Intravitreal Injection of an Exosome-Associated Adeno-Associated Viral Vector Enhances Retinoschisin 1 Gene Transduction in the Mouse Retina

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Extracellular vesicles as drug delivery systems: Why and how?

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Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina

(2019) J. Bernard Heymann et al.   JOURNAL OF CELL BIOLOGY

Drug Delivery with Extracellular Vesicles: From Imagination to Innovation

(2019) Olivier G. de Jong et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mouse models of X-linked juvenile retinoschisis have an early onset phenotype, the severity of which varies with genotype

(2019) Yang Liu et al.   HUMAN MOLECULAR GENETICS

Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

(2019) Nicola Salvatore Orefice et al.   Molecular Therapy-Methods & Clinical Development

Retinal AAV8- RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery

(2018) Catherine Cukras et al.   MOLECULAR THERAPY

Exosomes in Myocardial Repair: Advances and Challenges in the Development of Next-Generation Therapeutics

(2018) Marta Adamiak et al.   MOLECULAR THERAPY

Effects of mesenchymal stem cells and their exosomes on the healing of large and refractory macular holes

(2018) Xiaomin Zhang et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye

(2017) Li Wang et al.   PLoS One

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

(2017) Sarah J. Wassmer et al.   Scientific Reports

Erratum: Exosome-associated AAV vector as a robust and convenient neuroscience tool

(2016) E Hudry et al.   GENE THERAPY

An essential receptor for adeno-associated virus infection

(2016) S. Pillay et al.   NATURE

Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice

(2016) Dario Marangoni et al.   Molecular Therapy-Methods & Clinical Development

Cog-Wheel Octameric Structure of RS1, the Discoidin Domain Containing Retinal Protein Associated with X-Linked Retinoschisis

(2016) Martin Bush et al.   PLoS One

AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways

(2016) Yiguo Qiu et al.   Scientific Reports

Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions

(2015) Bence György et al.   Annual Review of Pharmacology and Toxicology

Safety and Biodistribution Evaluation of rAAV2tYF-CB-hRS1, a Recombinant Adeno-Associated Virus Vector Expressing Retinoschisin, in RS1-Deficient Mice

(2015) Guo-Jie Ye et al.   Human Gene Therapy Clinical Development

Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo

(2014) Bence György et al.   BIOMATERIALS

Exosomes for targeted siRNA delivery across biological barriers

(2012) Samir EL Andaloussi et al.   ADVANCED DRUG DELIVERY REVIEWS

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

(2012) Casey A Maguire et al.   MOLECULAR THERAPY

Molecular analysis of the XLRS1 gene in 4 females affected with X-linked juvenile retinoschisis

(2008) Danish Saleheen et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE