Article
Medicine, General & Internal
Na Xu, Lin Jiang, Yi Yao, Jingjing Xu, Ru Liu, Huanhuan Wang, Ying Song, Lijian Gao, Zhan Gao, Xueyan Zhao, Bo Xu, Yaling Han, Jinqing Yuan
Summary: This study compares the clinical outcomes of using biodegradable polymer drug-eluting stents (BP-DES) and durable polymer drug-eluting stents (DP-DES) in complex percutaneous coronary intervention (CPCI). The results show that both CPCI and non-CPCI patients have a risk of adverse events in the mid- to long-term, and the effects of BP-DES and DP-DES differ in CPCI patients.
CHINESE MEDICAL JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Talha Ahmed, Homam Moussa Pacha, Antoine Addoumieh, Efstratios Koutroumpakis, Juhee Song, Konstantinos Charitakis, Konstantinos Dean Boudoulas, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, Cindy Grines, Cezar A. Iliescu
Summary: This study compared the outcomes of percutaneous coronary intervention (PCI) using bare metal stents (BMS) vs. drug-eluting stents (DES) in cancer patients. The results showed that there were similar rates of revascularizations and survival between the BMS and DES groups.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Medicine, General & Internal
Pierre Brami, Quentin Fischer, Vincent Pham, Gabriel Seret, Olivier Varenne, Fabien Picard
Summary: This article aims to provide a brief historical overview of the evolution of coronary DES platforms and an update on clinical studies and major characteristics of the most currently used DESs.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Rafael Romaguera, Pablo Salinas, Josep Gomez-Lara, Salvatore Brugaletta, Antonio Gomez-Menchero, Miguel A. Romero, Sergio Garcia-Blas, Raymundo Ocaranza, Pascual Bordes, Marcelo Jimenez Kockar, Neus Salvatella, Victor A. Jimenez-Diaz, Mar Alameda, Ramiro Trillo, Dae Hyun Lee, Pedro Martin, Maria Lopez-Benito, Alfonso Freites, Virginia Pascual-Tejerina, Felipe Hernandez-Hernandez, Bruno Garcia Del Blanco, Mohsen Mohandes, Francisco Bosa, Eduardo Pinar, Gerard Roura, Josep Comin-Colet, Antonio Fernandez-Ortiz, Carlos Macaya, Xavier Rossello, Manel Sabate, Stuart J. Pocock, Joan A. Gomez-Hospital
Summary: In a randomized controlled trial in Spain, researchers compared the Cre8 EVO stent with the Resolute Onyx stent in patients with diabetes undergoing percutaneous coronary intervention. The study found that the Cre8 EVO stent was non-inferior to the Resolute Onyx stent in terms of target-lesion failure composite outcome, with a suggestion of potential superiority for the Cre8 EVO stent at 1 year follow-up.
EUROPEAN HEART JOURNAL
(2022)
Article
Polymer Science
Yihui Jian, Yufang Zhu
Summary: In this study, the biodegradable polymer P34HB was proposed as a coating material for drug-eluting stents. P34HB exhibited excellent solubility and stability in drug solutions, as well as good adhesion and resistance properties. It showed better drug release control compared to other candidates and is suitable for latent coating polymer of coronary stents.
Article
Cardiac & Cardiovascular Systems
J. J. Coughlan, Lorenz Raber, Salvatore Brugaletta, Sebastian Kufner, Michael Maeng, Lisette Okkels Jensen, Luis Ortega-Paz, Sarah Bar, Karl-Ludwig Laugwitz, Morten Madsen, Dik Heg, Alp Aytekin, Stephan Windecker, Kevin Kris Warnakula Olesen, Manel Sabate, Adnan Kastrati, Salvatore Cassese
Summary: This study analyzed the long-term follow-up outcomes of patients receiving drug-eluting stent (DES) implantation and found that female patients have an increased risk of early myocardial infarction but no difference in cardiovascular mortality compared with male patients. Additionally, female patients require fewer repeat revascularizations during the follow-up period.
Article
Polymer Science
Yihui Jian, Yufang Zhu
Summary: Drug-eluting stents (DES) are the main method of intervention for coronary heart disease, and their drug coating can effectively reduce the incidence of restenosis. In this study, the biodegradable polymer P34HB was used as a coating on stents, showing slower and sustained drug release rates compared to Firebird2.
Article
Peripheral Vascular Disease
Wei-Ting Chang, Sudeshna Fisch, Seema Dangwal, Michael Chen, Susan Cheng, Zhih-Cherng Chen, Ronglih Liao
Summary: Coronary flow velocity is decreased in pathologic cardiac hypertrophy, linked to angiotensin II. Angiotensin receptor blockers have been shown to improve CFV and cardiac function. This suggests a molecular and functional link between angiotensin-induced hemodynamic remodeling and coronary vasculature changes.
HYPERTENSION RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Alexandra J. Lansky, Dean J. Kereiakes, Andreas Baumbach, Stephan Windecker, Yasin Hussain, Cody Pietras, Ovidiu Dressler, Ozgu Issever, Michael Curtis, Barry Bertolet, James P. Zidar, Pieter C. Smits, Victor Alfonso Jimenez Diaz, Brent McLaurin, Sjoerd Hofma, Angel Cequier, Nabil Dib, Edouard Benit, Anthony Mathur, David Brogno, Jacques Berland, Joanna Wykrzykowska, Guy Piegari, Salvatore Brugaletta, Shigeru Saito, Martin B. Leon
Summary: Among patients with acute and chronic coronary syndromes undergoing percutaneous coronary intervention, the Supreme DES proved to be noninferior to the standard DP-EES.
Article
Clinical Neurology
Jonne Lintunen, Markku Lahteenvuo, Antti Tanskanen, Jari Tiihonen, Heidi Taipale
Summary: This study found that the use of calcium-channel blockers and adenosine modulators is associated with a decreased risk of hospitalization in patients with bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Yunpeng Bai, Yiming Bai, Nan Jiang, Qingliang Chen, Zhigang Guo
Summary: This article reports a case of perioperative coronary artery spasm (CAS) following off-pump CABG in the non-manipulated coronary artery, highlighting the importance of this condition in clinical practice.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Hyo-Soo Kim, Jeehoon Kang, Doyeon Hwang, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo, Seok Yeon Kim, Keun-Ho Park, Seung-Woon Rha, Won-Yong Shin, Hong-Seok Lim, Kyungil Park, Kyung Woo Park
Summary: The study demonstrated that in patients with acute coronary syndrome (ACS), durable polymer drug-eluting stents (DP-DES) were noninferior to biodegradable polymer DES (BP-DES) in terms of patient-oriented composite outcomes at 12 months after percutaneous coronary intervention.
Article
Pharmacology & Pharmacy
Liqiong Ding, Ping Jiang, Xinfeng Xu, Wanzhen Lu, Chan Yang, Lin Li, Pingzheng Zhou, Shuwen Liu
Summary: The study identified T-type calcium channel blockers as potential inhibitors of HSV-2 infection, while L-type calcium channel blockers showed no significant effect. Additionally, benidipine exerted antiviral effects by suppressing viral gene expression in the late stage of infection.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Michael I. Okereke, Roxanne Khalaj, Atabak Ghanizadeh Tabriz, Uttom Nandi, Nick Scoutaris, Dennis Douroumis
Summary: This study used computational modeling to investigate and predict the behavior of 3D printed stents. Racetrack-cell and diamond-cell shaped stents were printed using Fusion Deposition Modeling (FDM) with bioresorbable polymers. The study revealed that racetrack designs are marginally better than the diamond stent designs.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Josep Gomez-Lara, Loreto Oyarzabal, Luis Ortega-Paz, Salvatore Brugaletta, Rafael Romaguera, Neus Salvatella, Gerard Roura, Fernando Rivero, Lara Fuentes, Fernando Alfonso, Imanol Otaegui, Bert Vandeloo, Beatriz Vaquerizo, Manel Sabate, Josep Comin-Colet, Joan-Antoni Gomez-Hospital
Summary: This study investigated the impact of different stents on endothelial function, finding variations in vasomotor responses and neointimal healing between devices, but no significant differences in endothelial dysfunction issues.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Masanori Kanazawa, Yasuharu Matsumoto, Kikuyo Takahashi, Hideaki Suzuki, Hironori Uzuka, Kensuke Nishimiya, Hiroaki Shimokawa
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Takahiko Chiba, Makoto Nakano, Yuhi Hasebe, Yoshitaka Kimura, Kyoshiro Fukasawa, Keita Miki, Susumu Morosawa, Kentaro Takanami, Hideki Ota, Koji Fukuda, Hiroaki Shimokawa
JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Masateru Kondo, Koji Fukuda, Yuji Wakayama, Makoto Nakano, Yuhi Hasebe, Hiroyuki Satake, Masato Segawa, Michinori Hirano, Hiroaki Shimokawa
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2020)
Article
Respiratory System
Mina Akizuki, Koichiro Sugimura, Tatsuo Aoki, Takaaki Kakihana, Shunsuke Tatebe, Saori Yamamoto, Haruka Sato, Kmio Satoh, Hiroaki Shimokawa, Masahiro Kohzuki
Article
Cardiac & Cardiovascular Systems
Takashi Shiroto, Yasuhiko Sakata, Kotaro Nochioka, Ruri Abe, Shintaro Kasahara, Masayuki Sato, Hajime Aoyanagi, Takahide Fujihashi, Shinsuke Yamanaka, Hideka Hayashi, Masanobu Miura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Soichiro Tadaki, Yasuhiko Sakata, Yutaka Miura, Kotaro Nochioka, Masanobu Miura, Satoshi Miyata, Masanori Asakura, Kazunori Shimada, Takeshi Yamamoto, Yoshihiro Fukumoto, Toshiaki Kadokami, Satoshi Yasuda, Toshiro Miura, Shin-ichi Ando, Masafumi Yano, Masafumi Kitakaze, Hiroyuki Daida, Hiroaki Shimokawa
Article
Cardiac & Cardiovascular Systems
Katsuya Kozu, Koichiro Sugimura, Masaaki Ito, Ken-ichi Hirata, Koichi Node, Takuya Miyamoto, Shuichi Ueno, Hiroshi Watanabe, Hiroaki Shimokawa
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Hironari Nishizawa, Mitsuyo Matsumoto, Tomohiko Shindo, Daisuke Saigusa, Hiroki Kato, Katsushi Suzuki, Masaki Sato, Yusho Ishii, Hiroaki Shimokawa, Kazuhiko Igarashi
JOURNAL OF BIOLOGICAL CHEMISTRY
(2020)
Article
Cardiac & Cardiovascular Systems
Katsuya Kozu, Kimio Satoh, Tatsuo Aoki, Shunsuke Tatebe, Masanobu Miura, Saori Yamamoto, Nobuhiro Yaoita, Hideaki Suzuki, Toru Shimizu, Haruka Sato, Ryo Konno, Yosuke Terui, Kotaro Nochioka, Nobuhiro Kikuchi, Taijyu Satoh, Koichiro Sugimura, Satoshi Miyata, Hiroaki Shimokawa
JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Koichi Sato, Jun Takahashi, Kiyotaka Hao, Satoshi Miyata, Akira Suda, Tomohiko Shindo, Shohei Ikeda, Yoku Kikuchi, Takashi Shiroto, Yasuharu Matsumoto, Yasuhiko Sakata, Hiroaki Shimokawa
JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Hajime Aoyanagi, Kotaro Nochioka, Yasuhiko Sakata, Masanobu Miura, Takashi Shiroto, Ruri Abe, Shintaro Kasahara, Masayuki Sato, Takahide Fujihashi, Shinsuke Yamanaka, Hideka Hayashi, Koichiro Sugimura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Hematology
Shoko Ohura-Kajitani, Takashi Shiroto, Shigeo Godo, Yosuke Ikumi, Akiyo Ito, Shuhei Tanaka, Koichi Sato, Jun Sugisawa, Satoshi Tsuchiya, Akira Suda, Tomohiko Shindo, Shohei Ikeda, Kiyotaka Hao, Yoku Kikuchi, Kotaro Nochioka, Yasuharu Matsumoto, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Shinsuke Yamanaka, Yasuhiko Sakata, Kotaro Nochioka, Masanobu Miura, Shintaro Kasahara, Masayuki Sato, Hajime Aoyanagi, Takahide Fujihashi, Hideka Hayashi, Takashi Shiroto, Koichiro Sugimura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa
EUROPEAN JOURNAL OF HEART FAILURE
(2020)
Article
Cardiac & Cardiovascular Systems
Kyoshiro Fukasawa, Koji Fukuda, Nobuyoshi Mori, Masateru Kondo, Takahiko Chiba, Keita Miki, Yuhi Hasebe, Makoto Nakano, Hiroaki Shimokawa
Summary: The study shows that maintaining sinus rhythm with ablation can improve exercise tolerance in patients with paroxysmal atrial fibrillation, especially in those with reduced exercise tolerance.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Akira Suda, Andreas Seitz, Yuji Odaka, Anastasios Athanasiadis, Giancarlo Pirozzolo, Koichi Sato, Kiyotaka Hao, Raffi Bekeredjian, Jun Takahashi, Udo Sechtem, Hiroaki Shimokawa, Peter Ong
Summary: This study compared contemporary German and Japanese patients with coronary spasm, finding similarities in types of spasm and frequency of multivessel spasm between the two populations.