Disease etiology and diagnosis by TCR repertoire analysis goes viral

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis

(2016) Maura Rossetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+T cell receptor alpha repertoire following allogeneic transplantation

(2016) C. S. Link et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients

(2016) Thi HO Nguyen et al.   IMMUNOLOGY AND CELL BIOLOGY

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

(2016) David K. Cole et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutual Interference between Cytomegalovirus and Reconstitution of Protective Immunity after Hematopoietic Cell Transplantation

(2016) Matthias J. Reddehase   Frontiers in Immunology

Intrathecal T-cell clonal expansions in patients with multiple sclerosis

(2016) Alessandra de Paula Alves Sousa et al.   Annals of Clinical and Translational Neurology

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

(2015) Yvonne Suessmuth et al.   BLOOD

Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

(2015) Michelle A Neller et al.   IMMUNOLOGY AND CELL BIOLOGY

High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+T cells

(2014) Andreas Lossius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunological characteristics and T-cell receptor clonal diversity in children with systemic juvenile idiopathic arthritis undergoing T-cell-depleted autologous stem cell transplantation

(2014) Qiong Wu et al.   IMMUNOLOGY

TCR  -Chain Sharing in Human CD8+ T Cell Responses to Cytomegalovirus and EBV

(2014) V. Venturi et al.   JOURNAL OF IMMUNOLOGY

Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing

(2014) I. V. Zvyagin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep sequencing of the T-cell receptor repertoire in CD8+ T-large granular lymphocyte leukemia identifies signature landscapes

(2013) M. J. Clemente et al.   BLOOD

CMV reactivation after allogeneic HCT and relapse risk: evidence for early protection in acute myeloid leukemia

(2013) M. L. Green et al.   BLOOD

Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop

(2013) Dhruv K. Sethi et al.   Nature Communications

T-cell receptor repertoire analysis in monozygotic twins concordant and discordant for type 1 diabetes

(2012) Claudio Fozza et al.   IMMUNOBIOLOGY

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

(2012) D. Koning et al.   JOURNAL OF IMMUNOLOGY

High-Throughput Sequencing Detects Minimal Residual Disease in Acute T Lymphoblastic Leukemia

(2012) D. Wu et al.   Science Translational Medicine

Deep Sequencing of Antiviral T-Cell Responses to HCMV and EBV in Humans Reveals a Stable Repertoire That Is Maintained for Many Years

(2012) P. L. Klarenbeek et al.   PLoS Pathogens

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large TCR Diversity of Virus-Specific CD8 T Cells Provides the Mechanistic Basis for Massive TCR Renewal after Antigen Exposure

(2011) I. Miconnet et al.   JOURNAL OF IMMUNOLOGY

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

(2010) John J. Miles et al.   PLoS Pathogens

The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor

(2009) P. Scheinberg et al.   BLOOD

Intrathecal immune responses to EBV in early MS

(2009) Emilie Jaquiéry et al.   EUROPEAN JOURNAL OF IMMUNOLOGY