Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows

Orai calcium release-activated calcium modulator 1 (ORAI1) plays a role in endoplasmic reticulum stress in bovine mammary epithelial cells challenged with physiological levels of ketone bodies

(2020) Bingbing Zhang et al.   JOURNAL OF DAIRY SCIENCE

Endoplasmic Reticulum Stress-induced Upregulation of STARD1 Promotes Acetaminophen-induced Acute Liver Failure

(2019) Sandra Torres et al.   GASTROENTEROLOGY

Fatty acid-induced endoplasmic reticulum stress promoted lipid accumulation in calf hepatocytes, and endoplasmic reticulum stress existed in the liver of severe fatty liver cows

(2019) Yiwei Zhu et al.   JOURNAL OF DAIRY SCIENCE

Interplay of Oxidative Stress, Inflammation, and Autophagy: Their Role in Tissue Injury of the Heart, Liver, and Kidney

(2018) Partha Mukhopadhyay et al.   Oxidative Medicine and Cellular Longevity

Piceatannol attenuates D-GalN/LPS-induced hepatoxicity in mice: Involvement of ER stress, inflammation and oxidative stress

(2018) Jingjing Wen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway

(2018) Li-Yuan Wang et al.   BIOCHEMICAL PHARMACOLOGY

Expression patterns of hepatic genes involved in lipid metabolism in cows with subclinical or clinical ketosis

(2018) Yiwei Zhu et al.   JOURNAL OF DAIRY SCIENCE

Impaired hepatic autophagic activity in dairy cows with severe fatty liver is associated with inflammation and reduced liver function

(2018) Xiliang Du et al.   JOURNAL OF DAIRY SCIENCE

Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketotic cows

(2017) Xiliang Du et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders?

(2017) Jack van Horssen et al.   NEUROSCIENCE LETTERS

Salinomycin induces endoplasmic reticulum stress-mediated autophagy and apoptosis through generation of reactive oxygen species in human glioma U87MG cells

(2017) Sun-Nyoung Yu et al.   ONCOLOGY REPORTS

Accuracy of a cow-side test for the diagnosis of hyperketonemia and hypoglycemia in lactating dairy cows

(2017) K. Macmillan et al.   RESEARCH IN VETERINARY SCIENCE

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

(2017) Xin-Yu Wang et al.   Cell Death & Disease

Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis

(2017) Xiliang Du et al.   Oncotarget

Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review

(2017) Erdi Sozen et al.   Redox Biology

Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

(2016) Ja Hyun Koo et al.   GASTROENTEROLOGY

Inflammation, oxidative stress, apoptosis, and autophagy in diabetes mellitus and diabetic kidney disease: the Four Horsemen of the Apocalypse

(2016) Kultigin Turkmen   INTERNATIONAL UROLOGY AND NEPHROLOGY

Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

(2016) Arvin Iracheta-Vellve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Hydroxybutyrate induces bovine hepatocyte apoptosis via an ROS-p38 signaling pathway

(2016) Yuxiang Song et al.   JOURNAL OF DAIRY SCIENCE

Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress

(2016) Hiromi Kusama et al.   JOURNAL OF GASTROENTEROLOGY

ER stress contributes to alpha-naphthyl isothiocyanate-induced liver injury with cholestasis in mice

(2016) Xiaomin Yao et al.   PATHOLOGY RESEARCH AND PRACTICE

The unfolded protein response and cellular senescence. A Review in the Theme: Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease

(2015) Olivier Pluquet et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Stress and inflammatory gene networks in bovine liver are altered by plane of dietary energy during late pregnancy

(2015) M. Jawad Khan et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1–Xbp1s pathway expedites liver injury

(2015) Chang Yeob Han et al.   GUT

Risk factors for subclinical and clinical ketosis and association with production parameters in dairy cows in the Netherlands

(2015) T. Vanholder et al.   JOURNAL OF DAIRY SCIENCE

The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows

(2015) Heather White   Animals

Up-regulation of endoplasmic reticulum stress induced genes of the unfolded protein response in the liver of periparturient dairy cows

(2014) Denise K Gessner et al.   BMC Veterinary Research

�-Hydroxybutyrate Activates the NF-κB Signaling Pathway to Promote the Expression of Pro-Inflammatory Factors in Calf Hepatocytes

(2014) Xiaoxia Shi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tauroursodeoxycholic Acid Attenuates Progression of Steatohepatitis in Mice Fed a Methionine–Choline-Deficient Diet

(2014) Eun-Ju Cho et al.   DIGESTIVE DISEASES AND SCIENCES

Molecular insights into the mechanisms of liver-associated diseases in early-lactating dairy cows: hypothetical role of endoplasmic reticulum stress

(2014) R. Ringseis et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

A field study to determine the prevalence, dairy herd management systems, and fresh cow clinical conditions associated with ketosis in western European dairy herds

(2014) Anna C. Berge et al.   JOURNAL OF DAIRY SCIENCE

Biomarkers of inflammation, metabolism, and oxidative stress in blood, liver, and milk reveal a better immunometabolic status in peripartal cows supplemented with Smartamine M or MetaSmart

(2014) J.S. Osorio et al.   JOURNAL OF DAIRY SCIENCE

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Liver fat content and lipid metabolism in dairy cows during early lactation and during a mid-lactation feed restriction

(2013) J.J. Gross et al.   JOURNAL OF DAIRY SCIENCE

The association of serum metabolites in the transition period with milk production and early-lactation reproductive performance

(2012) N. Chapinal et al.   JOURNAL OF DAIRY SCIENCE

Alterations of fatty acid β-oxidation capability in the liver of ketotic cows

(2012) P. Li et al.   JOURNAL OF DAIRY SCIENCE

Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice

(2012) Jian-Qing Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The contribution of endoplasmic reticulum stress to liver diseases

(2011) Lily Dara et al.   HEPATOLOGY

Effects of encapsulated niacin on metabolism and production of periparturient dairy cows

(2011) S.D. Morey et al.   JOURNAL OF DAIRY SCIENCE

Influence of a marine algae supplementation on the oxidative status of plasma in dairy cows during the periparturient period

(2011) N. Wullepit et al.   PREVENTIVE VETERINARY MEDICINE

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Genomics of metabolic adaptations in the peripartal cow

(2010) J. J. Loor   Animal

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells

(2010) Xuemei Gu et al.   LIFE SCIENCES

Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells

(2009) Nicolas Dejeans et al.   BIOCHEMICAL PHARMACOLOGY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

A whole-genome assembly of the domestic cow, Bos taurus

(2009) Aleksey V Zimin et al.   GENOME BIOLOGY