Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer’s disease: A tracer kinetic modeling study

Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging

(2020) David Matuskey et al.   ANNALS OF NEUROLOGY

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

(2020) Ellis Chika Onwordi et al.   Nature Communications

In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET

(2020) Adam P. Mecca et al.   Alzheimers & Dementia

Binding of the synaptic vesicle radiotracer [11C]UCB-J is unchanged during functional brain activation using a visual stimulation task

(2020) Kelly Smart et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Simplified Quantification of 11C-UCB-J PET Evaluated in a Large Human Cohort

(2020) Mika Naganawa et al.   JOURNAL OF NUCLEAR MEDICINE

Associations between vascular function and tau PET are associated with global cognition and amyloid

(2020) Daniel Albrecht et al.   JOURNAL OF NEUROSCIENCE

Assessment of population-based input functions for Patlak imaging of whole body dynamic 18F-FDG PET

(2020) Mika Naganawa et al.   EJNMMI Physics

Metabolic Plasticity of Astrocytes and Aging of the Brain

(2019) Mitsuhiro Morita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

(2019) Sjoerd J. Finnema et al.   EPILEPSIA

Lower synaptic density is associated with depression severity and network alterations

(2019) Sophie E. Holmes et al.   Nature Communications

Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease

(2019) Christopher H. van Dyck et al.   JAMA Neurology

The promise of fully-integrated PET/MR imaging: Non-invasive clinical quantification of cerebral glucose metabolism.

(2019) Lalith Kumar Shiyam Sundar et al.   JOURNAL OF NUCLEAR MEDICINE

An Exploratory Phase IIa Study of the PPAR delta/gamma Agonist T3D-959 Assessing Metabolic and Cognitive Function in Subjects with Mild to Moderate Alzheimer’s Disease

(2019) Stanley Chamberlain et al.   JOURNAL OF ALZHEIMERS DISEASE

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Relationships Between Tau and Glucose Metabolism Reflect Alzheimer’s Disease Pathology in Cognitively Normal Older Adults

(2018) Jenna N Adams et al.   CEREBRAL CORTEX

Clinical utility of FDG-PET for the clinical diagnosis in MCI

(2018) Javier Arbizu et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Clinical utility of FDG-PET for the differential diagnosis among the main forms of dementia

(2018) Peter J. Nestor et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease

(2018) Alexander Drzezga et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vivo characterization and quantification of neurofibrillary tau PET radioligand [18F]MK-6240 in humans from Alzheimer’s disease dementia to young controls

(2018) Tobey J Betthauser et al.   JOURNAL OF NUCLEAR MEDICINE

Cortical β-amyloid burden, gray matter, and memory in adults at varying APOE ε4 risk for Alzheimer's disease

(2018) Adam P. Mecca et al.   NEUROBIOLOGY OF AGING

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

(2018) Ming-Kai Chen et al.   JAMA Neurology

Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

(2017) Sjoerd J Finnema et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clinical Use and Utility of Amyloid Imaging

(2017) Henryk Barthel et al.   JOURNAL OF NUCLEAR MEDICINE

[18F]FDG PET signal is driven by astroglial glutamate transport

(2017) Eduardo R Zimmer et al.   NATURE NEUROSCIENCE

Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

(2016) Martijn C. de Wilde et al.   Alzheimers & Dementia

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

Comparison of Early-Phase 11C-Deuterium-L-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease

(2016) E. Rodriguez-Vieitez et al.   JOURNAL OF NUCLEAR MEDICINE

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

(2016) Clifford R. Jack et al.   NEUROLOGY

Cannabis Abusers Show Hypofrontality and Blunted Brain Responses to a Stimulant Challenge in Females but not in Males

(2016) Corinde E Wiers et al.   NEUROPSYCHOPHARMACOLOGY

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease

(2016) Gérard N. Bischof et al.   Annals of Clinical and Translational Neurology

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Relationship Between Alzheimer Disease-Like Pattern of 18F-FDG and Fasting Plasma Glucose Levels in Cognitively Normal Volunteers

(2015) K. Ishibashi et al.   JOURNAL OF NUCLEAR MEDICINE

Accurate automatic estimation of total intracranial volume: A nuisance variable with less nuisance

(2015) Ian B. Malone et al.   NEUROIMAGE

Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and18F-FDG PET Quantitative Analysis Using FreeSurfer

(2015) Matthieu Bailly et al.   Biomed Research International

Diaschisis: past, present, future

(2014) Emmanuel Carrera et al.   BRAIN

Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions

(2013) C. M. Burns et al.   NEUROLOGY

A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology

(2012) Kjell Erlandsson et al.   PHYSICS IN MEDICINE AND BIOLOGY

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

(2011) Mario Merlini et al.   ACTA NEUROPATHOLOGICA

Functional implications of hippocampal degeneration in early Alzheimer’s disease: a combined DTI and PET study

(2011) Igor Yakushev et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Protein Quantification at the Single Vesicle Level Reveals That a Subset of Synaptic Vesicle Proteins Are Trafficked with High Precision

(2011) S. A. Mutch et al.   JOURNAL OF NEUROSCIENCE

Dual-Biomarker Imaging of Regional Cerebral Amyloid Load and Neuronal Activity in Dementia with PET and 11C-Labeled Pittsburgh Compound B

(2011) P. T. Meyer et al.   JOURNAL OF NUCLEAR MEDICINE

Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease

(2011) Y. Chen et al.   NEUROLOGY

Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease

(2010) Ahmadul Kadir et al.   NEUROBIOLOGY OF AGING

Brain fuel metabolism, aging, and Alzheimer’s disease

(2010) Stephen Cunnane et al.   NUTRITION

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI

(2009) Susan M. Landau et al.   NEUROBIOLOGY OF AGING

Relationships between Hippocampal Atrophy, White Matter Disruption, and Gray Matter Hypometabolism in Alzheimer's Disease

(2008) N. Villain et al.   JOURNAL OF NEUROSCIENCE