Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways

Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome

(2020) Jeanette N. McClintick et al.   ALCOHOL

Luteolin alleviates ochratoxin A induced oxidative stress by regulating Nrf2 and HIF-1α pathways in NRK-52E rat kidney cells

(2020) Man Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulatory effects of Ganoderma atrum polysaccharides on LPS-induced inflammatory macrophages model and intestinal-like Caco-2/macrophages co-culture inflammation model

(2020) Xiaoyi Hu et al.   FOOD AND CHEMICAL TOXICOLOGY

Luteolin suppresses IL-31 production in IL-33-stimulated mast cells through MAPK and NF-κB signaling pathways

(2020) Denis Nchang Che et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Puerarin Rebuilding the Mucus Layer and Regulating Mucin-Utilizing Bacteria to Relieve Ulcerative Colitis

(2020) Yi Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Puerarin prevents epithelial tight junction dysfunction induced by ethanol in Caco-2 cell model

(2020) Si-yan Che et al.   Journal of Functional Foods

Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

(2019) Kyoung Ah Kang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Melatonin Prevents Mice Cortical Astrocytes From Hemin-Induced Toxicity Through Activating PKCα/Nrf2/HO-1 Signaling in vitro

(2019) Xiao Chen et al.   Frontiers in Neuroscience

Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis

(2019) Eleonora Cremonini et al.   Redox Biology

Naringin attenuates MLC phosphorylation and NF-κB activation to protect sepsis-induced intestinal injury via RhoA/ROCK pathway

(2018) Zhiling Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Attenuation of tert-Butyl Hydroperoxide (t-BHP)-Induced Oxidative Damage in HepG2 Cells by Tangeretin: Relevance of the Nrf2–ARE and MAPK Signaling Pathways

(2018) Fuqiang Liang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Flavonoids and the gastrointestinal tract: Local and systemic effects

(2018) P.I. Oteiza et al.   MOLECULAR ASPECTS OF MEDICINE

Intestinal barriers protect against disease

(2018) Sandra Citi   SCIENCE

Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling pathway in mice

(2018) Hongli Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alcoholism: A Multi-Systemic Cellular Insult to Organs

(2018) Ucee Dguzeh et al.   International Journal of Environmental Research and Public Health

An HPLC-MS/MS method for the simultaneous determination of luteolin and its major metabolites in rat plasma and its application to a pharmacokinetic study

(2018) Fuguo Shi et al.   JOURNAL OF SEPARATION SCIENCE

Isoliquiritigenin Protects Against Pancreatic Injury and Intestinal Dysfunction After Severe Acute Pancreatitis via Nrf2 Signaling

(2018) Man Zhang et al.   Frontiers in Pharmacology

Absorption and Metabolism of Luteolin in Rats and Humans in Relation to in Vitro Anti-inflammatory Effects

(2018) Natsumi Hayasaka et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous Determination and Pharmacokinetic Study of Quercetin, Luteolin, and Apigenin in Rat Plasma after Oral Administration of Matricaria chamomilla L. Extract by HPLC-UV

(2017) Xiaoxv Dong et al.   Evidence-based Complementary and Alternative Medicine

Flavonoid composition of orange peel extract ameliorates alcohol-induced tight junction dysfunction in Caco-2 monolayer

(2017) Xiu-Min Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in rat

(2017) Slimen Selmi et al.   Lipids in Health and Disease

Semipurified Ethyl Acetate Partition of Methanolic Extract ofMelastoma malabathricumLeaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds

(2017) Noor Wahida Ismail Suhaimy et al.   Oxidative Medicine and Cellular Longevity

Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review

(2017) Ali Salaritabar et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Ethanol concentrations in the human gastrointestinal tract after intake of alcoholic beverages

(2016) Jari Rubbens et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Luteolin ameliorates dextran sulfate sodium-induced colitis in mice possibly through activation of the Nrf2 signaling pathway

(2016) Yue Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect

(2016) Ayako Kure et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Role of miR-212 and iNOS in Alcohol-Induced Intestinal Barrier Dysfunction and Steatohepatitis

(2015) Yueming Tang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Cystic Fibrosis-Related Oxidative Stress and Intestinal Lipid Disorders

(2015) Marie-Laure Kleme et al.   ANTIOXIDANTS & REDOX SIGNALING

Ethanol Impairs Intestinal Barrier Function in Humans through Mitogen Activated Protein Kinase Signaling: A Combined In Vivo and In Vitro Approach

(2014) Elhaseen Elamin et al.   PLoS One

Regulation of intestinal epithelial permeability by tight junctions

(2012) Takuya Suzuki   CELLULAR AND MOLECULAR LIFE SCIENCES

Correlation among Antioxidant, Antimicrobial, Hemolytic, and Antiproliferative Properties of Leiothrix spiralis Leaves Extract

(2012) Marcelo Gonzaga de Freitas Araújo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells

(2012) Xiaohan Zhai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats

(2008) Ali Keshavarzian et al.   JOURNAL OF HEPATOLOGY

Molecular mechanisms of natural products in chemoprevention: Induction of cytoprotective enzymes by Nrf2

(2008) Aimee L. Eggler et al.   MOLECULAR NUTRITION & FOOD RESEARCH