TFG binds LC3C to regulate ULK1 localization and autophagosome formation

TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes

(2020) Lisa Wetzel et al.   Nature Communications

TFG is required for autophagy flux and to prevent endoplasmic reticulum stress in CH12 B lymphoma cells

(2020) Tobit D. Steinmetz et al.   Autophagy

Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins

(2019) Martina Wirth et al.   Nature Communications

Selective Autophagy: ATG8 Family Proteins, LIR Motifs and Cargo Receptors

(2019) Terje Johansen et al.   JOURNAL OF MOLECULAR BIOLOGY

R106C TFG variant causes infantile neuroaxonal dystrophy “plus” syndrome

(2018) A. Catania et al.   NEUROGENETICS

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma

(2018) Concetta Quintarelli et al.   OncoImmunology

The ULK1-FBXW5-SEC23B nexus controls autophagy

(2018) Yeon-Tae Jeong et al.   eLife

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy

(2017) Xuezhao Liu et al.   JOURNAL OF CELL BIOLOGY

Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway

(2017) François Le Guerroué et al.   MOLECULAR CELL

MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins

(2017) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER–Golgi intermediate compartments

(2017) Michael G. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iLIR database: A web resource for LIR motif-containing proteins in eukaryotes

(2016) Anne-Claire Jacomin et al.   Autophagy

Novel Genetic, Clinical, and Pathomechanistic Insights into TFG-Associated Hereditary Spastic Paraplegia

(2016) Gaurav V. Harlalka et al.   HUMAN MUTATION

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation

(2016) Francesca Nazio et al.   JOURNAL OF CELL BIOLOGY

Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination

(2016) Chin-Chih Liu et al.   MOLECULAR CELL

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles

(2016) Eleftherios Karanasios et al.   Nature Communications

Sec24 phosphorylation regulates autophagosome abundance during nutrient deprivation

(2016) Saralin Davis et al.   eLife

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization

(2015) A. Johnson et al.   EMBO JOURNAL

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

(2015) Daniela Stadel et al.   MOLECULAR CELL

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes

(2015) Ignazio Caruana et al.   NATURE MEDICINE

A requirement for ER-derived COPII vesicles in phagophore initiation

(2014) Juan Wang et al.   Autophagy

Protein Secondary Structure Classification Revisited: Processing DSSP Information with PSSC

(2014) Jan Zacharias et al.   Journal of Chemical Information and Modeling

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

A novel TFG mutation causes Charcot-Marie-Tooth disease type 2 and impairs TFG function

(2014) P.-C. Tsai et al.   NEUROLOGY

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

(2014) Liang Ge et al.   eLife

FIP200 regulates targeting of Atg16L1 to the isolation membrane

(2013) Taki Nishimura et al.   EMBO REPORTS

The Atg8 family: multifunctional ubiquitin-like key regulators of autophagy

(2013) Moran Rawet Slobodkin et al.   Essays in Biochemistry

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

Dynamic association of the ULK1 complex with omegasomes during autophagy induction

(2013) E. Karanasios et al.   JOURNAL OF CELL SCIENCE

Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure

(2013) C. Beetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

The TRK-Fused Gene Is Mutated in Hereditary Motor and Sensory Neuropathy with Proximal Dominant Involvement

(2012) Hiroyuki Ishiura et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex

(2012) Endalkachew Ashenafi Alemu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex–dependent and –independent autophagy

(2012) Noor Gammoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Sequential interactions with Sec23 control the direction of vesicle traffic

(2011) Christopher Lord et al.   NATURE

TFG-1 function in protein secretion and oncogenesis

(2011) Kristen Witte et al.   NATURE CELL BIOLOGY

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Autophagosome Formation Depends on the Small GTPase Rab1 and Functional ER Exit Sites

(2010) Felipe Carlos Martín Zoppino et al.   TRAFFIC

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Proline-rich Sequence Recognition

(2009) Andreas Schlundt et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY