPINION IN HEMATOLOGY

Endogenous toll-like receptor ligands and their biological significance

(2010) Li Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gfi1 and Gfi1b: key regulators of hematopoiesis

(2010) L T van der Meer et al.   LEUKEMIA

Zinc Finger Protein Gfi1 Controls the Endotoxin-Mediated Toll-Like Receptor Inflammatory Response by Antagonizing NF- B p65

(2010) E. Sharif-Askari et al.   MOLECULAR AND CELLULAR BIOLOGY

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

(2010) N. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

(2009) Marie-Laure Santiago-Raber et al.   JOURNAL OF AUTOIMMUNITY

The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcripts

(2008) Emeka Igwe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY