A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications

Engineered β-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregates

(2020) Concetta Di Natale et al.   BIOORGANIC CHEMISTRY

Metal complexes that bind to the amyloid-β peptide of relevance to Alzheimer’s disease

(2020) Luiza M.F. Gomes et al.   COORDINATION CHEMISTRY REVIEWS

Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes

(2020) Daniele Florio et al.   Pharmaceuticals

Proteostasis unbalance of nucleophosmin 1 in Acute Myeloid Leukemia: An aggregomic perspective

(2020) Concetta Di Natale et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Non-conventional photoactive transition metal complexes that mediated sensing and inhibition of amyloidogenic aggregates

(2020) Eththilu Babu et al.   COORDINATION CHEMISTRY REVIEWS

Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems

(2019) Daniele Florio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Acute Myeloid Leukemia‐associated Nucleophosmin 1 gene mutations dictate amyloidogenicity of the C‐terminal domain

(2019) Sara La Manna et al.   FEBS Journal

Structural insights into amyloid structures of the C-terminal region of nucleophosmin 1 in type A mutation of acute myeloid leukemia

(2019) Concetta Di Natale et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Transition Metal Ion Interactions with Disordered Amyloid-β Peptides in the Pathogenesis of Alzheimer’s Disease: Insights from Computational Chemistry Studies

(2019) Birgit Strodel et al.   Journal of Chemical Information and Modeling

Amyloid Protein-Induced Supramolecular Self-Assembly of Water-Soluble Platinum(II) Complexes: A Luminescence Assay for Amyloid Fibrillation Detection and Inhibitor Screening

(2019) Angela Sin-Yee Law et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes

(2019) Luiza M. F. Gomes et al.   Frontiers in Chemistry

Stabilization and characterization of cytotoxic Aβ40 oligomers isolated from an aggregation reaction in the presence of zinc ions

(2018) Benedetta Mannini et al.   ACS Chemical Neuroscience

Light-triggered dissociation of self-assembled β-amyloid aggregates into small, nontoxic fragments by ruthenium (II) complex

(2018) Giyeong Son et al.   Acta Biomaterialia

Nucleophosmin-1 regions associated with acute myeloid leukemia interact differently with lipid membranes

(2018) Augusta De Santis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Strategies Employing Transition Metal Complexes To Modulate Amyloid-β Aggregation

(2018) Jong-Min Suh et al.   INORGANIC CHEMISTRY

Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-β Peptides

(2017) Jeffrey S. Derrick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondria Targeting with Luminescent Rhenium(I) Complexes

(2017) Joanna Skiba et al.   MOLECULES

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia

(2016) Pasqualina Liana Scognamiglio et al.   Oncotarget

A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration

(2016) Karen E. Marshall et al.   Scientific Reports

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions

(2015) Concetta Di Natale et al.   FASEB JOURNAL

Application of microwave-assisted heating to the synthesis of Pt(II) complexes

(2015) Elisabetta Gabano et al.   INORGANICA CHIMICA ACTA

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metallodrugs in Medicinal Inorganic Chemistry

(2014) Katja Dralle Mjos et al.   CHEMICAL REVIEWS

Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease

(2014) David J. Hayne et al.   CHEMICAL SOCIETY REVIEWS

Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide

(2013) Victor A. Streltsov et al.   CHEMICAL COMMUNICATIONS

Pt(ii) compounds interplay with Cu(ii) and Zn(ii) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease

(2013) Fabrice Collin et al.   CHEMICAL COMMUNICATIONS

PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide

(2013) Guolin Ma et al.   Metallomics

Interference of a new cyclometallated Pt compound with Cu binding to amyloid-β peptide

(2012) Isabelle Sasaki et al.   DALTON TRANSACTIONS

Inhibitory action of macrocyclic platiniferous chelators on metal-induced Aβ aggregation

(2012) Xiaohui Wang et al.   Chemical Science

New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries

(2011) Nunzianna Doti et al.   BIOCHEMICAL JOURNAL

Identification of [PtCl2(phen)] Binding Modes in Amyloid-β Peptide and the Mechanism of Aggregation Inhibition

(2011) Guolin Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells

(2007) A M Malfitano et al.   BRITISH JOURNAL OF PHARMACOLOGY