mTOR inhibitor reverses autistic-like social deficit behaviours in adult rats with both Tsc2 haploinsufficiency and developmental status epilepticus
出版年份 2016 全文链接
标题
mTOR inhibitor reverses autistic-like social deficit behaviours in adult rats with both Tsc2 haploinsufficiency and developmental status epilepticus
作者
关键词
Animal model, Autism spectrum disorder, Everolimus, Experimental therapy, Social cognition, Tuberous sclerosis complex
出版物
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
Volume 267, Issue 5, Pages 455-463
出版商
Springer Nature
发表日期
2016-06-05
DOI
10.1007/s00406-016-0703-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neurological and neuropsychiatric aspects of tuberous sclerosis complex
- (2015) Paolo Curatolo et al. LANCET NEUROLOGY
- Everolimus treatment of refractory epilepsy in tuberous sclerosis complex
- (2013) Darcy A. Krueger et al. ANNALS OF NEUROLOGY
- A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials
- (2013) Michael Wong Expert Review of Neurotherapeutics
- Modeling Transformations of Neurodevelopmental Sequences across Mammalian Species
- (2013) A. D. Workman et al. JOURNAL OF NEUROSCIENCE
- A systematic review of two outcomes in autism spectrum disorder - epilepsy and mortality
- (2012) SUE WOOLFENDEN et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
- (2012) Peter T. Tsai et al. NATURE
- Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex
- (2012) Atsushi Sato et al. Nature Communications
- Consequences of early life MK-801 administration: Long-term behavioural effects and relevance to schizophrenia research
- (2011) Ann Li Lim et al. BEHAVIOURAL BRAIN RESEARCH
- Epilepsy and Autism: Neurodevelopmental Perspective
- (2011) Roberto Tuchman et al. Current Neurology and Neuroscience Reports
- Epilepsy and Tsc2 Haploinsufficiency Lead to Autistic-Like Social Deficit Behaviors in Rats
- (2010) Robert Waltereit et al. BEHAVIOR GENETICS
- Psychiatric Disorders in Children with Earlier Infantile Spasms
- (2010) Raili Riikonen et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents
- (2009) Terence O’Reilly et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- The natural history of epilepsy in tuberous sclerosis complex
- (2009) Catherine J. Chu-Shore et al. EPILEPSIA
- Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats
- (2008) Miriam Schneider et al. ADDICTION BIOLOGY
- Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
- (2008) Ling-Hui Zeng et al. ANNALS OF NEUROLOGY
- Recent advances in neurobiology of Tuberous Sclerosis Complex
- (2008) Valerio Napolioni et al. BRAIN & DEVELOPMENT
- Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function
- (2008) L. Meikle et al. JOURNAL OF NEUROSCIENCE
- Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis
- (2008) Dan Ehninger et al. NATURE MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now