What can cerebrospinal fluid testing and brain autopsies tell us about viral neuroinvasion of SARS‐CoV‐2

Cerebrospinal fluid in COVID-19: A systematic review of the literature

(2021) Ariane Lewis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neurological involvement in the respiratory manifestations of COVID-19 patients

(2021) Bai-Hong Tan et al.   Aging-US

The neuroinvasive potential of SARS‐CoV2 may be at least partially responsible for the respiratory failure of COVID‐19 patients

(2020) Yan‐Chao Li et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology

(2020) R. Ross Reichard et al.   ACTA NEUROPATHOLOGICA

SARS-CoV-2 Detected in Cerebrospinal Fluid by PCR in a Case of COVID-19 Encephalitis

(2020) Y. Hanna Huang et al.   BRAIN BEHAVIOR AND IMMUNITY

Meningoencephalitis without respiratory failure in a young female patient with COVID-19 infection in Downtown Los Angeles, early April 2020

(2020) Lisa Duong et al.   BRAIN BEHAVIOR AND IMMUNITY

Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China

(2020) Yan Deng et al.   CHINESE MEDICAL JOURNAL

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

(2020) Xiaohua Chen et al.   CLINICAL INFECTIOUS DISEASES

CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city

(2020) Rui Zhang et al.   EUROPEAN RADIOLOGY

Post‐mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction

(2020) T. Menter et al.   HISTOPATHOLOGY

Pulmonary and systemic involvement of COVID‐19 assessed by ultrasound‐guided minimally invasive autopsy

(2020) Amaro Nunes Duarte‐Neto et al.   HISTOPATHOLOGY

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2

(2020) Takeshi Moriguchi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Postmortem Examination of Patients With COVID-19

(2020) Tina Schaller et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The emergence of a novel coronavirus (SARS‐CoV‐2) disease and their neuroinvasive propensity may affect in COVID‐19 patients

(2020) H.C. Yashavantha Rao et al.   JOURNAL OF MEDICAL VIROLOGY

Central Nervous System Involvement by Severe Acute Respiratory Syndrome Coronavirus ‐2 (SARS‐CoV‐2)

(2020) Alberto Paniz‐Mondolfi et al.   JOURNAL OF MEDICAL VIROLOGY

Response to Commentary on “The neuroinvasive potential of SARS-CoV-2 may play a role in the respiratory failure of COVID-19 patients”

(2020) Yan-Chao Li et al.   JOURNAL OF MEDICAL VIROLOGY

COVID-19-associated acute disseminated encephalomyelitis (ADEM)

(2020) Timothy Parsons et al.   JOURNAL OF NEUROLOGY

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Focal Cerebral Arteriopathy in a COVID-19 Pediatric Patient

(2020) Seyed Mohammad Mousavi Mirzaee et al.   RADIOLOGY

The mystery of the pandemic's ‘happy hypoxia’

(2020) Jennifer Couzin-Frankel   SCIENCE

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

Acute disseminated encephalomyelitis after SARS-CoV-2 infection

(2020) Giovanni Novi et al.   Neurology-Neuroimmunology & Neuroinflammation

Computing the Effects of SARS-CoV-2 on Respiration Regulatory Mechanisms in COVID-19

(2020) Abdul Mannan Baig   ACS Chemical Neuroscience

Pathophysiology of the COVID-19 – entry to the CNS through the nose

(2020) Jukka Ylikoski et al.   ACTA OTO-LARYNGOLOGICA

Allograft infiltration and meningoencephalitis by SARS‐CoV‐2 in a pancreas‐kidney transplant recipient

(2020) Timm H. Westhoff et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Neuropathologic features of four autopsied COVID‐19 patients

(2020) Jonas Kantonen et al.   BRAIN PATHOLOGY

Encephalomyelitis associated with Covid-19 infection: case report

(2020) Gulden Demirci Otluoglu et al.   BRITISH JOURNAL OF NEUROSURGERY

A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review

(2020) Nima Fadakar et al.   CEREBELLUM

Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid

(2020) Otávio de Melo Espíndola et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China

(2020) Guqin Zhang et al.   JOURNAL OF CLINICAL VIROLOGY

The possible impairment of respiratory‐related neural loops may be associated with the silent pneumonia induced by SARS‐CoV‐2

(2020) Bai‐Hong Tan et al.   JOURNAL OF MEDICAL VIROLOGY

First case of SARS-COV-2 sequencing in cerebrospinal fluid of a patient with suspected demyelinating disease

(2020) Renan Barros Domingues et al.   JOURNAL OF NEUROLOGY

Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms

(2020) Bernhard Neumann et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

(2020) Benjamin T Bradley et al.   LANCET

Early evidence of pronounced brain involvement in fatal COVID-19 outcomes

(2020) Claus Hann von Weyhern et al.   LANCET

First ultrastructural autoptic findings of SARS -Cov-2 in olfactory pathways and brainstem

(2020) Gaetano Bulfamante et al.   Minerva Anestesiologica

Acute necrotizing encephalopathy with SARS-CoV-2 RNA confirmed in cerebrospinal fluid

(2020) Johan Virhammar et al.   NEUROLOGY

Headache and impaired consciousness level associated with SARS-CoV-2 in CSF

(2020) José Cebrián et al.   NEUROLOGY

Neuropathological Features of Covid-19

(2020) Isaac H. Solomon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study

(2020) Stéphane Kremer et al.   RADIOLOGY

SARS-CoV-2 Dissemination Through Peripheral Nerves Explains Multiple Organ Injury

(2020) Matija Fenrich et al.   Frontiers in Cellular Neuroscience

Fatal central nervous system co-infection with SARS-CoV-2 and tuberculosis in a healthy child

(2020) Bishara J. Freij et al.   BMC Pediatrics

Brain ischemic injury in CoViD19 infected patients: a series of 10 post‐mortem cases

(2020) Viscardo P. Fabbri et al.   BRAIN PATHOLOGY

COVID‐19 meningitis without pulmonary involvement with positive cerebrospinal fluid PCR

(2020) Zohre Khodamoradi et al.   EUROPEAN JOURNAL OF NEUROLOGY

Evidence of central nervous system infection and neuroinvasive routes, as well as neurological involvement, in the lethality of SARS‐CoV‐2 infection

(2020) Jia‐Mei Liu et al.   JOURNAL OF MEDICAL VIROLOGY

HLA and immunological features of SARS-CoV-2-induced Guillain-Barré syndrome

(2020) Gian Luigi Gigli et al.   NEUROLOGICAL SCIENCES

Brain microvascular occlusive disorder in COVID-19: a case report

(2020) Laura Saitta et al.   NEUROLOGICAL SCIENCES

Neuropathological findings in two patients with fatal COVID‐19

(2020) M. P. Jensen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Invited Review: The spectrum of neuropathology in COVID‐19

(2020) S. Al‐Sarraj et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Large and Small Cerebral Vessel Involvement in Severe COVID-19

(2020) Emanuela Keller et al.   STROKE

Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage

(2020) Osama Al-Dalahmah et al.   Acta Neuropathologica Communications

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

(2020) Jenny Meinhardt et al.   NATURE NEUROSCIENCE

Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis

(2011) Marija Djukic et al.   JOURNAL OF NEUROLOGY

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

(2008) J. Netland et al.   JOURNAL OF VIROLOGY