Article
Chemistry, Multidisciplinary
Polyxeni Spiliopoulou, Spyridon Methenitis, Nikolaos Zaras, Angeliki-Nikoletta Stasinaki, Maria Krekoukia, Stavroula Tsitkanou, Gerasimos Terzis
Summary: The aim of this study was to determine the best surrogate of quadriceps hypertrophy by evaluating the four muscle heads of the quadriceps femoris using ultrasonography. The results suggest that changes in muscle hypertrophy in the vastus lateralis and vastus intermedius can significantly predict overall quadriceps hypertrophy in response to resistance training.
APPLIED SCIENCES-BASEL
(2022)
Article
Physiology
Yuxiao Guo, Eleanor J. Jones, Thomas B. Inns, Isabel A. Ely, Daniel W. Stashuk, Daniel J. Wilkinson, Kenneth Smith, Jessica Piasecki, Bethan E. Phillips, Philip J. Atherton, Mathew Piasecki
Summary: Despite males typically exhibiting greater muscle strength and fatigability than females, this study found sex-based differences in neuromuscular recruitment strategies. Females produce muscle force through smaller motor units discharging at higher rates. However, both sexes show similar strategies in increasing force production from low- to mid-level contractions.
Article
Orthopedics
Conglei Dong, Ming Li, Kuo Hao, Chao Zhao, Kang Piao, Wei Lin, Chongyi Fan, Yingzhen Niu, Wang Fei
Summary: In patients with patellofemoral pain syndrome, atrophy of the vastus medialis obliquus and vastus lateralis muscles was found in sections 0-20 mm above the upper pole of the patella, with the atrophy of the vastus medialis obliquus being more pronounced than that of the vastus lateralis muscle.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Geriatrics & Gerontology
Joey S. J. Smeets, Astrid M. H. Horstman, David P. J. van Dijk, Astrid G. M. van Boxtel, Joost F. ter Woorst, Steven W. M. Olde Damink, Olaf E. M. G. Schijns, Luc J. C. van Loon
Summary: This study revealed that post-absorptive muscle protein synthesis rates are higher in the rectus abdominis compared to the vastus lateralis, while there was no significant difference in synthesis rates between the vastus lateralis and pectoralis major or temporalis muscles. Sampled muscle tissue protein synthesis rates obtained during surgery may not necessarily reflect appendicular skeletal muscle protein synthesis rates.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Orthopedics
Marion Crouzier, Francois Hug, Frances T. Sheehan, Natalie J. Collins, Kay Crossley, Kylie Tucker
Summary: This study aimed to determine whether there is a difference in the torque distribution between the vastus medialis and vastus lateralis in adolescents with and without patellofemoral pain. The results showed that there was no decreased contribution of the vastus medialis to knee extension torque in adolescents with patellofemoral pain compared to controls.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Biophysics
Theresa Domroes, Gunnar Laube, Sebastian Bohm, Adamantios Arampatzis, Falk Mersmann
Summary: The study investigated the applicability of a simplified approach for muscle volume assessment in early-adolescent boys, showing that a cohort-specific shape factor should be used, as muscle volumes assessed with this factor were not significantly different from measured volumes.
JOURNAL OF BIOMECHANICS
(2021)
Article
Biophysics
Bryan Yu, Walter Herzog
Summary: The study aimed to determine the in vivo operating range of the vastus lateralis (VL) muscle during speed skating imitation and compare it to the muscle's force-length relationship. The results showed that the VL muscle works at sub-optimal length during the gliding phase of skating, but at optimal length for maximal force production during the crucial pushoff phase.
JOURNAL OF BIOMECHANICS
(2023)
Article
Medicine, Research & Experimental
Marta Kulich, Gabriel Gomez, Daniel Kwon
Summary: Fibromatosis colli (FC) is a fibroblastic contracture of the sternocleidomastoid muscle that causes a neck mass and torticollis. Most cases can be resolved with conservative measures, but surgery may be needed for persistent disease. This case study presents a novel application of the innervated vastus lateralis free flap for complete excision and reconstruction of a large FC in a 4-year-old patient who did not respond to conservative treatment or surgical release.
Article
Chemistry, Multidisciplinary
Sergio Perez, Alex A. Olmos, Stephanie A. Sontag, Mandy E. Parra, Hannah L. Dimmick, Adam J. Sterczala, Jonathan D. Miller, Jake A. Deckert, Trent J. Herda, Michael A. Trevino
Summary: This study examined the effects of cycling training on the MMG(MDF)-torque relationships of the vastus lateralis. The results showed that after 10 weeks of cycling training, different motor unit control strategies were observed between sexes and between muscle actions for the vastus lateralis during a moderate-intensity contraction.
APPLIED SCIENCES-BASEL
(2022)
Article
Endocrinology & Metabolism
Shi-en Fu, Rou-mei Wang, Xing-huan Liang, Jing Xian, Jie Pan, Xue-lan Chen, Cheng-cheng Qiu, Zhi-ping Tang, Ying-fen Qin, Hai-yan Yang, Li-li Huang, Ya-qi Kuang, Yan Ma, Zuo-jie Luo
Summary: This study evaluated CTM in patients with hyperthyroidism using ultrasound and identified cutoff values for ultrasonic muscle parameters for CTM diagnosis. The findings suggest that ultrasound measurement of muscular parameters, especially in the VM, is a valid and feasible way of diagnosing and characterizing possible CTM in hyperthyroidism.
ENDOCRINE CONNECTIONS
(2023)
Article
Physiology
Fang Qiu, Xiaodong Liu, Yilin Xu, Lijun Shi, Xinjun Sheng, Chen Chen
Summary: This study compares the neural adaptations in motor unit properties between sprinters and nonathletes and demonstrates the potential of EMG decomposition in physiological investigations.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Rehabilitation
Mario Parstorfer, Francesca Profit, Nadine Weiberg, Michaela Wehrstein, Alexander Barie, Birgit Friedmann-Bette
Summary: This study investigated satellite cell content and function of the vastus lateralis muscle after anterior ligament reconstruction. The findings showed that satellite cell apoptosis increased while the total satellite cell number decreased post-reconstruction, suggesting a potential explanation for prolonged quadriceps muscle atrophy.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Chemistry, Analytical
Alfredo Bravo-Sanchez, Pablo Abian, Jorge Sanchez-Infante, Paula Esteban-Gacia, Fernando Jimenez, Javier Abian-Vicen
Summary: This study evaluated the reliability of four methods for assessing vastus lateralis (VL) stiffness and found that myotonometry and tensiomyography (TMG) showed the best inter-day reliability. Myotonometry stiffness values were influenced by structural variables, while significant correlations were found between myotonometry and VL thickness, adipose tissue thickness, and superficial connective tissue thickness.
Article
Physiology
Maximiliano Espinosa-Ramirez, Eduardo Moya-Gallardo, Felipe Araya-Roman, Santiago Riquelme-Sanchez, Guido Rodriguez-Garcia, W. Darlene Reid, Gines Viscor, Oscar F. Araneda, Luigi Gabrielli, Felipe Contreras-Briceno
Summary: This study found that during incremental physical exercise, women experienced a more significant decrease in oxygen saturation in respiratory muscles, while men showed a more significant decrease in oxygen saturation in locomotor muscles. Women had a higher cost of breathing, while men had a higher peripheral load.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Amelie Werkhausen, Oyvind Gloersen, Antoine Nordez, Goran Paulsen, Jens Bojsen-Moller, Olivier R. Seynnes
Summary: In this study, the relationship between rate of force development (RFD) and muscle architecture and dynamics was investigated. It was found that RFD was positively correlated to fascicle shortening velocity, but not to optimal fascicle length or architectural gear ratio. The results highlight the importance of fascicle shortening velocity and force-length-velocity properties for rapid force production, and suggest a possible role of fascicle rotation.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
A. Nolan, R. Brett, J. A. Strauss, C. E. Stewart, S. O. Shepherd
Summary: Short-term supplementation with anthocyanin-rich New Zealand blackcurrant extract improved insulin sensitivity and postprandial glucose responses in overweight individuals, while a single dose did not have a significant effect. Continuous glucose monitoring enabled the observation of the effects of the extract under free-living conditions, indicating the potential of anthocyanin-rich supplements in reducing insulin resistance.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Katie L. Whytock, Sam O. Shepherd, Matt Cocks, Anton J. M. Wagenmakers, Juliette A. Strauss
Summary: The study found that short-term high-fat, high-calorie diets did not significantly impact insulin sensitivity, metabolic flexibility, or arterial stiffness in young healthy males and females. There were differences in fat distribution between males and females, with males showing a more significant increase in trunk to leg fat mass ratio.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Daniel J. Owens, Julien Messeant, Sophie Moog, Mark Viggars, Arnaud Ferry, Kamel Mamchaoui, Emmanuelle Lacene, Norma Romero, Astrid Brull, Gisele Bonne, Gillian Butler-Browne, Catherine Coirault
Summary: Laminopathies are a group of disorders caused by mutations in the LMNA gene, particularly affecting skeletal and cardiac muscles. Mutations in LMNA-CMD lead to impaired myogenic fusion, defective protein synthesis, and neuromuscular junction remodeling. This study suggests that A-type lamins play a role in mechanosignaling pathways in skeletal muscle growth.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Physiology
Mohd-Firdaus Maasar, Daniel C. Turner, Piotr P. Gorski, Robert A. Seaborne, Juliette A. Strauss, Sam O. Shepherd, Matt Cocks, Nicolas J. Pillon, Juleen R. Zierath, Andrew T. Hulton, Barry Drust, Adam P. Sharples
Summary: The study found that different types of exercises, especially change of direction exercise, may induce higher exercise intensity and greater genome-wide hypomethylation features post-exercise, which are associated with changes in gene expression levels related to exercise adaptation.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Philipp Baumert, S. Temple, J. M. Stanley, M. Cocks, J. A. Strauss, S. O. Shepherd, B. Drust, M. J. Lake, C. E. Stewart, R. M. Erskine
Summary: The study reveals that repeated maximal sprints can lead to neuromuscular fatigue in hamstring muscles, causing both immediate strength loss linked to central and peripheral fatigue and prolonged strength loss associated with muscle damage indicators. The findings suggest that kinematic changes after sprinting may protect fatigued hamstrings, while factors like muscle cross-sectional area and myoblast:fibroblast ratio could aid in muscle recovery within 48 hours post-sprinting.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Jamie N. Pugh, Marie M. Phelan, Eva Caamano-Gutierrez, S. Andy Sparks, James P. Morton, Graeme L. Close, Daniel J. Owens
Summary: This study investigated the impact of probiotic supplementation on systemic metabolism in endurance athletes post-Marathon. The findings suggest that probiotic supplementation can alter serum metabolome post-Marathon, but has no discernible effect on muscle metabolism.
Article
Biochemistry & Molecular Biology
James F. Hudson, Marie M. Phelan, Daniel J. Owens, James P. Morton, Graeme L. Close, Claire E. Stewart
Summary: This study used untargeted metabolomics to investigate metabolic fluctuations caused by competitive rugby, revealing that high-intensity sports meet acute energy needs through glycolysis, the TCA cycle, and gluconeogenesis. During the recovery period after matches, re-entry into gluconeogenesis is observed along with markers of oxidative stress, structural protein degradation, and reduced fatty acid metabolism.
Review
Nutrition & Dietetics
J. S. Barrett, K. L. Whytock, J. A. Strauss, A. J. M. Wagenmakers, S. O. Shepherd
Summary: Large intramuscular triglyceride (IMTG) stores have been linked to insulin resistance, but it is now known that it is not the IMTG content itself, but the presence of harmful lipid metabolites that causes insulin resistance. Mechanistic differences between sedentary obese individuals and trained athletes determine their capacity for IMTG synthesis and breakdown. Improving IMTG turnover is important for preventing insulin resistance in sedentary, overweight, and obese populations.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Multidisciplinary Sciences
Katie L. Hesketh, Hannah Church, Florence Kinnafick, Sam O. Shepherd, Anton J. M. Wagenmakers, Matthew Cocks, Juliette A. Strauss
Summary: This study found that HIIT protocols available on social media offer an interesting real-world alternative for promoting exercise participation. Future studies should continue to investigate these highly popular and practical HIIT protocols.
Article
Physiology
Katie Hesketh, Helen Jones, Florence Kinnafick, Sam O. Shepherd, Anton J. M. Wagenmakers, Juliette A. Strauss, Matthew Cocks
Summary: Exercise referral schemes (ERS) are used to promote physical activity in primary care, traditionally conducted in a gym setting with moderate-intensity continuous training. This study evaluated the use of home-based high-intensity interval training (Home-HIIT) for individuals within ERS, and found that both Home-HIIT and MICT led to similar improvements in cardiorespiratory fitness, with adherence rates and outcomes maintained at 3-month follow-up. The study suggests that although not superior, Home-HIIT could be an effective and popular additional exercise choice for patients within primary care based ERS.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cell Biology
Philipp Baumert, Matthew Cocks, Juliette A. Strauss, Sam O. Shepherd, Barry Drust, Mark J. Lake, Claire E. Stewart, Robert M. Erskine
Summary: This study identified a polygenic profile associated with muscle weakness and poorer recovery following EIMD, and provided evidence for a novel TTN gene-cell-skeletal muscle mechanism that may help explain some of the interindividual variability in the response to EIMD.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Review
Physiology
Tanja Oosthuyse, Juliette A. Strauss, Anthony C. Hackney
Summary: This review outlines recent advances in understanding the molecular signaling of ovarian hormones and menstrual phase variations in exercise metabolism. The study found that estrogen and progesterone have different effects on exercise performance and metabolism during different phases of the menstrual cycle, which is important for training and performance of female athletes.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Rebecca Law, Emily F. P. Jevons
Summary: This study aimed to investigate the perceived impact of social media use (SMU) on disordered eating in nutrition and dietetics students. The findings suggested that SMU had both positive and negative effects on students' eating behavior and diet quality. Negative impacts, such as misinformation, body image dissatisfaction, social pressures, and disordered eating, were also attributed to course content. Future research should explore ways to mitigate the negative impact of SMU and course content on disordered eating in this population.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2023)