Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process

Mitophagy during development and stress in C. elegans

(2020) Romane Leboutet et al.   MECHANISMS OF AGEING AND DEVELOPMENT

GFP fluorescence tagging alters dynamin-related protein 1 oligomerization dynamics and creates disassembly-refractory puncta to mediate mitochondrial fission

(2020) Felipe Montecinos-Franjola et al.   Scientific Reports

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

(2018) Arnaud Ahier et al.   NATURE CELL BIOLOGY

DRP-1-mediated apoptosis induces muscle degeneration in dystrophin mutants

(2018) Charlotte Scholtes et al.   Scientific Reports

Autophagy mediates phosphatidylserine exposure and phagosome degradation during apoptosis through specific functions of GABARAP/LGG-1 and LC3/LGG-2

(2018) Céline Jenzer et al.   Autophagy

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Drp1-Zip1 Interaction Regulates Mitochondrial Quality Surveillance System

(2018) Hyo Min Cho et al.   MOLECULAR CELL

Heat-Induced Calcium Leakage Causes Mitochondrial Damage inCaenorhabditis elegansBody-Wall Muscles

(2017) Kenta Momma et al.   GENETICS

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

The constriction and scission machineries involved in mitochondrial fission

(2017) Felix Kraus et al.   JOURNAL OF CELL SCIENCE

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

(2017) Yan G. Zhao et al.   MOLECULAR CELL

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caenorhabditis elegans ATPase inhibitor factor 1 (IF1) MAI-2 preserves the mitochondrial membrane potential (Δψm) and is important to induce germ cell apoptosis

(2017) L. P. Fernández-Cárdenas et al.   PLoS One

Temporal dynamics of gene expression in heat-stressed Caenorhabditis elegans

(2017) Katharina Jovic et al.   PLoS One

Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans

(2017) Caroline Kumsta et al.   Nature Communications

Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging

(2017) Johnathan Labbadia et al.   Cell Reports

Heat-Induced Calcium Leakage Causes Mitochondrial Damage inCaenorhabditis elegansBody-Wall Muscles

(2017) Kenta Momma et al.   GENETICS

Approaches for Studying Autophagy in Caenorhabditis elegans

(2017) Yanfang Chen et al.   Cells

Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

(2016) Shun-ichi Yamashita et al.   JOURNAL OF CELL BIOLOGY

Multiple dynamin family members collaborate to drive mitochondrial division

(2016) Jason E. Lee et al.   NATURE

A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans

(2016) Mandy Koopman et al.   Nature Protocols

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

(2016) Q. Zhou et al.   SCIENCE

Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans

(2016) Yang Wang et al.   Nature Communications

Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells

(2015) K. D. Elgass et al.   JOURNAL OF CELL SCIENCE

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes

(2015) Anthony L. Luz et al.   PLoS One

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

High-Throughput Cloning of Temperature-Sensitive Caenorhabditis elegans Mutants with Adult Syncytial Germline Membrane Architecture Defects

(2015) Josh Lowry et al.   G3-Genes Genomes Genetics

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

(2015) Wei-ke Ji et al.   eLife

Human GABARAP can restore autophagosome biogenesis in aC. elegans lgg-1mutant

(2014) Céline Jenzer et al.   Autophagy

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

The C. elegans LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39

(2014) Marion Manil-Ségalen et al.   DEVELOPMENTAL CELL

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

Methodological considerations for heat shock of the nematode Caenorhabditis elegans

(2014) Shannin C. Zevian et al.   METHODS

Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)

(2013) Shruti Desai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory Coordination between Two Major Intracellular Homeostatic Systems

(2013) Karol Dokladny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

(2013) Qinfang Shen et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond

(2013) Cole M. Haynes et al.   TRENDS IN CELL BIOLOGY

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2

(2011) N. Mendl et al.   JOURNAL OF CELL SCIENCE

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

(2011) M. Sato et al.   SCIENCE

Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission

(2011) S. Al Rawi et al.   SCIENCE

The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans

(2010) Adriana Alberti et al.   Autophagy

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9

(2008) David G. Breckenridge et al.   MOLECULAR CELL