Photobiomodulation Therapy for Dementia: A Systematic Review of Pre-Clinical and Clinical Studies

Blood contains circulating cell‐free respiratory competent mitochondria

(2020) Zahra Al Amir Dache et al.   FASEB JOURNAL

Photobiomodulation for Parkinson’s Disease in Animal Models: A Systematic Review

(2020) Farzad Salehpour et al.   Biomolecules

Time courses of BOLD responses during transcranial near-infrared laser irradiation

(2019) Hiroshi Nawashiro et al.   Brain Stimulation

Selective photobiomodulation for emotion regulation: model-based dosimetry study

(2019) Paolo Cassano et al.   Neurophotonics

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer’s disease

(2019) Ekaterina Zinchenko et al.   Biomedical Optics Express

Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study

(2019) Reza Zomorrodi et al.   Scientific Reports

Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review

(2019) Farzad Salehpour et al.   REVIEWS IN THE NEUROSCIENCES

Illumination with 630-nm red light reduces oxidative stress and restores memory by photo-activating catalase and formaldehyde dehydrogenase in SAMP8 mice

(2018) Jingnan Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain Photobiomodulation Therapy: a Narrative Review

(2018) Farzad Salehpour et al.   MOLECULAR NEUROBIOLOGY

Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation

(2018) Michael R. Hamblin   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Photobiomodulation using low-level laser therapy (LLLT) for patients with chronic traumatic brain injury: a randomized controlled trial study protocol

(2018) Guilherme da Cruz Ribeiro Poiani et al.   Trials

Near infra-red light treatment of Alzheimer’s disease

(2018) Mengmeng Han et al.   Journal of Innovative Optical Health Sciences

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Transcranial Laser Therapy Attenuates Amyloid-β Peptide Neuropathology in Amyloid-β Protein Precursor Transgenic Mice

(2018) Luis De Taboada et al.   JOURNAL OF ALZHEIMERS DISEASE

Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies

(2018) Michele M. Comerota et al.   MOLECULAR NEUROBIOLOGY

Low-level light therapy reduces platelet destruction during extracorporeal circulation

(2018) Anna Drohomirecka et al.   Scientific Reports

Photobiomodulation for traumatic brain injury and stroke

(2017) Michael R. Hamblin   JOURNAL OF NEUROSCIENCE RESEARCH

Transcranial LED therapy on amyloid-β toxin 25–35 in the hippocampal region of rats

(2017) Camila da Luz Eltchechem et al.   LASERS IN MEDICAL SCIENCE

Low-level laser therapy for beta amyloid toxicity in rat hippocampus

(2017) Yujiao Lu et al.   NEUROBIOLOGY OF AGING

Low-Level Laser Irradiation Exerts Antiaggregative Effect on Human Platelets Independently on the Nitric Oxide Metabolism and Release of Platelet Activation Markers

(2017) Piotr Rola et al.   Oxidative Medicine and Cellular Longevity

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers

(2017) Michele M. Comerota et al.   Scientific Reports

Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy

(2016) Lucas Freitas de Freitas et al.   IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

Noninvasive low-level laser therapy for thrombocytopenia

(2016) Qi Zhang et al.   Science Translational Medicine

Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia

(2016) Rosebud O. Roberts et al.   JAMA Neurology

Low-level light treatment ameliorates immune thrombocytopenia

(2016) Jingke Yang et al.   Scientific Reports

Neurobiology of Alzheimer’s Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions

(2015) Joel Raskin et al.   Current Alzheimer Research

Near infrared light mitigates cerebellar pathology in transgenic mouse models of dementia

(2015) Sivaraman Purushothuman et al.   NEUROSCIENCE LETTERS

Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice

(2014) Weijun Xuan et al.   JOURNAL OF BIOMEDICAL OPTICS

Low-level laser therapy for traumatic brain injury in mice increases brain derived neurotrophic factor (BDNF) and synaptogenesis

(2014) Weijun Xuan et al.   Journal of Biophotonics

Low-Level Laser Therapy Ameliorates Disease Progression in a Mouse Model of Alzheimer’s Disease

(2014) Dorit Farfara et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Photobiomodulation with near infrared light mitigates Alzheimer’s disease-related pathology in cerebral cortex – evidence from two transgenic mouse models

(2014) Sivaraman Purushothuman et al.   Alzheimers Research & Therapy

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Low-level laser therapy (810 nm) protects primary cortical neurons against excitotoxicity in vitro

(2013) Ying-Ying Huang et al.   Journal of Biophotonics

Low-Level Laser Therapy Rescues Dendrite Atrophy via Upregulating BDNF Expression: Implications for Alzheimer's Disease

(2013) C. Meng et al.   JOURNAL OF NEUROSCIENCE

Non-invasive infra-red therapy (1072nm) reduces β-amyloid protein levels in the brain of an Alzheimer’s disease mouse model, TASTPM

(2013) S.L. Grillo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Nanoparticle-emitted light attenuates amyloid-β-induced superoxide and inflammation in astrocytes

(2013) Brittani L. Bungart et al.   Nanomedicine-Nanotechnology Biology and Medicine

Neuroimaging in Alzheimer's disease: current role in clinical practice and potential future applications

(2012) Luiz Kobuti Ferreira et al.   Clinics

Photobiomodulation by low-power laser irradiation attenuates Aβ-induced cell apoptosis through the Akt/GSK3β/β-catenin pathway

(2012) Jiangang Liang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of Intranetwork and Internetwork Resting State Functional Connections with Alzheimer's Disease Progression

(2012) M. R. Brier et al.   JOURNAL OF NEUROSCIENCE

Neuropsychiatric symptoms in Alzheimer’s disease

(2011) Constantine G. Lyketsos et al.   Alzheimers & Dementia

The Nuts and Bolts of Low-level Laser (Light) Therapy

(2011) Hoon Chung et al.   ANNALS OF BIOMEDICAL ENGINEERING

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

(2011) H. Rheinallt Parri et al.   BIOCHEMICAL PHARMACOLOGY

Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

(2011) P. Hemachandra Reddy   BRAIN RESEARCH

Inhibition of Aβ25–35-induced cell apoptosis by Low-power-laser-irradiation (LPLI) through promoting Akt-dependent YAP cytoplasmic translocation

(2011) Heng Zhang et al.   CELLULAR SIGNALLING

Relationships between Beta-Amyloid and Functional Connectivity in Different Components of the Default Mode Network in Aging

(2011) Elizabeth C. Mormino et al.   CEREBRAL CORTEX

Transcranial near-infrared laser therapy applied to promote clinical recovery in acute and chronic neurodegenerative diseases

(2011) Paul A Lapchak   Expert Review of Medical Devices

670 nm Laser Light and EGCG Complementarily Reduce Amyloid-β Aggregates in Human Neuroblastoma Cells: Basis for Treatment of Alzheimer's Disease?

(2011) Andrei P. Sommer et al.   PHOTOMEDICINE AND LASER SURGERY

Low energy laser light (632.8 nm) suppresses amyloid-β peptide-induced oxidative and inflammatory responses in astrocytes

(2010) X. Yang et al.   NEUROSCIENCE

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety

(2009) Fredric Schiffer et al.   Behavioral and Brain Functions

Low infra red laser light irradiation on cultured neural cells: effects on mitochondria and cell viability after oxidative stress

(2009) Alessandro Giuliani et al.   BMC Complementary and Alternative Medicine

Inhibition of mitochondria-dependent apoptosis by 635-nm irradiation in sodium nitroprusside-treated SH-SY5Y cells

(2009) WonBong Lim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Attention and working memory deficits in mild cognitive impairment

(2009) Nichole L. J. Saunders et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

Insight, cognition and quality of life in Alzheimer's disease

(2009) C. Hurt et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Disruption of Functional Connectivity in Clinically Normal Older Adults Harboring Amyloid Burden

(2009) T. Hedden et al.   JOURNAL OF NEUROSCIENCE

Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials

(2009) Roberta T Chow et al.   LANCET

Mild Cognitive Impairment and Alzheimer Disease: Patterns of Altered Cerebral Blood Flow at MR Imaging

(2009) Weiying Dai et al.   RADIOLOGY

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity

(2008) Rong Ying et al.   BRAIN RESEARCH

Low-Power Laser Irradiation Inhibiting Aβ25-35-induced PC12 Cell Apoptosis via PKC Activation

(2008) Lan Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effects of ageing and Alzheimer’s disease on mitochondrial function of human platelets

(2008) Chun Shi et al.   EXPERIMENTAL GERONTOLOGY

Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity

(2008) H.L. Liang et al.   NEUROSCIENCE