Article
Chemistry, Applied
Francisco Jose Diaz-Galiano, Maria Jose Gomez-Ramos, Iciar Beraza, Maria Murcia-Morales, Amadeo R. Fernandez-Alba
Summary: Microwavable plastic food containers can release toxic substances into food. Plastic migrants in food contact materials can react with natural food components and form compounds after cooking. Polypropylene glycol substances have also been found to transfer into food through microwave cooking. Advanced mass spectrometry instrumentation and metabolomics-based strategies are needed to identify these substances.
Article
Biochemistry & Molecular Biology
Pablo Miralles, Vicent Yusa, Yovana Sanchis, Clara Coscolla
Summary: A GC-HRMS analytical method has been developed and validated for the determination of 60 migrant substances in plastic food contact materials, showing satisfactory linearity, precision, and relative recovery. The method was successfully applied to field samples, demonstrating compliance with current European regulations.
Review
Engineering, Environmental
Spyridoula Gerassimidou, Paulina Lanska, John N. Hahladakis, Elena Lovat, Silvia Vanzetto, Birgit Geueke, Ksenia J. Groh, Jane Muncke, Maricel Maffini, Olwenn V. Martin, Eleni Iacovidou
Summary: This study provides a systematic evidence map of the migration of chemicals from PET drink bottles into food, highlighting the challenges and influential factors. While recycling PET bottles is vital for reducing plastic pollution, safety and quality concerns may arise.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Di Feng, Xueyan Li, Xiaojie Fan, Yifan Guo, Jingwei Zhang, Hang Yuan, Wenjuan Wang, Tingting Zhao, Tian Han
Summary: The cytotoxicity and endocrine-disruption activity of 42 food contact silicone products (FCSPs) obtained from the Chinese market were studied. The results showed that 96% of the kitchenwares and 84% of the products showed cytotoxicity and estrogenic/anti-estrogenic/androgenic/anti-androgenic activities respectively. However, 11 bottle nipples showed no cytotoxicity or hormonal activity. Overall, it is important to detect the toxicity of final products since FCSPs can contain complex chemical substances that result in biological toxicity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemical Research Methods
Juan J. Aristizabal-Henao, Dominick J. Lemas, Fmily K. Griffin, Kaylie Anne Costa, Camden Camacho, John A. Bowden
Summary: The number of metabolomics studies has increased significantly in recent years, with advancements in analyte separation techniques and databases playing a major role in this growth. Establishing baseline metabolomics data using complementary data acquisition strategies can help address challenges in comparing data across studies. This study provides valuable nontargeted metabolomics data for various human reference materials, highlighting significant differences between sample types and supporting the use of nontargeted strategies in global metabolomics.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2021)
Article
Food Science & Technology
Joana Moura, Cintia Ferreira-Pego, Ana Sofia Fernandes
Summary: This study investigated the preferences, safety perceptions, and usage practices of Portuguese consumers regarding Food Contact Materials (FCM) used for cooking and food storage. Results showed that safety was the most important factor when choosing cookware materials, although the criteria varied with age. Most respondents recognized the risk of food contamination through cookware. Stainless steel and glass were considered the safest materials for cooking, and glass and plastic were the most commonly used for food storage. Older individuals had better maintenance practices and knowledge about handling cookware. There was a general lack of knowledge about FCM symbols. This study highlights the need to provide reliable information to the public regarding cookware, promoting health literacy and reducing exposure to food contact chemicals.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Environmental Sciences
K. Bouma, D. K. Kalsbeek-van Wijk, D. T. H. M. Sijm
Summary: Bamboo/melamine cups, marketed as ecofriendly and sustainable, may release formaldehyde and melamine into beverages. A study by the Netherlands Food and Consumer Product Safety Authority found that some cups had high formaldehyde migration levels, posing health risks. Babies and young children are particularly vulnerable due to their lower body weight. As a result, some EU member states have banned these products from the market.
Article
Agriculture, Multidisciplinary
Ya-Li Bai, Cai-Feng Xiong, Xiaoming Yin, Tiantian Ye, Bao-Dong Cai, Wen-Li Song, Yu-Qi Feng
Summary: In this study, a screening strategy was established based on CIL-UPLC-HRMS for screening and identifying ABA catabolites. By proposing the structures of catabolites to be discovered and using chemical isotope labeling, ABA and its catabolites were successfully identified, including two previously unidentified catabolites.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Aparna Agarwal, Shivika Gandhi, Abhishek Dutt Tripathi, Marco Iammarino, Snigdha Homroy
Summary: This study analysed the migration of BPA in coffee from different qualities of polycarbonate microwaveable cups using UHPLC. The results showed that BPA migration was minimal in good-quality cups, but increased significantly in poor-quality cups with longer contact duration. The leaching process of BPA was enhanced during microwave heating due to high temperatures reached in a short time.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Birgit Geueke, Ksenia J. Groh, Maricel V. Maffini, Olwenn V. Martin, Justin M. Boucher, Yu-Ting Chiang, Frank Gwosdz, Phoenix Jieh, Christopher D. Kassotis, Paulina Lanska, John Peterson Myers, Alex Odermatt, Lindsey V. Parkinson, Verena N. Schreier, Vanessa Srebny, Lisa Zimmermann, Martin Scheringer, Jane Muncke
Summary: Food packaging plays a crucial role in today's globalized food system, but it can also contribute to the migration of hazardous chemicals into food. In order to assess the impact of food contact materials (FCMs) on human health, it is necessary to identify the chemicals they contain, known as food contact chemicals (FCCs). This study compiled a comprehensive database of migrating and extractable FCCs (FCCmigex) based on information from 1210 studies. The findings reveal that 2881 FCCs have been detected in six FCM groups, with 65% of these being previously unknown. Plastic, with 1975 detected FCCs, is the most extensively studied FCM. This knowledge expands our understanding of FCCs to 14,153 chemicals and can contribute to the development of non-hazardous FCMs, promoting safer food production and supporting a circular economy.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Emmanouil D. Tsochatzis, Natalia P. Vidal, Wenqiang Bai, Dimitra Diamantidou, Georgios Theodoridis, Mario M. Martinez
Summary: The chemical safety of representative polysaccharide films made with pea starch, organocatalytic acetylated pea starch, and pectin was investigated. Migration testing using different simulants showed the presence of certain compounds, such as glycerol, monoacetylated maltose, and dibutyl phthalate, in samples containing acetylated starch. In-silico toxicity assessment indicated no significant toxicity and categorized organocatalytic acetylated pea starch as safe.
Article
Biochemistry & Molecular Biology
Steve Thomas Pannakal, Joan Eilstein, Jane Hubert, Alexis Kotland, Arpita Prasad, Amelie Gueguiniat-Prevot, Franck Juchaux, Floriane Beaumard, Ganapaty Seru, Sherluck John, Dhimoy Roy
Summary: In this study, the aerial parts of the meadowsweet plant were extensively analyzed using NMR-based dereplication strategy, resulting in the identification of 28 compounds. It was found that certain components in the meadowsweet extract can enhance skin barrier function and promote skin renewal. This research has the potential to provide a natural solution for improving hydration and skin renewal properties.
Article
Food Science & Technology
Maurus Biedermann, Tanja Altherr, Sandra Biedermann-Brem, Angela Eicher, Celine Munoz, Gregor McCombie
Summary: A national follow-up was conducted in Switzerland on 109 samples a decade after larger pan European campaigns. The study focused on the compliance of migration of plasticizers from the gaskets for lids into oily food in glass jars. The results showed that the proportion of non-compliant samples was lower due to the use of non-PVC sealing plastics, but comparable to a decade ago for samples with a PVC-based sealant.
FOOD PACKAGING AND SHELF LIFE
(2022)
Review
Chemistry, Analytical
Guadalupe Garcia-Llatas, Amparo Alegria, Reyes Barbera, Antonio Cilla
Summary: Plant sterols are bioactive compounds found in all vegetable foods, with potential beneficial effects on lowering cholesterol levels. Analytical methods are needed to assess their health benefits and future applications. Current methodologies include extraction and analysis, with mass spectrometry widely used for its sensitivity and selectivity.
MICROCHEMICAL JOURNAL
(2021)
Review
Engineering, Environmental
Spyridoula Gerassimidou, Birgit Geueke, Ksenia J. Groh, Jane Muncke, John N. Hahladakis, Olwenn Martin, Eleni Iacovidou
Summary: Polyethylene (PE) is widely used in plastic food packaging, and this study explores the migration of food contact chemicals (FCCs) across the lifecycle of PE packaging. Out of 377 FCCs detected, 211 were found to migrate from PE articles into food. Only 25% of the detected FCCs are authorized for food contact materials by EU regulation, and a significant number of both authorized and non-authorized FCCs exceeded the migration limits. The evidence on FCCs migration across the PE packaging lifecycle is incomplete, especially at the reprocessing stage.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)