Article
Surgery
Mohamad Rassoul Abu-Nuwar, Sven E. Eriksson, Inanc S. Sarici, Ping Zheng, Toshitaka Hoppo, Blair A. Jobe, Shahin Ayazi
Summary: Peroral endoscopic myotomy (POEM) is effective for achalasia, but postoperative gastroesophageal reflux disease (GERD) is a major concern. This study aimed to characterize post-POEM GERD and identify factors influencing its development and severity. Results showed that 38.8% of patients had subjective GERD symptoms, 50.5% had objective GERD, and 19.2% had severe objective GERD.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Article
Gastroenterology & Hepatology
Shinji Nishiwaki, Takuya Kurobe, Atsushi Baba, Hironori Nakamura, Masahide Iwashita, Seiji Adachi, Hiroo Hatakeyama, Takao Hayashi, Teruo Maeda
Summary: DPEJ is a safe and feasible method for enteral feeding, with similar long-term outcomes to PEG. However, specific adverse events associated with DPEJ, such as fistula enlargement and ileus, should be monitored during long-term feeding. A retrospective cohort study found that older age, higher C-reactive protein levels, and diabetes were independent risk factors for mortality after DPEJ.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Pediatrics
Faraz A. Khan, Kelsey Nestor, Asra Hashmi, Saleem Islam
Summary: This report assessed outcomes in infants who underwent GT insertion alone or with concomitant ARP. The study found that preoperative GER was significantly higher in the GT with ARP group, and the postoperative increase in anti-reflux medications was also higher in the GT group. However, there was no significant difference in the need for a secondary procedure between patients who underwent GT alone and those who underwent GT with ARP. Overall, the study suggests that GT insertion can be considered a reasonable approach even in high-risk patients who have already undergone ARP.
FRONTIERS IN PEDIATRICS
(2022)
Article
Surgery
R. M. Juza, S. Docimo, S. Drexel, V Sandoval, J. M. Marks, E. M. Pauli
Summary: Endoscopic rescue is a feasible noninvasive option for PEG tube replacement following early inadvertent PEG tube dislodgement in appropriate clinical settings. A retrospective analysis of cases from two institutions found that PEG rescue was successful in all 11 identified patients, with a mean operative time of 68 minutes and no complications related to the procedure.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Nutrition & Dietetics
Hemant Goyal, Aman Ali, Pardeep Bansal
Summary: Intensive care units (ICU) worldwide are facing challenges with an influx of COVID-19 patients suffering from ventilator-dependent chronic respiratory failure (VDRF). Gastroenterology evaluations are being conducted to provide chronic enteral feeding for these patients through percutaneous endoscopic gastrostomy (PEG) placements, aiming to expedite discharge planning and free up ICU beds for other patients. This multidisciplinary approach of PEG tube placements in patients with SARS-CoV-2-induced chronic VDRF showcases the benefits of continued enteral feeding to reduce complications and shorten hospital stays.
FRONTIERS IN NUTRITION
(2021)
Article
Gastroenterology & Hepatology
Divyanshoo R. Kohli, Craig Smith, Omer Chaudhry, Madhav Desai, Dion DePaolis, Prateek Sharma
Summary: This study compared the safety and efficacy of an introducer-style endoscopic direct PEG (DPEG) and an interventional radiologist guided gastrostomy (IRG) among patients unable to undergo a conventional transoral pull PEG. The results showed that DPEG is a safe and effective alternative for enteral support.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Cardiac & Cardiovascular Systems
Jesse M. P. Rappaport, Siva Raja, Scott Gabbard, Lucy Thuita, Madhusudhan R. Sanaka, Eugene H. Blackstone, Usman Ahmad
Summary: This study evaluated the safety and clinical effectiveness of per-oral endoscopic pyloromyotomy in relieving gastroparesis after lung transplant. The results showed that this procedure can effectively alleviate the symptoms of gastroparesis and also improve gastroesophageal reflux and allograft function.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Nutrition & Dietetics
Rachel Strahm, Manuel Weber, Reiner Wiest, Kai-Uwe Schmitt
Summary: This study examined the effects of early tube feeding compared to tube feeding after 24 hours on clinical parameters. Patients with percutaneous endoscopic gastrostomy (PEG) received tube feeding 4 hours after tube insertion following the updated ESPEN guidelines. An observational study analyzed whether the new scheme affected patient complaints, complications, or hospitalization duration. The study found that the new scheme did not impact patient complaints or complications, but it significantly reduced hospitalization duration.
Article
Pediatrics
Elisa Zambaiti, Calogero Virgone, Silvia Bisoffi, Roberta Stefanizzi, Francesco Fascetti Leon, Piergiorgio Gamba
Summary: This study compared the long-term outcomes of gastrostomy only (GO) to gastrostomy with fundoplication (GF) in neurologically impaired children. The findings suggest that gastrostomy placement alone may not be inferior to gastrostomy plus fundoplication in reducing long-term respiratory-related complications for these children.
Article
Medicine, General & Internal
Shingo Ono, Hiroto Furuhashi, Shunsuke Kisaki, Hideka Horiuchi, Hiroaki Matsui, Akira Dobashi, Hiroya Ojiri, Kazuki Sumiyama
Summary: This study investigated the prognostic factors associated with percutaneous endoscopic gastrostomy (PEG). It found that sarcopenia is negatively correlated with the prognosis after PEG. Among the 127 patients studied, approximately half (56%) had sarcopenia, and the study showed that patients with sarcopenia had shorter median survival time after PEG compared to those without. Therefore, sarcopenia is a predictive indicator of poor prognosis after PEG.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Gastroenterology & Hepatology
Enrique Rodriguez de Santiago, Eduardo Albeniz, Fermin Estremera-Arevalo, Carlos Teruel Sanchez-Vegazo, Vicente Lorenzo-Zuniga
Summary: Gastroesophageal reflux disease is on the rise globally, and for patients with suboptimal response to proton pump inhibitors or concerns about lifelong medication, endoscopic anti-reflux therapies provide a minimally invasive option. The most supported techniques are transoral incisionless fundoplication and nonablative radiofrequency, but the role of endoscopic procedures remains controversial due to limited data and lack of consensus in current clinical guidelines.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Pediatrics
C. Charlotte Jean-Bart, Madeleine Aumar, Delphine Ley, Matthieu Antoine, Emeline Cailliau, Stephanie Coopman, Dominique Guimber, Serge Ganga, Dominique Turck, Frederic Gottrand
Summary: This retrospective study aimed to assess the complications of one-step button percutaneous endoscopic gastrostomy (B-PEG) and identify risk factors for stomal infections or gastropexy complications. A total of 679 children who underwent B-PEG over a 10-year period were included. Early and late complications, as well as patient characteristics and outcomes, were recorded. The study found that major complications were rare, early complications affected 15.9% of the population, and 78.0% experienced late complications. The most common complications were granulation tissue formation, tube dislodgment, and T-fastener complications. Stomal infections occurred in only 3.5% of patients, with young age as a risk factor and underlying neurological disease as a protective factor.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Gastroenterology & Hepatology
Dag Holmberg, Giola Santoni, My Catarina von Euler-Chelpin, Martti Farkkila, Joonas H. Kauppila, John Maret-Ouda, Eivind Ness-Jensen, Jesper Lagergren
Summary: This population-based cohort study conducted in Denmark, Finland, Norway, and Sweden from 1979 to 2018 found that negative upper endoscopy in patients with GERD is associated with a significant and long-lasting decrease in both incidence and mortality of upper gastrointestinal cancer. The risk reduction persisted for at least 5 years in incidence and 10 years in mortality after a negative upper endoscopy.
Article
Gastroenterology & Hepatology
Sydney R. A. Korsunsky, Leonel Camejo, Diep Nguyen, Rahul Mhaskar, Khattiya Chharath, Joy Gaziano, Joel Richter, Vic Velanovich
Summary: This study retrospectively analyzed the clinical evaluation, treatments, and outcomes of patients with hoarseness suspected to be caused by laryngopharyngeal reflux. Among the 134 included patients, most of them experienced improvement during the treatment and evaluation period, but no specific treatment type showed a clear association with the outcomes. Further research is needed to explore diagnostic criteria, efficient clinical evaluation methods, and potential beneficial treatments for laryngopharyngeal reflux.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Gastroenterology & Hepatology
Amol Bapaye, Parag Dashatwar, Siddharth Dharamsi, Rajendra Pujari, Harshal Gadhikar
Summary: This study reported short-term outcomes of POEM+F, showing technical success and significant improvement in dysphagia. The incidence of post-POEM+F GER was low and acceptable, indicating that POEM+F is safe and reproducible.