4.6 Article

Spirometry: A practical lifespan predictor of global health and chronic respiratory and non-respiratory diseases

期刊

EUROPEAN JOURNAL OF INTERNAL MEDICINE
卷 89, 期 -, 页码 3-9

出版社

ELSEVIER
DOI: 10.1016/j.ejim.2021.04.027

关键词

chronic obstructive pulmonary disease; lung development; non-communicable diseases; spirometry; global health; preterm birth; prevention

资金

  1. Chiesi Farmaceutici SpA - Chiesi Farmaceutici SpA

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The article proposes that spirometry is an overlooked global health marker that can be used to monitor human health and predict risks of chronic diseases. It emphasizes the importance of spirometry in assessing respiratory health and identifying individuals at risk of both respiratory and non-respiratory diseases. The authors suggest that spirometry can be a reproducible, non-invasive, safe, and affordable global health marker throughout the lifespan, serving as an early warning system to save lives.
Objectives. 1. To review and discuss available evidence supporting that spirometry is an overlooked global health marker, that could be used regularly through the lifespan to monitor human health and predict risk of chronic respiratory and other chronic non-communicable diseases (NCDs). 2. To discuss the challenges and opportunities that this proposal faces.Summary of key data. First, spirometry is essential to assess and monitor respiratory health. Second, spirometry adds prognostic value to other well-accepted health markers used in clinical practice, such as blood pressure, body mass index, glucose and blood lipids, by identifying individuals at risk, not only of respiratory diseases, but also of other NCDs, particularly cardiovascular and metabolic disorders. Conclusion. Although we acknowledge that research gaps still exist, we propose that spirometry assessed during childhood, adolescence and early and late adulthood can be a reproducible, non-invasive, safe and affordable global health marker to identify individuals in the general population at risk of respiratory and non-respiratory NCDs. In this context, spirometry may act as the caged canaries that miners used to carry into mines to alert them of dangerous accumulations of gases, thus providing an early warning and save lives.

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