Editorial Material
Biochemistry & Molecular Biology
Borja Quiroga
Summary: BPA, a common component of plastics worldwide, has been shown to act as an endocrine disruptor with some hormonal functions. High levels of BPA are related to cardiovascular events and carcinogenesis pathways, and CKD patients have higher serum concentrations of BPA due to impaired renal function. Efforts to reduce BPA levels in these patients include developing BPA-free dialysis filters and other techniques.
Review
Environmental Sciences
Julia de Morais Farias, Natascha Krepsky
Summary: This study reviewed the research on bacterial degradation of bisphenol analogues, finding that bacteria can degrade bisphenol analogues, especially bisphenol A. Sphingomonas, Sphingobium, and Cupriavidus are common degradation strains. The research is important for selecting suitable microorganisms for the bioremediation of bisphenol analogue pollution.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Eujung Kim, Minjung Song, Adam Gopal Ramu, Dongjin Choi
Summary: Bisphenol A (BPA), a common chemical used in plastic production, has emerged as a serious environmental concern due to its potential toxicity to plants. This study aimed to investigate the mechanism of BPA-induced root cells by examining the effects of BPA on the ultrastructure and function of soybean plant root tip cells. Changes in plant root cell tissues after BPA exposure were observed, and the accumulation of BPA in different plant parts was analyzed. The findings provide insight into how BPA can alter plant root growth.
Article
Environmental Sciences
Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Summary: Higher maternal bisphenol S urine concentrations, especially in the first trimester, seem to be associated with larger fetal head circumference, higher weight, and a lower risk of being small size for gestational age at birth. Other bisphenols were not consistently associated with fetal growth outcomes.
ENVIRONMENTAL HEALTH
(2021)
Review
Environmental Sciences
Tijana Vasiljevic, Tom Harner
Summary: BPA and its analogues are widely used in plastic synthesis, potentially disrupting the hormonal structure of living organisms. Reports on BPA levels in air are limited, mainly due to anthropogenic activities. China reported the highest outdoor air levels of BPA near a low-tech e-waste recycling site, and indoor dust also revealed bisphenol analogues used in BPA-free products.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Endocrinology & Metabolism
Giada Frenzilli, Joan Martorell-Ribera, Margherita Bernardeschi, Vittoria Scarcelli, Elisabeth Jonsson, Nadia Diano, Martina Moggio, Patrizia Guidi, Joachim Sturve, Noomi Asker
Summary: The study shows that both bisphenol A and its alternative bisphenol S can cause endocrine disrupting and genotoxic effects in brown trout, indicating two different mechanisms of damage underlying the activities of bisphenol A and bisphenol S. Bisphenol A primarily increases micronuclei frequency in fish erythrocytes, while bisphenol S may cause damage through other mechanisms.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Marcelino Perez-Bermejo, Irene Mas-Perez, Maria Teresa Murillo-Llorente
Summary: Bisphenol A, a common endocrine disruptor found in daily products, is linked to obesity and diabetes due to its ability to mimic natural estrogen. This compound can stimulate adipocyte hypertrophy and alter the endocrine system. Despite some countries implementing policies, there is a lack of international agreement on the regulation of Bisphenol A exposure.
Article
Environmental Sciences
Junjie Ao, Yongjie Liu, Weifeng Tang, Jun Zhang
Summary: This study investigates the potential effects and mechanisms of bisphenol S (BPS) exposure on human colon mucosal epithelial cells. The results show that BPS exposure increases the production of pro-inflammatory cytokines, destroys the tight junctions of the cells, and affects neurotransmitters. These findings suggest that BPS exposure may disrupt the balance of the gut-brain axis, leading to inflammatory cytokine production and tight junction destruction.
Article
Environmental Sciences
Yiwen Xu, Ailun Hu, Yiren Li, Yan He, Jianming Xu, Zhijiang Lu
Summary: A robust method was developed to accurately and quickly detect bisphenol A and 13 analogs in soil. The method was applied to 29 soil samples from 21 provinces in China, revealing 12 bisphenols with notably high concentrations, particularly bisphenol P which was at least ten times higher than in other environmental matrices. The results indicate hot spots of bisphenol pollution in soil, calling for further investigations.
Article
Chemistry, Analytical
Anna Raysyan, Rudolf J. Schneider
Summary: Bisphenol A is a crucial chemical in polymer plastics and coatings production. To address concerns about BPA toxicity, a latex microparticle-based lateral flow immunoassay method was developed for rapid on-site screening. The method showed high sensitivity and efficiency in detecting BPA.
Article
Reproductive Biology
Carolina Marques Bedolo, Thalles Fernando Rocha Ruiz, Gustavo Matheus Amaro, Patricia Simone Leite Vilamaior, Ellen Cristina Rivas Leonel, Sebastiao Roberto Taboga, Silvana Gisele Pegorin de Campos
Summary: This study aimed to describe the histopathological alterations in the prostate of adult female gerbils caused by perinatal exposure to BPA (50 μg/kg) and E2 (35 μg/kg). The results showed that both BPA and E2 induced proliferative lesions in the female prostate by modulating steroid receptors in the epithelium. BPA was also found to be a pro-inflammatory and pro-angiogenic agent, with more pronounced impacts in the prostatic stroma.
REPRODUCTIVE TOXICOLOGY
(2023)
Review
Toxicology
Henrique Eloi Costa, Elisa Cairrao
Summary: Bisphenol A (BPA) is a widely produced synthetic compound that can disrupt the endocrine system and have detrimental effects on the neurological system. Exposure to BPA can lead to oxidative stress, changes in gene and protein expression, neuronal damage, and increased risk of neurologic diseases such as stroke, Alzheimer's, and Parkinson's. Epidemiological studies have also shown that BPA exposure during neurodevelopment can contribute to the emergence of disorders such as ADHD, ASD, depression, and cognitive disorders.
ARCHIVES OF TOXICOLOGY
(2023)
Review
Environmental Sciences
Nadeem Ghani Khan, Jacinta Correia, Divya Adiga, Padmalatha Satwadi Rai, Herman Sunil Dsouza, Sanjiban Chakrabarty, Shama Prasada Kabekkodu
Summary: Bisphenol A is a synthetic chemical used for manufacturing plastics and resins, which has been linked to increased susceptibility to diseases, including cancer, at extremely low doses. Studies suggest that BPA may be a probable human carcinogen and exerts toxicological effects at genetic and epigenetic levels.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Siemon De Nys, Eveline Putzeys, Radu Corneliu Duca, Philippe Vervliet, Adrian Covaci, Imke Boonen, Marc Elskens, Jeroen Vanoirbeek, Lode Godderis, Bart Van Meerbeek, Kirsten L. Van Landuyt
Summary: The study successfully quantified the one-year release of BPA from four commercial materials using an optimized analytical method. Results showed that BPA continuously eluted from all tested composites over a year when ethanol was used as the extraction solvent, while in water, BPA release could be detected for up to a year but levels could not be accurately quantified after several weeks.
Article
Environmental Sciences
Junjie Ao, Xiaona Huo, Jiangtao Zhang, Yuchan Mao, Guohua Li, Jiangfeng Ye, Yuhua Shi, Fan Jin, Shihua Bao, Jun Zhang
Summary: The study indicates that environmental exposure to bisphenol analogues is associated with an increased risk of unexplained recurrent miscarriage (URM), with a dose-response pattern observed for BPAF, BPAP, and BPB. Older women, aged 30 years or above, may be more vulnerable to the effects of these chemicals.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Aurelie Lacouture, Camille Lafront, Cindy Peillex, Martin Pelletier, Etienne Audet-Walsh
Summary: EDCs can modulate the functions of sex-steroid receptors, indirectly impact androgen and estrogen pathways, and have multiple cellular targets beyond sex-steroid receptors, leading to various potential effects. This article reviews the association between prostate cancer and the endocrine-disrupting functions of four prominent EDC families, suggesting common guidelines for studying EDCs in the context of endocrine diseases.
ENVIRONMENTAL RESEARCH
(2022)
Review
Pharmacology & Pharmacy
Sophie Ramsay, Elisabeth Lapointe, Stephane Bolduc
Summary: Overactive bladder (OAB) is a chronic condition highly prevalent in children, and conservative measures should be the first line of treatment. When conservative management fails, pharmacological options are considered, although only two agents are currently approved for pediatric use. Treatment for OAB in children requires a structured, stepwise approach, active involvement of children and their families, and close monitoring of side effects and medication adherence.
EXPERT OPINION ON PHARMACOTHERAPY
(2022)
Article
Oncology
Stephane Chabaud, Eve Pellerin, Christophe Caneparo, Cassandra Ringuette-Goulet, Frederic Pouliot, Stephane Bolduc
Summary: The hypoxic condition during tumor growth has a significant impact on the survival and migration properties of bladder cancer cells. Low-grade bladder cancer cells tend to become more aggressive under hypoxic culture conditions, while high-grade cells tend to exhibit less aggressive characteristics. Hypoxia greatly alters the properties of bladder cancer cells, including matrix metalloproteinases expression and metabolic changes. Studying bladder cancer cells in hypoxic environments is vital for translating in vitro findings to an in vivo context.
Article
Oncology
Martial Millet, Enola Bollmann, Cassandra Ringuette Goulet, Genevieve Bernard, Stephane Chabaud, Marc-Etienne Huot, Frederic Pouliot, Stephane Bolduc, Francois Bordeleau
Summary: A study on the physical properties of tumors demonstrates that a 3D self-assembly bladder model constructed with cancer-associated fibroblasts can effectively recapitulate the biological and mechanical features of tumors. The model exhibited increased extracellular matrix content, remodeling, and stiffness in the stroma assembled by cancer-associated fibroblasts. Additionally, normal urothelial cells seeded on the tumor model displayed tumor-like responses, including increased cell proliferation, cell infiltration, and features of epithelial-to-mesenchymal transition.
Article
Microbiology
Charlene Roussel, Stephane Chabaud, Jacob Lessard-Lord, Valentina Cattero, Felix-Antoine Pellerin, Perrine Feutry, Valerie Bochard, Stephane Bolduc, Yves Desjardins
Summary: Uropathogenic Escherichia coli (UPEC) are the primary cause of recurrent urinary tract infections. The poor understanding of UPEC ecology-pathophysiology from its reservoir-the gut, to its infection site-the urothelium, partly explains the inadequate and abusive use of antibiotics to treat UTI, which leads to a dramatic upsurge in antibiotic-resistance cases. In this study, the effects of cranberry proanthocyanidins (PAC)-rich extract microbial metabolites on UPEC virulence and fitness were evaluated. The results demonstrated that PAC-rich cranberry extract microbial metabolites significantly reduce the activation of UPEC virulence genes in the gut reservoir, suggesting their potential in preventing UTI.
MICROBIOLOGY SPECTRUM
(2022)
Review
Biochemistry & Molecular Biology
David Brownell, Stephane Chabaud, Stephane Bolduc
Summary: Female gynecological organ dysfunction has a negative impact on the quality of life for women, and current treatment options are inadequate. Tissue engineering provides a potential alternative for repairing or replacing dysfunctional gynecological organs, with the aim of restoring female fertility and sexual wellbeing.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Eve Pellerin, Felix-Antoine Pellerin, Stephane Chabaud, Frederic Pouliot, Martin Pelletier, Stephane Bolduc
Summary: The study reveals that glucuronidated BPs have different effects on normal urothelial cells and bladder cancer cells. They decrease the activity of normal cells but increase the bioenergetics and activity of cancer cells. This suggests that the ubiquitous presence of BP metabolites in urine could promote the progression of bladder cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Saeed Farzamfar, Elissa Elia, Stephane Chabaud, Mohammad Naji, Stephane Bolduc
Summary: Electrospun scaffolds show great potential in urethral defect repair by mimicking native cells' niches and delivering drugs and cells, but there are still challenges and issues to be addressed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Christophe Caneparo, Stephane Chabaud, Julie Fradette, Stephane Bolduc
Summary: Growing demand in various industries has led to an increase in in vitro cell cultures. However, the use of fetal bovine serum comes with challenges such as unknown constitution, potential contamination, and limited production. A Serum-Free Medium (SFM) has been developed to address these issues. The study showed that SFM enables cell proliferation and is more suitable for epithelial cells compared to the traditional medium. However, further optimization is needed for fibroblast proliferation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Eve Pellerin, Felix-Antoine Pellerin, Stephane Chabaud, Frederic Pouliot, Stephane Bolduc, Martin Pelletier
Summary: This study evaluated the effects of BPA and BPS on the bioenergetics, proliferation, and migration of bladder urothelial cells and bladder cancer cells. The results showed that chronic exposure to BPA and BPS decreased energy metabolism in urothelial cells while increasing it in bladder cancer cells. This suggests that BPA and BPS exposure could promote bladder cancer development.
Review
Biochemistry & Molecular Biology
Elissa Elia, David Brownell, Stephane Chabaud, Stephane Bolduc
Summary: This passage discusses the similarities between the gastrointestinal and genitourinary tracts, which both consist of hollow structures that rely on muscle contractions to facilitate the flow of materials. It describes the anatomy, pathologies, and treatments of these organs, with a particular emphasis on tissue engineering strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Aurelie Lacouture, Yann Breton, Cindy Weidmann, Sarah-Maude Goulet, Lucas Germain, Martin Pelletier, Etienne Audet-Walsh
Summary: This study reveals the impact of estrogens and EDCs on mammary epithelial cell metabolism in monolayer and organoid cultures. It demonstrates that EDCs can alter bioenergetic fluxes and interfere with the regulation of estrogen target genes. The sensitivity of mammary organoids to specific EDCs can also be influenced by past pregnancies. Understanding the metabolic effects of EDCs is important for the development and function of the mammary gland.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Hematology
Martin Pelletier, Yann Breton, Isabelle Allaeys, Yann Becker, Tom Benson, Eric Boilard
Summary: The study reveals that extracellular vesicles released by activated platelets contain mitochondria, which can be captured by neutrophils and monocytes, enhancing their mitochondrial function. These external mitochondria may support other metabolic functions through transcellular bioenergetics.
Article
Environmental Sciences
Muqiu Hu, Xin Zhao, Jinghan Gu, Lulu Qian, Zhiqing Wang, Yuanyuan Nie, Xiaoyu Han, Long An, Haiqiang Jiang
Summary: Due to its simple process, environmental friendliness, and low operating costs, biometallurgy has become a popular technology for metals recovering from low-grade ores and tailings. An optimized agar was used to isolate and grow functional bacteria, resulting in the successful isolation of six functional stains. These strains were further tested for their ability to leach metals from polymetallic sulfide tailings, with significant improvements observed when the strains were mixed together. The selection of leaching process should be based on tailings composition and target metals.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Saqib Hassan, Aswin Thacharodi, Anshu Priya, R. Meenatchi, Thanushree A. Hegde, R. Thangamani, Ht Nguyen, Arivalagan Pugazhendhi
Summary: An Endocrine Disrupting Chemical (EDC) is a compound that disrupts the function of the endocrine system and is found in the environment. EDCs, such as Bisphenol A and pesticides, have been shown to have negative effects on the female reproductive system. Understanding the relationship between EDCs and women's health is crucial for developing strategies to protect reproductive health and informing public policy decisions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Lichang Zhou, Zhaoling Li, Boyi Cheng, Jinqi Jiang, Xinqi Bi, Zongping Wang, Guanghao Chen, Gang Guo
Summary: Thiosulfate can promote sulfur-mediated bacterial activity, inhibit glycogen accumulating organisms, and enhance denitrification efficiency. After the carbon source is reduced, the competitive ability of glycogen accumulating organisms increases, resulting in reduced sulfate reduction.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Claire E. Campbell, Devyn L. Cotter, Katherine L. Bottenhorn, Elisabeth Burnor, Hedyeh Ahmadi, W. James Gauderman, Carlos Cardenas-Iniguez, Daniel Hackman, Rob McConnell, Kiros Berhane, Joel Schwartz, Jiu-Chiuan Chen, Megan M. Herting
Summary: Recent studies have found a connection between air pollution and increased risk for behavioral problems during development. However, more longitudinal studies are needed to investigate how exposure during the transition to adolescence may affect emotional behaviors.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Jing-hong Liang, Ru-yu Yang, Mei-ling Liu, Ying-qi Pu, Wen-wen Bao, Yu Zhao, Li-xin Hu, Yu-shan Zhang, Shan Huang, Nan Jiang, Xue-ya Pu, Shao-yi Huang, Guang-hui Dong, Ya-jun Chen
Summary: This study examines the association between urban Green and blue spaces (GBS) exposure and Emotion and behavior problems (EBP) in youth populations. The findings suggest that higher exposure to GBS, particularly green spaces (GS) and blue spaces (BS), is associated with a decrease in the risk of developing total difficulties in young individuals. The joint effect of GS and BS may also contribute to the decrease in EBPs.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Diego Ruiz-Sobremazas, Mario Ruiz Coca, Miguel Morales-Navas, Rocio Rodulfo-Cardenas, Caridad Lopez-Granero, Maria Teresa Colomina, Cristian Perez-Fernandez, Fernando Sanchez-Santed
Summary: Air pollution is associated with a range of health issues and gestational exposure to environmental pollutants may be linked to neurodevelopmental disorders. This study investigated the effects of oral gestational exposure to particulate matter (PM) on ultrasonic vocalizations (USV). The findings suggest that this exposure may lead to social deficits and abnormal gene expression related to neurotransmitter systems. Further research is needed to better understand the effects of air pollution on neurodevelopmental disorders and the neurotransmission systems involved.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yagmur Kabakci, Sadiye Kosar, Ozgur Dogan, Fehmi Gorkem Uctug, Osman Atilla Arikan
Summary: This study investigated the effect of electrohydrolysis pretreatment on municipal solid waste. The results showed that applying electrohydrolysis pretreatment increased methane production and reduced the time required for hydrolysis, suggesting it is a promising method to improve anaerobic digestion efficiency.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Chuanwu Zhao, Yaozhong Pan, Hanyi Wu, Yu Zhu
Summary: This study analyzed the impact of industrial zones on urban heat islands using remote sensing images and a novel spectral index. The research found that the contraction or expansion of industrial zones has a significant effect on land surface temperature. The results are valuable for environmental assessment and fine management of industrial cities.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Bang Du, Zhongzhong Wang, Piet N. L. Lens, Xinmin Zhan, Guangxue Wu
Summary: This study investigated the performance, syntrophic relationships, microbial communities, and metabolic pathways of ethanol-fed reactors with different operational modes and solids retention times. The results showed that different microorganisms were enriched under different SRT conditions, and syntrophic bacteria related to methane production could be enriched under low SRT conditions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Gokulan Ravindiran, Sivarethinamohan Rajamanickam, Muralikrishnan Ramalingam, Gasim Hayder, Balamurugan Karupaiya Sathaiah, Madhava Krishna Reddy Gaddam, Senthil Kumar Muniasamy, Priya Arunkumar
Summary: The present study investigated the sustainable approach for wastewater treatment using waste algal blooms. The biochar produced by the marine algae Ulva reticulata was used to remove chromium, nickel, and zinc from aqueous solutions. The study examined the adsorbents' properties and stability using SEM/EDX, FTIR, and XRD. The results showed that the biochar had high removal efficiency for the toxic metals, and the packed bed column effectively removed the heavy metal ions. The Thomas and Adams-Bohart models were found to best fit the regression values, and desorption studies were conducted to understand the sorption and elution processes.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Vignesh Vinayagam, Kavitha Nagarasampatti Palani, Sudha Ganesh, Siddharth Rajesh, Vedha Varshini Akula, Ramapriyan Avoodaiappan, Omkar Singh Kushwaha, Arivalagan Pugazhendhi
Summary: The presence of pollutants in water contributes to global pollution and poses significant threats to humans and wildlife. Finding effective wastewater treatment techniques is crucial for reducing pollutant accumulation in the environment. This paper highlights recent advances in the electrochemical advanced oxidation method and other processes for treating pharmaceuticals, dyes, and pesticide-polluted effluents.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
M. M. M. Ahmed, Kai-Yue Chen, Fang-Yu Tsao, Yi-Cheng Hsieh, Yu-Ting Liu, Min Tzou
Summary: This study investigated the sorption of citric acid onto humic acid-iron hydr(o)xide coprecipitate (HAFHCP) and the reciprocal effects of citric acid and P sorption on HAFHCP. The results showed that citric acid could increase P availability and have an impact on P sorption.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Xibo Xu, Zeqiang Wang, Xiaoning Song, Wenjie Zhan, Shuting Yang
Summary: The selection of predictor variables is crucial in building a digital mapping model for potentially toxic elements (PTEs) in soil. Traditionally, spatial and spectral parameters have been used as predictor variables, but the temporal dimension is often overlooked. This study demonstrates the value of incorporating temporal indices in the model, leading to significant performance improvements. The temporal-spatial-spectral covariate combinations used in a random forest (RF) algorithm achieve satisfactory mapping accuracy and outperform other methods.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yan Pei, Xun Liu, Mengbo Cao, Zijun Wang, Hongbing Yang
Summary: Heteroatom doping can reconfigure the electronic structure of heterogeneous catalysts, leading to the development of advanced oxidation water purification materials with superior performance and stability. In this study, a series of catalysts with different elemental doping were prepared using a simple and environmentally friendly method. The S-doped NiCo2O4 catalyst showed excellent catalytic performance for the removal of Tetracycline, with significantly increased kinetic constant and high oxidation and mineralization efficiency in a wide pH range. The degradation process was dominated by non-radical oxidation pathway after S doping, and the overall process moved towards low toxicity.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Srivalli Thimmarayan, Harshavardhan Mohan, Gaddapara Manasa, Karthi Natesan, Shanmugam Mahendran, Pavithra Muthukumar Sathya, Byung-Taek Oh, R. Ravi Kumar, Rangasamy Sigamani Gandhimathi, Arul Jayaprakash, Kamala-Kannan Seralathan
Summary: This study investigated the bacterial degradation of naphthalene (NPT) isolated from crude oil-contaminated soil. Bacillus sp. GN 3.4, a potential bacteria for NPT biodegradation, was isolated and the optimal conditions for NPT degradation were determined. The study suggests that Bacillus sp. GN 3.4 could potentially aid in bioremediation by eliminating NPT from the soil.
ENVIRONMENTAL RESEARCH
(2024)